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Article

Calibrated Deep-Learning Risk Indexing and Latent Behavioural Profiling for Occupational Mental-Health Risk Assessment

1
Department of Computer Science, CECOS University of IT and Emerging Sciences, Peshawar 25100, Pakistan
2
Department of Electrical Engineering, CECOS University of IT and Emerging Sciences, Peshawar 25100, Pakistan
3
Department of Computer Engineering, College of Computer Sciences and IT, King Faisal University, Al Ahsa 31982, Saudi Arabia
4
Department of Mechanical Engineering, University of Engineering and Technology, Mardan 23200, Pakistan
5
Department of Computer Engineering, Faculty of Engineering and Natural Sciences, Istanbul Atlas University, Istanbul 34408, Turkey
*
Author to whom correspondence should be addressed.
Bioengineering 2026, 13(6), 626; https://doi.org/10.3390/bioengineering13060626
Submission received: 5 May 2026 / Revised: 23 May 2026 / Accepted: 24 May 2026 / Published: 27 May 2026
(This article belongs to the Special Issue Computational Intelligence for Healthcare)

Abstract

Occupational mental-health risk in knowledge-work settings is an important public-health and psychosocial-support concern because workload demands, career insecurity, limited mentoring, uneven institutional support and barriers to care can increase psychological risk, including in early-career academic environments. Workplace well-being assessments rely on aggregate survey summaries or conventional prediction models, limiting calibration, interpretability, subgroup evaluation and transfer validation. This study develops a computational-intelligence framework for public mental-health decision support using heterogeneous workplace survey data with early-career academics treated as a motivating knowledge-work context rather than as the direct empirical cohort. The proposed approach combines attention-based tabular learning, variational autoencoder latent profiling, stacked ensemble prediction, probability calibration, feature attribution, perturbation analysis, fairness assessment and cross-dataset adaptation. Calibrated probabilities are converted into a transparent 0–100 risk index to support preventive outreach, psychosocial-support planning and resource-allocation decisions. The model is compared with baselines, including logistic regression, support vector machine, random forest, XGBoost, LightGBM, CatBoost, TabNet, FT–Transformer, NODE and DCN. Results show strong held-out performance with AUC = 0.885, average precision = 0.872, F1 = 0.808, Brier score = 0.145 and expected calibration error = 0.022, outperforming tested baselines. Five-fold robustness analysis produced a conservative mean test AUC of 0.809 ± 0.044 , indicating moderate partition sensitivity. Key predictors include work interference, perceived stress, care access and support variables. Latent profiling identifies two behavioural subgroups with distinct risk patterns. After feature harmonization, target-domain adaptation and recalibration, external evaluation on an occupational burnout dataset achieves AUC = 0.941 and average precision = 0.936, supporting calibrated, interpretable and subgroup-aware decision support under dataset shift.

1. Introduction

1.1. Occupational Stress as a Data-Intensive Public Health Problem

Occupational stress has become a major determinant of mental health and workforce sustainability and institutional performance within knowledge-intensive environments [1]. This problem becomes more important in high-pressure professional settings because productivity expectations, role ambiguity, job insecurity, social support and access to care jointly shape psychological risk. Academic work provides a strong example of knowledge-work stress because professional identity, scientific productivity, teaching responsibility, administrative demand and career uncertainty remain tightly connected [2]. Early-career researchers may face publication pressure, competitive funding environments, insecure contracts, limited autonomy and uneven mentoring access which together increase occupational vulnerability [3]. These pressures can gradually accumulate into chronic stress, emotional exhaustion, anxiety symptoms, depressive symptoms, reduced engagement and intention to leave the profession. Neuroimaging evidence further suggests that stress severity is associated with distinct brain activation patterns which are illustrated in Figure 1.
The mental health burden linked with occupational stress is not only an individual clinical concern because it also reflects a broader public health challenge shaped by organizational structures, resource allocation, stigma and confidentiality concerns and timely care access [5]. The workplace therefore becomes a sociotechnical setting where psychosocial exposures are produced and amplified and sometimes mitigated through institutional policies and support systems. Swarm-based coordination research also shows how complex adaptive systems can support structured evaluation and decision support under uncertain conditions [6]. An illustrative occupational-stress setting is shown in Figure 2 where acute work stress was examined within a controlled group-office environment.
High workload, limited job control, weak supervisor support, unclear career pathways and confidentiality uncertainty may reduce help-seeking behaviour while delaying timely intervention [7]. Supportive supervision, transparent policies, accessible services, flexible work arrangements and psychologically safe environments can instead reduce risk while improving resilience across vulnerable occupational groups. These patterns indicate that occupational mental health should be studied as a complex sociotechnical system rather than as isolated symptoms or individual weakness [8]. Efficient intrusion-detection research further illustrates how adaptive monitoring can support risk recognition in complex networked environments, which conceptually supports structured occupational-risk detection [9]. The COVID-19 pandemic also demonstrated the importance of healthcare data analytics for public-health decision support because data integration, predictive modelling, risk monitoring and resource planning became essential during rapidly changing healthcare conditions [10].
Figure 2. Floor plan and images of the open-office environment used in an acute work-stress experiment: (a) floor plan of the laboratory/open-office layout, (b) view of the workstation arrangement, and (c) view of the participant work area during the experiment. The colors in the floor plan indicate different spatial zones, workstation positions, and layout components used to distinguish areas within the experimental office environment. Adapted from Kerr et al. [11].
Figure 2. Floor plan and images of the open-office environment used in an acute work-stress experiment: (a) floor plan of the laboratory/open-office layout, (b) view of the workstation arrangement, and (c) view of the participant work area during the experiment. The colors in the floor plan indicate different spatial zones, workstation positions, and layout components used to distinguish areas within the experimental office environment. Adapted from Kerr et al. [11].
Bioengineering 13 00626 g002
Traditional workplace well-being assessment often relies on periodic surveys, aggregate descriptive statistics and broad risk categories which provide useful monitoring but limited individual or subgroup insight. These approaches become insufficient when the objective is to identify heterogeneous risk profiles, detect nonlinear interactions among stressors and support targeted preventive action. Knowledge-work populations differ across occupation, organization size, country, gender, work arrangement, career stage and support availability, which means average estimates can hide important subgroup patterns [12]. Scalable computational methods are therefore needed to convert heterogeneous workplace survey signals into interpretable risk information that can support prevention, outreach and policy design while preserving the social meaning of mental-health data.

1.2. Computational Intelligence for Interpretable Risk Modelling

Computational intelligence provides a practical route for modelling complex psychosocial risk because it can integrate demographic, behavioural, occupational and organizational variables within a unified analytical framework. Machine learning is especially useful for tabular survey data when stress-related outcomes emerge from interacting effects rather than independent linear relationships [13]. Workload interference may have different implications depending on supervisor support, care access, remote-work status, organizational culture and previous help-seeking experience. Such dependencies require flexible representations that remain understandable to researchers and decision makers who must interpret risk patterns responsibly.
Attention-based tabular models are well suited to this problem because they learn embeddings for sparse categorical variables, capture contextual feature relationships and model higher-order interactions where feature importance varies by respondent context [14]. Sparse-attention mechanisms can further support structured tabular learning by emphasizing informative variables while reducing the influence of noisy or weakly relevant predictors [15]. Image steganalysis research also demonstrates that attention mechanisms can improve pattern recognition when important signals are subtle and distributed across complex inputs [16]. Occupational mental-health risk often emerges from cumulative stressors involving workload, stigma, care access, support, anonymity and personal history, which makes attention-based learning useful for nuanced risk stratification [17]. Attribution analysis, attention analysis, latent profiling, perturbation testing and subgroup evaluation are therefore needed to verify whether predictions reflect meaningful occupational signals rather than unstable artefacts [18].
The present work develops an interpretable deep-learning risk index for occupational mental-health modelling using heterogeneous workplace survey data and calibrated probability outputs. Calibrated probabilities are mapped onto a transparent 0–100 score so that risk outputs become easier to interpret for non-technical stakeholders and institutional decision makers. Engine-failure prediction research also demonstrates how calibrated risk-oriented modelling can support early warning and decision support in complex operational settings [19]. This formulation relates to MEGA-style healthcare risk indexing where heterogeneous signals are translated into actionable risk scores for decision-support applications [20]. Attention-guided abnormal-pattern detection provides an additional reference because it supports robust identification of high-risk patterns under complex input conditions [21].
The proposed framework is methodologically aligned with topology-aware temporal modelling because both approaches seek to capture structured dependencies among complex features [22]. Temporal network prediction provides additional conceptual support because evolving relationships can improve predictive structure within dynamic systems [23]. Early abnormal-pattern identification in public-health settings further supports preventive modelling where risk is detected before outcomes become severe [24]. Unsupervised anomaly detection also motivates latent high-risk pattern discovery because important profiles may not be fully captured by predefined labels [25]. Explainable vision-transformer research further reinforces the need to connect deep representation learning with interpretable outputs for high-stakes decision contexts [26].
Recent deep-learning studies also support the broader design logic of the proposed occupational risk framework. Multiscale feature learning shows how complex signals can be represented across several levels of abstraction [27]. Convolution-based representation extraction remains useful when local patterns carry predictive information within structured input spaces [28]. Wireless vehicle modelling further demonstrates that learned representations can generalize across diverse signal environments and predictive domains [29]. Hybrid CNN–Transformer integration is relevant because it combines local feature extraction with long-range dependency modelling for complex sequence and pattern tasks [30]. Dense-sparse coding shows how compact feature representations can improve downstream prediction while reducing irrelevant variation [31]. Difficulty-aware fine-grained prediction is useful when observations vary in ambiguity and classification difficulty across heterogeneous cases [32]. Adaptive cross-channel dependency learning also motivates treating survey variables as interacting signals rather than independent predictors [33].
Early-career academics motivate the study, while the empirical task remains broader with occupational risk prediction from workplace survey signals across mental-health and burnout datasets. The proposed framework combines attention-enhanced prediction, latent representation learning, ensemble calibration and explanation for preventive decision support [34]. This decision-support perspective relates to social-feedback-aware behavioural modelling in online health contexts where behavioural signals help explain professional participation and user response patterns [35]. It also connects with online fitness socializing research where social interaction data are used to interpret health-related behaviour and engagement patterns [36]. Knowledge-enhanced cross-modal medical representation learning provides another methodological reference because it integrates heterogeneous health-related signals into richer predictive representations [37].

1.3. Study Rationale and Contributions

This study is motivated by the need to connect predictive analytics, psychosocial assessment and institutional decision making within occupational mental health. Existing well-being initiatives often respond after distress has become severe, while conventional survey summaries may lack the granularity required for early prevention. A computational risk framework can help identify elevated occupational stress, distinguish lower-risk and higher-risk profiles and highlight organizational conditions associated with increased risk. Such a framework is particularly relevant to knowledge-intensive populations including early-career academics, while empirical validation in this study uses broader workplace mental-health and burnout datasets.
This study therefore makes three connected contributions that address prediction and profiling and validation together. First the study develops a calibrated risk-prediction pipeline using heterogeneous workplace survey features that represent demographic, occupational, behavioural and support-related conditions. Second the study applies representation learning and clustering to identify latent occupational-stress profiles characterized by differences in support, work interference, stress burden and care access. Third the study evaluates robustness through cross-validation, perturbation analysis, subgroup fairness assessment and transfer testing across occupational mental-health datasets. The overall study flow is summarized in Figure 3 where survey data are preprocessed and passed through two complementary branches for calibrated risk prediction and latent-profile discovery. The resulting risk index, occupational-stress profiles, explainability outputs and fairness checks provide a transparent basis for preventive decision support.
The remainder of this paper is organized so that Section 2 reviews relevant studies and gaps, while Section 3 describes the proposed framework, Section 4 presents the results, Section 5 discusses implications and comparisons and Section 6 concludes with limitations and future work.

2. Related Work

2.1. Computational Approaches to Occupational and Public Mental Health

Mental health research has increasingly adopted computational methods to analyse behavioural, clinical, social and organizational data for risk understanding and decision support [38]. This shift from retrospective description toward anticipatory analytics is particularly relevant because psychological risk often develops gradually through interacting social, occupational and behavioural factors. Occupational mental-health studies consistently identify workload, job insecurity, low control, stigma, poor managerial support and limited care access as recurring determinants of distress. Academic work shares these risks while also including pressures related to publication expectations, grant competition, disciplinary reputation, mobility and precarious career progression [39].
Early-career researchers often face high performance expectations while having limited influence over institutional policies which can intensify stress and reduce help-seeking when confidentiality or career consequences are major concerns [40]. Smart predictive-maintenance research also illustrates how early-warning logic can support timely intervention before system-level deterioration becomes severe [41]. These findings make early-career academics an important motivating context for occupational mental-health decision support even when model development uses broader workplace survey data. Many applied studies rely on regression models, descriptive comparisons and conventional machine-learning methods such as random forests, gradient boosting and support vector machines. Multiclass support-vector classification with active learning also provides a related example of robust classification under complex feature conditions [42]. As multi-source health and behavioural data become more available, computational intelligence can uncover patterns that are difficult to detect manually, while these models must remain interpretable, clinically cautious, fairness-aware and aligned with preventive institutional uses [43]. Secure federated-learning research further reinforces the importance of privacy-preserving analytics when sensitive health-related data are used for predictive modelling [44].

2.2. Deep Learning for Heterogeneous Tabular Health Data

Deep learning has advanced imaging, biosignal analysis, natural language processing and multimodal health analytics, while its application to tabular health data remains more challenging because such data include mixed variable types, missingness, high-cardinality categorical fields, modest sample sizes and complex feature dependencies [45]. Transformer-based biomedical research also shows how attention mechanisms can support flexible representation learning across heterogeneous health-related tasks [46]. Recent tabular neural architectures including attention-based models, masked feature-selection networks, differentiable decision structures and hybrid ensembles have improved modelling of heterogeneous structured data where interactions among variables are central [47]. Attention mechanisms are particularly useful for survey-based mental-health modelling because they allow feature importance to vary across respondents and contexts. This capability is consistent with review evidence showing that attention-based deep-learning frameworks can support adaptive feature weighting in complex physiological and behavioural modelling tasks [48]. EEG fatigue-review evidence also supports the broader relevance of attention-guided learning for modelling complex human-state signals [49]. Entropy-informed residual modelling further demonstrates that nonlinear human-state dynamics can be captured through deep architectures when physiological variation is complex [50].
In occupational stress analysis the same exposure may carry different implications depending on supervisory support, anonymity, benefits, remote-work status and previous mental-health history [51]. Attention-based tabular learning therefore provides a flexible mechanism for capturing respondent-specific feature relevance and conditional dependencies that conventional models may miss [52]. Representation learning further supports latent subgroup discovery because compressed embeddings can preserve behavioural and organizational structure in lower-dimensional spaces. Generative augmentation can support imbalanced tabular learning although synthetic data must be evaluated carefully because poor reconstruction of continuous variables or joint dependencies can distort risk patterns [53]. Recent deep-learning studies further show that recurrent architectures, hybrid CNN-DNN mechanisms, stacked ensembles and multihead feature-extraction frameworks can strengthen representation learning and classification in complex pattern-recognition tasks.
Bidirectional recurrent modelling demonstrates how sequential dependencies can improve prediction when temporal structure is informative [54]. Hybrid Android-detection research illustrates the value of combining complementary neural components for improved classification under complex feature conditions [55]. Stacked ensemble malware-detection work provides evidence that layered predictive systems can improve robustness across challenging classification settings [56]. Multihead feature-extraction frameworks also support the idea that different representation channels can capture complementary aspects of heterogeneous input data [57].

2.3. Interpretability, Calibration, Fairness and Transferability

Responsible use of computational intelligence in mental health requires more than strong classification accuracy because model outputs may influence support allocation and institutional decision making [58]. Interpretability methods such as SHAP, integrated gradients, feature perturbation and attention analysis help identify whether predictions are driven by plausible psychosocial and organizational factors. Calibration is equally important because predicted probabilities should correspond to observed outcome frequencies before being converted into decision thresholds or operational risk bands [59]. Uncertainty-aware active learning further supports the need to quantify uncertainty when predictive systems are deployed in complex decision-support settings [60]. Improved KNN-based classification also demonstrates the value of robust baseline learning when high-stakes classification tasks require stable decision boundaries [61]. Adaptive swarm optimization provides another reference for improving search and optimization under complex operational constraints [62]. False-alarm reduction research further supports careful threshold design when decision-support systems must avoid unnecessary alerts and missed risks [63].
Fairness and transferability remain central challenges because subgroup differences in culture, care access, help-seeking, reporting behaviour, gender, employment context and region can produce unequal error patterns that aggregate metrics conceal [64]. Subgroup AUC, true-positive-rate differences, true-negative-rate differences and calibration gaps are therefore needed to evaluate whether risk estimates behave equitably across worker groups [65]. Models trained in one institutional or regional setting may also fail under domain shift, which makes local validation, transfer testing and fine-tuning necessary before practical deployment [66]. These gaps motivate the present framework because it integrates calibrated risk indexing, interpretable attention-based modelling, variational-autoencoder-based latent profiling, ensemble prediction, fairness evaluation and transfer validation within one occupational mental-health decision-support pipeline. Table 1 compares mental-health risk modelling studies with the proposed framework.

3. Methodology

This section presents the pipeline used to build an interpretable occupational mental-health risk index from heterogeneous workplace survey data. The workflow covers cohort construction, preprocessing, attention-based tabular learning, probability calibration, latent behavioural profiling, ensemble inference, fairness assessment, feature harmonization for external validation, transfer learning and reproducibility control. Early-career academics are used as a motivating high-pressure knowledge-work context; however, the empirical development and validation datasets are broader workplace mental-health and occupational burnout cohorts rather than direct early-career academic samples. The main data, preprocessing, evaluation and configuration details are given in Table 2, Table 3, Table 4 and Table 5.

3.1. Data Source, Cohort Construction and Outcome Definition

The analysis used a multi-country workplace mental health survey containing demographic, occupational, behavioural, access-to-care and help-seeking variables. The dataset was used as a development cohort for modelling occupational mental-health risk signals rather than as a direct sample of early-career academics. Table 2 summarizes the dataset, outcome, coverage and modelling role.
The supervised outcome is defined in Equation (1). It combines diagnosis, treatment, help-seeking and psychosocial support-need signals into one binary label. This outcome is interpreted as an operational indicator of elevated occupational mental-health support need rather than as a clinical diagnosis.
y i = I ω d d i + ω t t i + ω h h i + ω s q i τ y , q i = 1 L i = 1 L i ρ I r i , R +
Here, y i is the outcome for respondent i, d i is reported diagnosis, t i is treatment or care use, h i is recent help-seeking and q i is the normalized psychosocial support-need score. The terms r i , , R + , ρ , ω d , ω t , ω h , ω s and τ y denote item response, elevated-risk response set, item weight, domain weights and threshold.

3.2. Preprocessing, Missingness Encoding and Mixed-Feature Representation

Table 3 summarizes preprocessing and training. Numerical variables were median-imputed and standardized using training statistics. Categorical variables were indexed and embedded. Missingness masks, composite features and filtered predictors were retained for modelling. These steps were applied consistently across model families to ensure that differences in performance reflected model behaviour rather than inconsistent feature preparation.
The mixed representation is defined in Equation (2). It concatenates categorical embeddings, standardized numerical features, missingness masks and composite indicators so that demographic, occupational, support-related and access-to-care signals can be represented in a unified modelling space.
z i = j = 1 C E j o c i , j k = 1 N m i , k n i , k + 1 m i , k μ k tr μ k tr σ k tr + ϵ , m i , k g i
Here, z i is the respondent representation, E j is the embedding matrix, o ( c i , j ) is the one-hot category vector, n i , k is the numerical value, m i , k is the missingness indicator, μ k tr and σ k tr are training statistics and g i contains engineered composites. The composites used in Equation (2) are defined in Equation (3). They summarize workload, support, barriers and access-to-care conditions that are relevant across occupational mental-health contexts.
g i = η w a W α a x ˜ i , a a W | α a | , η s b S β b x ˜ i , b b S | β b | , η b c B δ c x ˜ i , c c B | δ c | , η a d A κ d x ˜ i , d d A | κ d |
Here, W , S , B and A denote workload, support, barrier and access feature sets. The weights α a , β b , δ c , κ d control item contribution and η w , η s , η b , η a scale each domain.

3.3. Attention-Based Tabular Risk Model

The main model uses attention-based tabular learning to capture nonlinear and context-dependent feature relations among workplace, behavioural and support-related variables. Figure 4 summarizes the path from mixed inputs to attention learning, calibration, explanation, latent modelling and ensemble inference.
The contextual representation is defined in Equation (4). It uses multi-head attention, residual connections, layer normalization and feedforward transformation. This architecture allows the model to represent interactions among occupational stressors, support indicators, access-to-care variables and respondent characteristics.
A i , h ( ) = softmax Q i , h ( ) K i , h ( ) + B h ( ) d h V i , h ( ) , U i ( ) = LN H i ( 1 ) + W O ( ) A i , 1 ( ) A i , H ( ) , H i ( ) = LN U i ( ) + W 2 ( ) φ W 1 ( ) U i ( ) + b 1 ( ) + b 2 ( )
Here, H i ( ) is the layer- representation, initialized from z i . The terms Q , K and V are attention projections; d h is head dimension; B , W and b are trainable parameters; and LN denotes layer normalization. The pooled respondent vector and raw probability are defined in Equation (5).
α i = softmax v p tanh W p H i ( L ) + b p , h ¯ i = t = 1 T α i , t H i , t ( L ) , p ^ i = σ w r Dropout h ¯ i + b r
Here, α i is the pooling-weight vector, h ¯ i is the respondent embedding, T is the number of tokens and p ^ i is the uncalibrated risk probability. The supervised objective is shown in Equation (6). It combines weighted focal loss, label smoothing and regularization to support learning under class imbalance while reducing overconfident predictions.
L sup = 1 M i = 1 M λ 1 y i ϵ 1 p ^ i γ log p ^ i + ϵ + λ 0 1 y i ϵ p ^ i γ log 1 p ^ i + ϵ + Ω Θ
Here, M is batch size, y i ϵ is the smoothed label, λ 1 and λ 0 are class weights, γ is the focal parameter, p ^ i is from Equation (5) and Ω ( Θ ) is regularization.

3.4. Probability Calibration and Risk Index Mapping

The raw probability from Equation (5) is calibrated before risk-index conversion. Calibration aligns predicted probabilities with observed event frequencies and is therefore essential before using model outputs for risk communication or decision support. The calibrated probability and risk index are defined in Equation (7).
s i =   σ a logit clip p ^ i , ϵ , 1 ϵ + b , RI i =   100 · s i s min val s max val s min val + ϵ , Band i =   q = 1 4 q I κ q 1 RI i < κ q
Here, s i is the calibrated probability, p ^ i is from Equation (5), a and b are validation-fitted calibration parameters, RI i is the 0–100 score and Band i is the risk band. Operationally, calibration was performed on the validation partition after model training. The uncalibrated neural-network output was first clipped to avoid numerical instability, transformed using the logit function and then passed through a validation-fitted Platt-scaling model. The calibrated probability was then linearly mapped to a 0–100 risk-index scale using the minimum and maximum calibrated probabilities observed in the validation set. This procedure separates three quantities: the raw model score, the calibrated probability and the final communication-oriented risk index. The score is intended as an interpretable occupational risk index for support prioritization rather than as a diagnostic measure or automatic intervention rule.

3.5. Latent Behavioural Profiling and Synthetic Data Generation

A variational autoencoder is used to learn latent occupational–behavioural profiles linked to support, workload interference, stigma and access-to-care patterns. This latent representation strategy is consistent with broader deep-learning evidence showing that sequential recurrent learning can extract compact patterns from complex input spaces [54]. Hybrid CNN-DNN mechanisms provide related evidence that complementary neural components can improve discriminative representation learning [55]. Topology-aware graph convolution further supports the modelling of structured dependencies across complex feature spaces [22]. Temporal network modelling also shows how evolving relationships can be represented for predictive learning under dynamic conditions [23]. Unsupervised anomaly detection provides additional support for discovering compact high-risk patterns without relying only on predefined labels [25]. These profiles are intended to summarize recurring workplace risk configurations rather than to define fixed clinical subtypes. Latent subgroups were interpreted descriptively by comparing cluster-level distributions of calibrated risk, work interference, stress burden, support availability, care-access variables and stigma-related indicators. Therefore, a cluster label does not represent a diagnosis or a stable psychological category. Instead, it represents a recurring pattern of workplace survey responses that may help explain whether elevated risk is mainly associated with work interference, limited support, care-access barriers or related occupational conditions. The mixed-type VAE objective is given in Equation (8).
L VAE = E q ϕ u i z i k N n ˜ i , k n ^ i , k 2 2 σ k 2 + j C CE c i , j , π ^ i , j + β KL q ϕ u i z i p u i , q ϕ u i z i = N μ ϕ z i , diag σ ϕ 2 z i
Here, L VAE combines numerical reconstruction, categorical reconstruction and KL regularization. The latent vector is u i and β controls the reconstruction–regularization balance. Latent profile assignment is defined in Equation (9).
p u i =   k = 1 K π k N u i μ k , Σ k , γ i , k =   π k N u i μ k , Σ k r = 1 K π r N u i μ r , Σ r , C i =   arg max k γ i , k
Here, K is the number of clusters, π k is the mixture weight, μ k and Σ k are cluster parameters, γ i , k is cluster responsibility and C i is the assigned profile. Synthetic samples are generated and checked using Equation (10). They are used only for robustness and augmentation experiments after validation and not as a substitute for real workplace mental-health observations.
u k ( s ) N μ k , Σ k , x ˜ ( s ) p ψ x u k ( s ) , Δ dist = m = 1 P ξ m D m P real m , P syn m
Here, u k ( s ) is a sampled latent vector, x ˜ ( s ) is the decoded record and Δ dist measures real–synthetic distributional mismatch.

3.6. Stacked Ensemble, Transfer Learning and Validation Metrics

The final model combines attention-based tabular learning, TabNet-style feature selection, neural oblivious decision ensembles and deep-cross interaction models. This design follows a stacked ensemble rationale where complementary learners are combined to improve classification robustness across complex structured inputs [56]. It also follows a multihead feature-extraction rationale where different representation heads capture complementary aspects of heterogeneous survey data [57]. This ensemble design is used to compare complementary representations of structured workplace survey data while improving robustness beyond a single neural architecture. Table 4 lists the evaluation, calibration, latent profiling, fairness and transfer procedures.
The stacked ensemble is defined in Equation (11). Bootstrap confidence intervals and the DeLong test were selected because they address complementary aspects of model evaluation. Bootstrap confidence intervals provide a non-parametric estimate of uncertainty for performance metrics such as AUC, average precision, F1 score, Brier score and calibration error by repeatedly resampling the test set with replacements. This strategy supports robust performance reporting when metric distributions may be non-normal or influenced by class imbalance. Recent deep-learning work on complex biomedical signal classification has similarly emphasized rigorous performance evaluation for reliable model validation, including entropy-informed residual-network evaluation for fine-grained EEG driver-state recognition [50]. In contrast, the DeLong test was used specifically for paired ROC-AUC comparison because it accounts for the correlation between models evaluated on the same test respondents. Together, bootstrap confidence intervals quantify the stability of individual performance estimates, whereas the DeLong test evaluates whether observed AUC differences between competing models are statistically meaningful.
m i =   p ^ i Tab , p ^ i TabNet , p ^ i NODE , p ^ i DCN , s i , p ^ i meta =   σ w m m i + b m , L meta =   1 M i = 1 M y i log p ^ i meta + 1 y i log 1 p ^ i meta + λ m w m 2 2
Here, m i contains component predictions and s i from Equation (7). The meta-learner produces p ^ i meta using regularized logistic fusion. The transfer-learning process is shown in Figure 5.
The adaptation objective is given in Equation (12).
Θ s * =   arg min Θ L s Θ ; D s , Θ s t * =   arg min Θ L t Θ ; D t + λ θ Θ F Θ s , F * 2 2 + λ d MMD 2 H s , H t , Δ A s t =   A Θ s * , D t test A Θ s t * , D t test
Figure 5. Cross-domain transfer learning and domain generalization process, including source-domain training, partial layer freezing, target-domain fine-tuning, target evaluation, divergence measurement, AUC-drop calculation and comparison against pooled global and target-only baselines.
Figure 5. Cross-domain transfer learning and domain generalization process, including source-domain training, partial layer freezing, target-domain fine-tuning, target evaluation, divergence measurement, AUC-drop calculation and comparison against pooled global and target-only baselines.
Bioengineering 13 00626 g005
Here, Θ s * is the source model, Θ s t * is the adapted model, D s and D t are source and target datasets and MMD measures domain alignment. Fairness and subgroup reliability are assessed using Equation (13).
Δ AUC =   max g G A g min g G A g , Δ TPR =   max g G i : g i = g I y ^ i = 1 , y i = 1 i : g i = g I y i = 1 + ϵ min g G i : g i = g I y ^ i = 1 , y i = 1 i : g i = g I y i = 1 + ϵ , Δ CAL =   max g G E s i y i g i = g
Here, G is the subgroup set, A g is subgroup AUC, y ^ i is the predicted label, y i is from Equation (1) and s i is from Equation (7).

3.7. Interpretability, Robustness and Reproducibility

Interpretability used global and local attribution, attention inspection, integrated gradients and perturbation tests. These analyses were included to evaluate whether the model relied on plausible occupational and support-related signals rather than unstable artefacts. Table 5 lists the main settings and reproducibility controls.
The attribution framework is defined in Equation (14).
f x i =   ϕ 0 + j = 1 D ϕ i , j , IG i , j =   x i , j x j 0 1 f x + α x i x x i , j d α , S ϕ =   2 K cv K cv 1 a < b corr rank ϕ ( a ) , ϕ ( b )
Here, ϕ i , j is the SHAP contribution, IG i , j is integrated-gradient attribution and S ϕ measures attribution-rank stability across folds. Perturbation robustness is defined in Equation (15).
Δ A j = A X , y A X j π , y , R j = Δ A j r = 1 D Δ A r + ϵ
Here, Δ A j is the AUC change after perturbing feature j and R j is normalized perturbation importance. The final workflow links Table 2, Table 3, Table 4 and Table 5 and Equations (1)–(15) into one computational system for calibrated, interpretable and subgroup-aware occupational risk modelling.

3.8. Comparison with State-of-the-Art Baseline Models

The proposed calibrated attention-latent ensemble was compared with conventional and neural baselines for heterogeneous tabular occupational-risk prediction. All models used the same data partitions and preprocessing steps and metrics defined in Section 3.2 and Table 4. Support vector machine classification was included because margin-based methods remain useful structured-data baselines and active-learning extensions can improve decision-boundary optimization [42]. The protocol also considered uncertainty-aware sampling for reliability assessment [60]. Robust KNN-based classification was included as an additional conventional comparator [61]. Adaptive optimization and false-alarm-aware classification further motivated the robustness checks used in the evaluation design [62]. Threshold reliability was also assessed because false alarms can distort decision-support outputs in risk modelling [63]. Hyperparameters were tuned on validation data and final estimates were computed once on the test set. Bootstrap confidence intervals quantified metric uncertainty and the DeLong test supported paired ROC-AUC comparison. Table 6 summarizes the protocol.
Performance gain over each baseline is defined in Equation (16).
Δ M b = M prop M b , G b = M prop M b | M b | + ϵ × 100 , Δ fair , b = Γ prop Γ b
Here, M prop and M b are proposed-model and baseline scores, Δ M b is the absolute difference, G b is percentage gain and Δ fair , b is the fairness-gap difference. For Brier score and ECE, lower values indicate better performance.

3.9. Cross-Dataset Evaluation Protocol

External generalization was tested using the HackerEarth Employee Burnout Challenge dataset as an independent occupational burnout cohort with the OSMI survey serving as the development dataset. The external cohort includes train.csv with 22,750 records and 9 variables and test.csv with 12,250 records and 8 variables, covering employee identifier, joining date, gender, company type, work-from-home setup, designation, resource allocation, mental fatigue score and Burn Rate. Because the OSMI and HackerEarth datasets used different survey instruments, external evaluation used conceptual feature harmonization rather than direct item-level matching. Variables were aligned only when they represented comparable occupational-health domains, including demographics, employment context, work arrangement, workload intensity, fatigue or stress burden and support-related proxies. Features without a defensible conceptual counterpart were excluded from the main harmonized model and retained only for sensitivity analysis. The continuous HackerEarth Burn Rate was converted into a binary high-risk label using the upper tertile of the training distribution with a 0.50 threshold used as a sensitivity check.
Table 7 summarizes source-only transfer, target-only baseline, pooled learning, target-adapted fine-tuning, feature harmonization, label conversion, calibration transfer and fairness checks. All settings followed Section 3.2, Section 3.4 and Section 3.6. The transfer-learning procedure had four stages: source-model training on OSMI, direct evaluation on the harmonized HackerEarth representation to quantify source-only transfer under dataset shift, target adaptation using labelled HackerEarth training data with regularization toward the source solution and target recalibration plus test evaluation using discrimination, calibration and fairness metrics. This design evaluates whether broad occupational risk signals can transfer after harmonization and recalibration without claiming that OSMI mental-health items and HackerEarth burnout variables are identical measurements or that source-only results are deployment-ready evidence.
The external burnout label is defined in Equation (17).
y i HE = I b i Q 0.67 B train
Here, y i HE is the high-burnout label, b i is Burn Rate and Q 0.67 ( B train ) is the training-set 67th percentile. The cross-dataset adaptation objective is defined in Equation (18).
Θ OSMI HE * = arg min Θ L OSMI Θ ; D OSMI + λ HE L HE Θ ; D HE train + λ m MMD 2 H OSMI , H HE + λ c ECE OSMI ECE HE
Here, Θ OSMI HE * is the adapted model, L OSMI and L HE are source and target losses, MMD aligns hidden representations and the ECE term controls calibration consistency. External generalization is summarized by Equation (19).
Δ CD = A within A cross + ω e ECE cross ECE within + ω g Γ cross Γ within
Here, Δ CD is the degradation score, A is AUC, ECE is calibration error, Γ is the fairness gap and ω e , ω g weight calibration and fairness degradation.

3.10. Hardware and Software Environment

To improve reproducibility, all experiments were implemented in a controlled Python 3.10.12 environment. environment using fixed random seeds, stratified train–validation–test splits and deterministic backend settings where available. The same hardware and software stack was used for the proposed model and all baselines, including preprocessing, attention-based tabular modelling, VAE latent profiling, ensemble learning, calibration, interpretability analysis and transfer evaluation. The computational environment is summarized in Table 8 and package versions, configuration files and experiment logs were retained for replication.

4. Results

This section reports the empirical findings produced by the proposed methodological pipeline. The results are presented in the same workflow order as the methodology, covering calibration, discrimination, baseline comparison, interpretability, latent profiling, fairness assessment, cross-region transfer and external cross-dataset evaluation. This organization ensures that the reported evidence follows a coherent sequence from model development and validation to interpretability, subgroup analysis, transfer evaluation and external dataset assessment. Throughout this section, the findings are interpreted as evidence for occupational mental-health risk modelling from heterogeneous workplace survey data with relevance to knowledge-work settings rather than as direct empirical measurement of early-career academic populations.

4.1. Calibration, Threshold Performance and Risk-Index Mapping

Table 9 evaluates whether the calibrated probabilities produced by Equation (7) correspond to observed outcome frequencies and can therefore support an interpretable risk-index scale. The calibration bins show close alignment between mean predicted probability and observed fraction positive across the full probability range. In the lowest bin, the mean predicted probability is 0.069575, while the observed fraction positive is 0.076923 across 78 respondents. This indicate that the model does not substantially inflate low-risk estimates, in the intermediate range the 0.20–0.50 bin have a mean prediction of 0.358531 and also an observed fraction positive of 0.422222 across 45 respondents, showing modest underestimation among ambiguous cases. The 0.50–0.80 bin shows stronger agreement with predicted probability 0.688924 and observed fraction positive 0.693877 across 49 respondents. The highest-risk bin remains practically well-calibrated with mean prediction 0.886547 and observed fraction positive 0.862500 across 80 respondents.
Thesame table also reports strong discrimination with AUC ROC = 0.88199 and average precision = 0.86884. These values shows that calibration did not remove the ranking strength needed to identify respondents with elevated occupational mental-health support needs. The calibrated probabilities are then mapped into a 0–100 risk index and four operational risk bands. Very low risk corresponds to scores 1.6–11.2, low risk to 11.2–55.4, moderate risk to 55.4–85.8 and high risk to 85.8–96.3. This mapping converts probabilistic model outputs into an operational scale that can support monitoring, outreach prioritization and further assessment, while remaining distinct from a clinical diagnosis.

4.2. Predictive Discrimination and Attention-Based Interpretability

Figure 6 summarizes discrimination across the evaluated baseline and proposed models using the precision–recall and ROC protocols defined in Table 4. The precision–recall curves show that several models retrieve positive cases effectively with the strongest models reaching average precision values near 0.87. This result is important because the positive class represents respondents with elevated likelihood of occupational mental-health support need. Precision–recall performance therefore provides a more relevant view of elevated-risk retrieval than accuracy alone. The ROC curves show similarly strong separation between positive and negative cases with leading models reaching AUC values near 0.88. The curves are relatively clustered, indicating that multiple tabular learning methods are competitive under the same preprocessing, splitting and validation protocol.
The proposed attention-based risk model remains among the strongest performers, supporting the representation and prediction logic in Equations (4) and (5). Taken together, the two panels suggests that the model still preserves ranking quality while keeping strong retrieval of likely high-risk respondents. This supports using calibrated predictions as the basis for downstream risk indexing, latent-profile analysis, perturbation testing and fairness evaluation. Figure 7 provides an interpretability check for the attention module. The highest attention concentration appears around work_interfere, indicating that the model learns a focused dependency structure instead of spreading importance evenly across every input. This result agrees with the later perturbation findings, where work interference produces the largest performance drop when it is disrupted.

4.3. State-of-the-Art Baseline Comparison

Table 10 provides the main comparative evaluation because it directly tests the proposed attention-VAE-ensemble RI model against linear, kernel, tree-based, boosting and deep tabular baselines. The comparison follows the baseline protocol in Section 3.8 and uses the gain logics in Equation (16). The proposed model achieves the best overall discrimination with AUC = 0.885, AP = 0.872 and F1 = 0.808. Random forest is the closest conventional comparator with AUC = 0.882, AP = 0.859 and F1 = 0.802. CatBoost is also competitive with AUC = 0.881, AP = 0.860 and F1 = 0.801. The proposed model therefore gives modest AUC gains but clearer improvement in average precision and F1.
The calibration and fairness columns are especially important because the proposed framework is intended for responsible risk scoring rather than discrimination alone. The proposed model achieves the lowest Brier score, 0.145, and the lowest ECE, 0.022. CatBoost is the closest calibrated baseline with Brier = 0.148 and ECE = 0.030, while random forest has Brier = 0.153 and ECE = 0.039. The proposed model also gives the smallest fairness gap, 0.169, compared with 0.184 for CatBoost, 0.181 for FT–Transformer and 0.206 for random forest. These results indicate that the proposed framework improves probability reliability and subgroup consistency in addition to maintaining competitive discrimination.

4.4. Interaction Structure, Perturbation Sensitivity and Cross-Validation Stability

Figure 8 and Figure 9, and Table 11 evaluate whether the proposed model relies on stable and interpretable feature relationships. The interaction heatmap shows clustered dependencies among occupational, demographic and support-related variables, indicating that the model does not distribute importance uniformly across all inputs. Instead, several feature groups form localized interaction patterns, supporting attention-guided hidden-pattern discovery in heterogeneous behavioural data. This interpretation is conceptually consistent with attention-enhanced abnormal-pattern identification methods in other complex data domains, where deep representation learning and attention mechanisms have been used to detect subtle hidden signals and improve robustness under difficult distributional conditions [16].
The strongest listed interaction effects involve work_int with anon and gender with remote, both with interaction values of 0.009. The gender-remote interaction is statistically significant with p = 0.020 and the country-mh_intervw interaction is also significant with p = 0.020 . These results suggest that risk prediction is influenced not only by individual features but also by contextual relationships between work arrangement, demographic background and help-seeking attitudes.
Perturbation analysis further confirms the importance of work interference. When work_int is perturbed, AUC decreases from 0.844 to 0.657, corresponding to a 22.1% relative reduction. In contrast, perturbing stress, support, country and anon produces only minor changes in AUC, suggesting that these variables are either more redundant with other predictors or less individually decisive under the perturbation protocol.
The cross-validation results in Table 11 should be interpreted as a robustness analysis rather than as the main held-out benchmark comparison. The fixed held-out baseline-comparison experiment reports the final proposed-model performance under one predefined test partition, whereas the five-fold cross-validation results summarize performance variability across multiple train–test partitions. Therefore, the fixed held-out AUC of 0.885 and the five-fold mean test AUC of 0.809 ± 0.044 are not contradictory; they represent different validation settings. The lower cross-validation mean provides a more conservative estimate of generalization and indicates moderate sensitivity to data partitioning. Across folds, validation AUC remains 0.846 ± 0.019 , validation AP remains 0.794 ± 0.035 , test AUC is 0.809 ± 0.044 and test F1 is 0.746 ± 0.057 .

4.5. Latent Behavioural Profiles and Synthetic Validity

Table 12 and Table 13 summarize the latent profile results from the VAE-GMM procedure in Equations (8) and (9). Two occupational–behavioural profiles are identified. Cluster C 0 is characterized by rare work interference, smaller organizations, positive coworker support, positive supervisor support and lower average risk. Cluster C 1 shows more frequent work interference, larger organizations, partial coworker support, weaker supervisor support and higher average risk. The cluster summary confirms this difference with Cluster 0 containing 649 respondents and average risk 0.448, while Cluster 1 contains 610 respondents and average risk 0.487. The visual panels support this interpretation by showing higher risk spread in Cluster 1 and partial latent-space separation with boundary mixing.
Synthetic validity is mixed and should be interpreted conservatively. Random forest baseline performance is AUC = 0.882 and AP = 0.859, while the augmented version gives AUC = 0.879 and AP = 0.864. This suggests that synthetic augmentation slightly improves ranking precision but does not improve overall discrimination. Continuous-variable fidelity is weaker, especially for age with KS = 0.778 and EMD = 1.2 × 10 8 and stress_score with KS = 0.589 and EMD = 0.530. Categorical variables show more reasonable agreement, indicating that synthetic records are more defensible for robustness checks than for unrestricted replacement of real workplace observations.

4.6. Feature Ablation, Subgroup Fairness and Regional Transfer

Figure 10, and Table 14 and Table 15 evaluate whether the models are driven by plausible occupational signals and whether reliability varies across subgroups and regions. The ablation results show that stress_score is the dominant individual predictor because its removal reduces AUC by 0.114. The next strongest effects are work_interfere_enc and care_options_enc, each reducing AUC by 0.020, while benefits_enc has a smaller effect of −0.007. These values agree with the attention and perturbation findings, confirming that stress burden, work interference and care access are central model drivers.
The subgroup results show uneven country-level reliability. Germany has the highest listed subgroup AUC at 0.903, followed by the United Kingdom at 0.880 and the United States at 0.868. Canada is lower at 0.734, indicating a meaningful subgroup performance gap that should not be hidden by aggregate metrics. The regional transfer table further supports this conclusion. The United States has self-transfer AUC = 0.698 and mean cross-region AUC = 0.637, while Germany has self-transfer AUC = 0.677 and mean cross-region AUC = 0.579. The United Kingdom performs weakly in self-transfer with AUC = 0.465 and only modestly as a source with mean cross-region AUC = 0.492. These findings support local recalibration, subgroup reporting and source-to-target adaptation as defined in Equation (12).

4.7. Cross-Dataset Evaluation on the HackerEarth Burnout Dataset

Table 16 reports the external cross-dataset evaluation using the independent HackerEarth Employee Burnout Challenge dataset. The experiment follows the harmonization and adaptation protocol in Section 3.9. Source-only transfer performs weakly with AUC = 0.642, AP = 0.617, ECE = 0.128 and fairness gap = 0.214. This confirms substantial dataset shift and shows that direct deployment of the OSMI-trained source model would be unreliable without target-domain adaptation. Source calibration alone does not improve ranking and slightly worsens ECE to 0.132, while target recalibration reduces ECE to 0.052 but leaves AUC and AP unchanged at 0.642 and 0.617.
Target-aware models perform substantially better. The target-only baseline reaches AUC = 0.932, AP = 0.925, ECE = 0.041 and fairness gap = 0.092. Pooled learning remains strong but slightly weaker with AUC = 0.919 and AP = 0.913, suggesting that source-domain data add coverage but may dilute target-specific signals. Target-adapted fine-tuning improves performance to AUC = 0.935, AP = 0.929, ECE = 0.038 and fairness gap = 0.086. The final harmonized and adapted OSMI-HackerEarth model performs best overall, achieving AUC = 0.941, AP = 0.936, ECE = 0.029 and fairness gap = 0.078. These results support the cross-dataset objective in Equation (18), showing that external performance is strongest when conceptual harmonization, target labels, calibration control and adaptation are combined. The findings should therefore be interpreted as evidence for transferable occupational risk modelling after target-domain adaptation, not as evidence that an OSMI-only model generalizes directly to all occupational burnout settings.

5. Discussion and Comparison

Table 17 compares the proposed framework with recent studies that address occupational stress, burnout, sickness absence associated with mental disorders and explainable workplace mental-health prediction. The comparison indicates that contemporary research increasingly integrates survey-based workplace data with machine-learning models, explainability techniques and empirical validation procedures. In relation to these studies, the proposed framework provides a broader occupational mental-health modelling system by jointly incorporating calibrated risk-index mapping, attention-based tabular learning, VAE-GMM latent profiling, subgroup fairness assessment and cross-dataset transfer validation. This comparison positions the study as a general occupational risk-modelling contribution with relevance to high-pressure knowledge-work settings, including but not limited to early-career academic contexts.

5.1. Predictive Performance, Calibration and Risk-Index Utility

The proposed model demonstrates competitive predictive performance against recent occupational and workplace mental-health prediction studies while also adding calibrated risk-index utility for decision support. In Table 10, the proposed attention-VAE-ensemble RI model achieves AUC = 0.885, AP = 0.872 and F1 = 0.808, which places it above random forest, CatBoost, LightGBM, XGBoost and deep tabular baselines under the same evaluation protocol. The AUC gain over random forest is small because random forest already reaches AUC = 0.882, yet the proposed model improves AP from 0.859 to 0.872 and F1 from 0.802 to 0.808, which is important because AP better reflects retrieval of respondents with elevated support needs.
Recent studies report similar aggregate discrimination, although they usually emphasize classification performance more than calibrated decision support. Hasan et al. reported ensemble accuracy of 90.32% for occupational stress detection, which confirms the usefulness of ensemble learning for workplace stress prediction [71]. Jeong et al. reported random forest ROC-AUC = 0.904 for burnout-syndrome risk prediction using KOSS variables, which further shows that structured occupational indicators can produce strong discrimination [72]. Mokheleli et al. reported XGBoost accuracy = 91% and ROC-AUC = 90% using OSMI workplace mental-health data, which provides another relevant benchmark for workplace mental-health prediction [34].
The main distinction of the present study is that Table 9 converts predicted probabilities into calibrated risk bands with AUC ROC = 0.88199, AP = 0.86884, Brier score = 0.145 and ECE = 0.022. This calibration layer makes the model more suitable for institutional decision support because probability reliability is needed before assigning low, moderate or high outreach categories. The resulting risk index should therefore be interpreted as an operational support-prioritization tool rather than as a diagnostic instrument.

5.2. Interpretability, Latent Profiles and Occupational Risk Mechanisms

The interpretability results indicate that the proposed framework identifies plausible occupational mechanisms rather than only maximizing aggregate accuracy. Figure 7 shows that attention is concentrated around work_interfere, while Table 11 confirms that perturbing work_int reduces AUC from 0.844 to 0.657, which corresponds to a 22.1% performance loss. Table 14 independently supports this pattern by showing that stress_score causes the largest ablation decline with Δ AUC = −0.114, followed by work_interfere_enc and care_options_enc, each with Δ AUC = −0.020. These findings are consistent with occupational mental-health theory because stress burden, work interference and care access are expected to shape perceived need for support.
Recent related studies also emphasize interpretability, although most rely mainly on post hoc feature attribution without latent behavioural profiling. Hasan et al. used LIME and SHAP to explain occupational stress predictions, which supports the value of local and global explanation methods in this domain [71]. Jeong et al. used SHAP to identify job instability and lack of reward as major burnout predictors, which aligns with the importance of occupational structure in mental-health risk prediction [72]. Mokheleli et al. used SHAP and LIME to interpret OSMI workplace mental-health predictions, where treatment and mental-disorder history variables were identified as influential predictors [34].
The present study extends this interpretability layer through Table 12 and Figure 8, which show two latent occupational–behavioural profiles with different support and stress patterns. Cluster 1 has higher average risk than Cluster 0 with risk values of 0.487 versus 0.448, suggesting graded workplace risk configurations rather than rigid diagnostic categories. This profiling component is useful for organizational interpretation because a probability score may indicate elevated risk, while latent profiles help explain whether that risk is associated mainly with work interference, limited support, care-access barriers or related workplace conditions. For high-pressure knowledge-work environments, including academic institutions, this distinction matters because preventive responses may require organizational changes rather than only individual recommendations.
Table 17. Comparison with recent occupational stress, burnout and OSMI-based mental-health prediction studies.
Table 17. Comparison with recent occupational stress, burnout and OSMI-based mental-health prediction studies.
StudyData/OutcomeModelResultResponsible-AI ElementsComparison with Proposed Study
Hasan et al. [71]Workplace stress surveyEnsemble ML, 1D-CNN, LLMAccuracy = 90.32%; unseen = 89%LIME, SHAP, ablationStress-focused but no RI bands or transfer testing
Jeong et al. [72]KOSS burnout data; 1205 workersFive ML modelsRF ROC-AUC = 0.904SHAP, stressor thresholdsStrong burnout benchmark but no latent profiling or transfer validation
Iwasaki et al. [73]Job-stress data; LTSA riskML with samplingAP = 0.040; ROC-AUC = 0.81Imbalance handling, longitudinal validationShows rare-event difficulty; lacks RI and subgroup calibration
Mokheleli et al. [34]OSMI workplace mentalhealth dataRF, XGBoost, SVM, AdaBoostXGBoost accuracy = 91%; ROC-AUC = 90%SHAP, LIME, SMOTEClosest OSMI comparator; no RI, VAE or transfer evaluation
Younis [74]OSMI; treatment willingnessRF, GB, SVM, KNN, LRBest accuracy = 0.83ML comparisonSame OSMI source but no calibration, fairness or external validation
Priyanka et al. [75]OSMI Mental Health in Tech surveys; 2016–2023Multi-scale 1D-CNN, channel-wise attention, XGBoost ensembleAccuracy = 91.54%; F1 = 92%; precision = 92%; recall = 91%SHAP, attention-based feature learning, local/global interpretabilityStrong deep-XAI comparator; lacks RI bands, VAE latent profiling, calibration and transfer validation
Chen et al. [76]OSMI 2014; work-interfering mental-health risk; 1259 recordsLR, DT, RF, Gradient BoostingRF recall = 0.878; F1 = 0.803; accuracy = 0.737Gender fairness audit, feature analysis, recall-focused evaluationSame OSMI source and fairness-oriented, but no RI bands, calibration, VAE profiling or external validation
Hendrick [77]OSMI; mental-health disorder classificationRF, XGBoostAccuracy gain: RF = 1.67%; XGBoost = 0.67%Expert feature selectionSame OSMI source; no RI bands, VAE profiles or transfer testing
Mokheleli [78]OSMI; age-stratified risk predictionRF, XGBoost, SVMRF/XGBoost accuracy = 91%; F1 = 93%SHAP, age-stratified analysisStrong subgroup interpretation; lacks calibration and cross-dataset validation
Othman and Rosdi [79]OSMI 2014; treatment seekingDecision Tree, KNNDT accuracy = 73%; KNN = 100%Interpretable classifiersSame OSMI target; limited responsible-AI and transfer evaluation
Proposed studyOSMI plus HackerEarth burnout validationAttention-VAE-ensemble RI modelAUC = 0.885; AP = 0.872; ECE = 0.022; external AUC = 0.941Calibration, attention, VAE, fairness, transferUnified prediction, calibration, profiling, fairness and adaptation framework
Note: RI = risk index; OSMI = Open Sourcing Mental Illness; AP = average precision; ECE = expected calibration error; LTSA = long-term sickness absence; VAE = variational autoencoder; RF = random forest; GB = gradient boosting; LR = logistic regression.

5.3. Fairness, Transferability and External Generalization

The fairness and transfer results show that strong aggregate performance does not remove the need for subgroup-specific validation. Table 10 reports the smallest fairness gap for the proposed model with fairness gap = 0.169, compared with 0.184 for CatBoost, 0.181 for FT–Transformer and 0.206 for random forest. Table 14 also shows country-level subgroup variation with AUC = 0.903 for Germany, 0.880 for the United Kingdom, 0.868 for the United States and 0.734 for Canada. These differences indicate that aggregate model quality can conceal regional reliability gaps, especially when subgroup sizes, reporting norms, care-access conditions and occupational contexts differ.
Transfer learning further confirms the importance of adaptation before deployment because regional portability remains uneven across available partitions. Table 15 shows that United States models transfer better than several smaller sources with self AUC = 0.698 and mean cross-region AUC = 0.637. By contrast, the United Kingdom has self AUC = 0.465 and mean cross-region AUC = 0.492, which suggests weak portability under the available regional partition. This concern is consistent with Iwasaki et al., who found that predicting rare long-term sickness absence due to mental disorders remained difficult even with a large occupational cohort, reporting AP = 0.040 and ROC-AUC = 0.81 [73].
Table 16 provides an additional external test using the HackerEarth burnout dataset. Direct source-only transfer from OSMI is weak with AUC = 0.642 and ECE = 0.128, which confirms substantial dataset shift. In contrast, the final harmonized and adapted model reaches AUC = 0.941, AP = 0.936, ECE = 0.029 and fairness gap = 0.078, showing that cross-dataset occupational risk modelling becomes more reliable when conceptual harmonization, target labels, recalibration and adaptation are used together. These findings should not be interpreted as evidence that an OSMI-trained model can be deployed directly in any occupational or academic setting without local validation.
Overall, the discussion supports three connected conclusions about calibrated occupational mental-health risk modelling. First, calibrated risk indexing improves practical interpretability by converting probabilities into operational risk bands for support prioritization. Second, attention analysis, perturbation testing and latent profiling provide convergent evidence that the model relies on plausible occupational signals, especially stress burden, work interference and care-access variables. Third, subgroup and transfer results show that responsible use requires local validation, recalibration and fairness monitoring before deployment in new workplace settings. These requirements are especially important if the framework is later applied to early-career academics or other high-pressure knowledge-work populations because the present empirical datasets represent broader workplace cohorts rather than direct ECR-only samples.

6. Conclusions and Future Work

In conclusion, this study developed an interpretable deep-learning framework for occupational mental-health risk modelling using heterogeneous workplace survey data. The proposed approach combined attention-based tabular learning, calibrated probability mapping, latent occupational–behavioural profiling, ensemble prediction, fairness assessment and transfer validation within a single computational pipeline. The framework was motivated by the need for risk-modelling tools that are relevant to high-pressure knowledge-work populations, including early-career academic communities, while the empirical development and validation were conducted on broader workplace mental-health and burnout datasets.
Quantitatively, the proposed attention-VAE-ensemble risk-index model achieved strong held-out performance with AUC = 0.885, average precision = 0.872 and F1 = 0.808, outperforming logistic regression, support vector machine, random forest, XGBoost, LightGBM, CatBoost, TabNet, FT–Transformer, NODE and DCN under the same evaluation protocol. The model also produced reliable calibrated risk estimates with Brier score = 0.145 and expected calibration error = 0.022, supporting the conversion of calibrated probabilities into operational 0–100 risk-index scores. Robustness analysis showed a conservative five-fold mean test AUC of 0.809 ± 0.044 , indicating moderate sensitivity to data partitioning but stable predictive utility across repeated validation. External cross-dataset evaluation on the occupational burnout cohort further demonstrated practical generalization after harmonization, target-domain adaptation and recalibration, achieving AUC = 0.941 and average precision = 0.936. These results indicate that the framework is effective not only for discrimination but also for calibrated risk stratification, subgroup-aware interpretation and transfer-oriented occupational mental-health decision support. Key predictors such as work_interfere and stress_score were consistently identified across attention, ablation and perturbation analyses, while latent profiling revealed distinct occupational–behavioural subgroups with different support, stress and work-interference patterns.
The findings also highlight important limitations that should guide future development. Subgroup and transfer analyses showed that model performance can vary across countries and demographic groups, indicating that aggregate accuracy is insufficient for responsible institutional deployment. Fairness gaps, subgroup calibration differences and weaker transfer in smaller or more heterogeneous regions suggest that future implementations should include local validation, subgroup-aware calibration and bias-mitigation procedures before practical use. The cross-dataset evaluation further showed that direct source-only transfer is unreliable under dataset shift, whereas harmonization, target-domain labels, recalibration and adaptation substantially improve external performance. Synthetic data experiments also showed mixed fidelity, especially for continuous variables, meaning that generated records should remain restricted to robustness checks unless stronger distributional validation is achieved.
Future work should extend the framework using longitudinal academic workforce data to capture temporal changes in stress, support availability, workload pressure, mentoring access and help-seeking behaviour. Such data would allow the framework to be tested directly in early-career academic populations rather than inferred from broader workplace cohorts. Additional work should examine domain-adaptation methods, fairness-aware thresholding and causal validation strategies to improve reliability across institutions, countries and career stages. Integrating multimodal information, including workload logs organizational policy indicators, mentoring availability and repeated well-being assessments, may further strengthen predictive accuracy while preserving interpretability. From a practical perspective, the reported AUC, average precision, calibration error and external-validation results suggest that the proposed framework can support preventive outreach prioritization, provided that local validation, recalibration and fairness monitoring are conducted before deployment.

Author Contributions

Conceptualization, A.K.; methodology, A.J.; software, A.J.; validation, K.R.; formal analysis, A.I.; investigation, M.F.S.; resources, G.H.; data curation, A.K.; writing—original draft preparation, A.J.; writing—review and editing, M.I.M.; visualization, K.R.; supervision, G.H.; project administration, M.I.M.; funding acquisition, A.I. All authors have read and agreed to the published version of the manuscript.

Funding

This work was supported by the Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia Grant No. KFU262728.

Institutional Review Board Statement

Ethical review and approval were not required because this study used only publicly available, de-identified secondary datasets and involved no direct contact with human participants. The datasets used were the OSMI Mental Health in Tech Survey dataset, available at https://www.kaggle.com/datasets/osmi/mental-health-in-tech-survey (accessed on 24 April 2026) and the HackerEarth Employee Burnout Challenge dataset, available at https://www.kaggle.com/datasets/redwankarimsony/hackerearth-employee-burnout-challenge (accessed on 24 April 2026).

Informed Consent Statement

Not applicable. This study used publicly available, de-identified secondary datasets and no informed consent was obtained by the authors for this secondary analysis.

Data Availability Statement

The datasets used in this study are publicly available on Kaggle. Dataset A is the OSMI Mental Health in Tech Survey, available at Dataset A Link: https://www.kaggle.com/datasets/osmi/mental-health-in-tech-survey (accessed on 24 April 2026). Dataset B is the HackerEarth Employee Burnout Challenge dataset, available at Dataset B Link: https://www.kaggle.com/datasets/redwankarimsony/hackerearth-employee-burnout-challenge (accessed on 24 April 2026). All code used for data preprocessing, model training, evaluation and figure generation is available at Code Link: https://github.com/abuzarkhaaan/Deep-Learning-Based-Predictive-Modeling- (accessed on 15 November 2025). The repository includes configuration files and scripts to reproduce the main results reported in this paper.

Conflicts of Interest

The authors declare no conflicts of interest.

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Figure 1. Conceptual illustration of stress-related brain activation differences between (a) moderate-stress and (b) high-stress conditions. The red-colored regions indicate brain areas showing stress-related activation differences, with more extensive red regions representing higher activation differences under the high-stress condition. Adapted from neuroimaging findings by Choi and Choi [4].
Figure 1. Conceptual illustration of stress-related brain activation differences between (a) moderate-stress and (b) high-stress conditions. The red-colored regions indicate brain areas showing stress-related activation differences, with more extensive red regions representing higher activation differences under the high-stress condition. Adapted from neuroimaging findings by Choi and Choi [4].
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Figure 3. Overall study flow of the proposed occupational mental-health risk-modelling framework showing preprocessing, calibrated prediction, stress-phenotype discovery, explainability, fairness assessment and final decision-support outputs.
Figure 3. Overall study flow of the proposed occupational mental-health risk-modelling framework showing preprocessing, calibrated prediction, stress-phenotype discovery, explainability, fairness assessment and final decision-support outputs.
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Figure 4. Mathematical overview of the proposed attention-based tabular learning framework. Arrows show data flow, colors distinguish the main framework modules, and ellipses indicate repeated tokens or components shown schematically for compactness.
Figure 4. Mathematical overview of the proposed attention-based tabular learning framework. Arrows show data flow, colors distinguish the main framework modules, and ellipses indicate repeated tokens or components shown schematically for compactness.
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Figure 6. Precision–recall and ROC curves summarising predictive performance across evaluated model families, with overlapping curve segments indicating comparable model behaviour. (a) Precision–recall curve for evaluated baseline and proposed occupational risk models. (b) ROC curve for evaluated baseline and proposed occupational risk models.
Figure 6. Precision–recall and ROC curves summarising predictive performance across evaluated model families, with overlapping curve segments indicating comparable model behaviour. (a) Precision–recall curve for evaluated baseline and proposed occupational risk models. (b) ROC curve for evaluated baseline and proposed occupational risk models.
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Figure 7. Average attention matrix showing feature-dependency structure learned by the tabular model.
Figure 7. Average attention matrix showing feature-dependency structure learned by the tabular model.
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Figure 8. Cluster-level risk distributions and latent-space separation across inferred behavioural profiles. (a) Risk-score distribution across latent behavioural clusters identified by the GMM model. (b) Latent-space projection showing partial separation and boundary mixing across clusters.
Figure 8. Cluster-level risk distributions and latent-space separation across inferred behavioural profiles. (a) Risk-score distribution across latent behavioural clusters identified by the GMM model. (b) Latent-space projection showing partial separation and boundary mixing across clusters.
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Figure 9. Clustered interaction network heatmap showing reinforcing and compensatory feature relationships.
Figure 9. Clustered interaction network heatmap showing reinforcing and compensatory feature relationships.
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Figure 10. Ablation effects and fairness-related variation in predicted occupational mental-health risk. (a) Ablation analysis showing AUC changes after feature removal or perturbation. (b) Predicted risk distributions showing subgroup variation across gender categories, where the dots represent individual sample-level predicted risk values.
Figure 10. Ablation effects and fairness-related variation in predicted occupational mental-health risk. (a) Ablation analysis showing AUC changes after feature removal or perturbation. (b) Predicted risk distributions showing subgroup variation across gender categories, where the dots represent individual sample-level predicted risk values.
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Table 1. Comparison of related computational approaches for occupational and public mental health risk modelling.
Table 1. Comparison of related computational approaches for occupational and public mental health risk modelling.
Study TypeOccupational/ECR RelevanceTabular Health DataAttention-Based ModellingVAE/Latent ProfilingCalibrationInterpretabilityFairness/Subgroup EvaluationTransfer Validation
Public AI [38,67]×Δ×ΔΔΔ×
Academic MH [40,68,69]Δ×××ΔΔ×
General ML classifiers [42]Δ××ΔΔΔ×
Deep Tabular [46,52,70]××ΔΔ×Δ
Attention-based deep learning [16,48,49]Δ×ΔΔ×Δ
Responsible AI [58,59,64,65,66]×Δ×
Our studyΔ
Note: ✓ = fully addressed; Δ = partially addressed or addressed as a motivating/application context; × = not addressed or not central to the study. ECR = early-career researcher; VAE = variational autoencoder; MH = mental health; ML = machine learning.
Table 2. Dataset summary and analytical role.
Table 2. Dataset summary and analytical role.
AttributeDescription
Dataset nameMental Health in Tech Survey (Open Sourcing Mental Illness)
SampleWorking respondents from a workplace mental-health survey, used as a development cohort for occupational risk modelling
Sample sizeAround 1000–2000 respondents after filtering and cleaning
CoverageMulti-country sample, mainly North America and Europe
InputsDemographics, workplace factors, support, stigma, benefits, access to care and help-seeking attitudes
OutcomeBinary indicator of likely need for mental health support
Analytical roleSuitable for attention-based modelling, calibration, latent profiling, fairness checks and transfer evaluation
AccessPublic dataset, subject to repository and license terms
Table 3. Preprocessing, feature engineering and training protocol.
Table 3. Preprocessing, feature engineering and training protocol.
ComponentOperationImplementationPurpose
MissingnessMedian fill with masksTraining medians and binary indicatorsPreserve missingness without leakage
ScalingStandardizationTraining-set mean and standard deviationAlign numerical inputs
Categorical encodingInteger indexing and embeddingsTrainable embedding tablesRepresent sparse categories
Feature filteringVariance and correlation screeningLow-variance and redundancy filteringRemove unstable predictors
Composite featuresWorkload, support, barrier and access summariesWeighted survey-item aggregationCapture psychosocial constructs
Class imbalanceStratified splits and weighted focal lossNo oversampling in main trainingPreserve empirical distribution
OptimizerAdamW with Adam checksWarmup and cosine decayStabilize convergence
Batch and regularizationBatch size 64–128, dropout, weight decayHardware-dependent selectionReduce overfitting
Early stoppingValidation-loss monitoringPatience and best-weight restorationPrevent late-epoch overfitting
Table 4. Evaluation, latent validation, fairness assessment and transfer protocol.
Table 4. Evaluation, latent validation, fairness assessment and transfer protocol.
Evaluation Domain      MetricsProcedurePurpose
DiscriminationAUC and average precisionStratified test split and cross-validationEvaluate ranking and minority retrieval
CalibrationBrier score and expected calibration errorProbability-bin comparison and validation calibrationAssess probability reliability
Statistical testingBootstrap CI and DeLong testNon-parametric resampling for metric uncertainty and paired ROC-AUC comparison for model discriminationQuantify confidence intervals and statistical significance of performance differences
Latent validitySilhouette score and Davies–Bouldin indexMulti-seed VAE and GMM evaluationTest cluster stability
Synthetic validityKS distance and EMDReal-versus-synthetic comparisonDetect distribution mismatch
Interpretability stabilitySHAP rank agreement and perturbation AUC dropAttribution and masking testsEvaluate explanation robustness
FairnessSubgroup AUC, TPR gap, TNR gap and calibration gapRegion and demographic subgroup analysisIdentify uneven errors
Transfer learningSource-to-target fine-tuning and AUC dropTrain source, fine-tune targetAssess adaptation need
Baseline comparisonPooled global model and target-only modelMatched regional protocolBenchmark transfer results
Table 5. Hyperparameter selection and reproducibility controls.
Table 5. Hyperparameter selection and reproducibility controls.
ComponentParameter or ControlSelected ValueRole
TabTransformerEmbedding dimension32Dense categorical representation
TabTransformerAttention heads4Multi-context interaction learning
TabTransformerFeedforward width256Nonlinear transformation
TabNetDecision steps5Feature-selection depth
TabNetTransformer dimension64Representation width
VAELatent dimension16Behavioural profile representation
VAEKL weight β 0.5Reconstruction and regularization balance
EnsembleMeta-learner units64Prediction fusion capacity
EnsembleWeight regularization 1 × 10 3 Overfitting control
CalibrationPlatt scalingLearned on validation dataProbability reliability
RandomnessSeed controlFixed seed across splits and samplingReproducible comparison
DeterminismBackend settingsDeterministic operations where availableStable execution
VersioningPackage and environment recordsLocked versions with run logsEnvironment replication
HardwareGPU and CPU loggingRecorded per experimentPerformance traceability
Table 6. State-of-the-art baseline comparison protocol.
Table 6. State-of-the-art baseline comparison protocol.
Baseline FamilyModelsTuned ParametersPurpose
Linear and probabilistic modelsLogistic regression, ridge logistic modelRegularization strength, class weightTest calibrated linear structure
Kernel and margin modelsSupport vector machineKernel type, penalty, class weightTest nonlinear margins
Tree ensemblesRandom forest, extra treesTrees, depth, split size, class weightProvide non-neural tabular baselines
Gradient boostingXGBoost, LightGBM, CatBoostLearning rate, depth, estimators, leaf size, regularizationCompare against tabular SOTA methods
Deep tabular modelsTabNet, FT–Transformer, NODE, DCNEmbedding size, attention heads, decision steps, hidden widthCompare neural representation learning
Calibrated variantsPlatt-scaled and isotonic-calibrated baselinesCalibration method, validation splitCompare probability reliability
Proposed frameworkAttention-VAE-ensemble RI modelSettings from Table 5Evaluate integrated prediction, calibration, profiling and fairness validation
Table 7. Cross-dataset evaluation protocol using the HackerEarth Employee Burnout Challenge dataset.
Table 7. Cross-dataset evaluation protocol using the HackerEarth Employee Burnout Challenge dataset.
Evaluation SettingTraining DataTesting DataPurpose
Source-only transferOSMI survey onlyHackerEarth burnout datasetAssess external generalization
Target-only baselineHackerEarth training split onlyHackerEarth test splitEstimate local performance
Pooled learningOSMI plus HackerEarth harmonized training dataHackerEarth test splitTest shared occupational-risk signals
Target-adapted fine-tuningOSMI model plus small HackerEarth labelled subsetHackerEarth test splitAssess adaptation with limited labels
Feature-harmonized modelConceptually aligned variables onlyOSMI and HackerEarth test splitsEnsure defensible comparison
Burnout-label conversionHackerEarth Burn Rate converted to binary high-risk labelHackerEarth test splitAlign with risk classification
Calibration transferSource calibration and target recalibrationHackerEarth validation and test splitsEvaluate probability reliability
Fairness checkShared subgroup variables such as gender and work arrangementHackerEarth test splitExamine subgroup reliability
Table 8. Hardware and software environment used for model implementation and evaluation.
Table 8. Hardware and software environment used for model implementation and evaluation.
ComponentConfiguration
Operating systemUbuntu 22.04 LTS, 64-bit
Programming languagePython 3.10.14
Processorx86-64 workstation CPU
System memory32 GB RAM
Graphics processorNVIDIA GeForce RTX 3060
GPU memory12 GB VRAM
Deep-learning frameworkPyTorch 2.2.2
Machine-learning librariesScikit-learn 1.4.2, XGBoost 2.0.3, LightGBM 4.3.0, CatBoost 1.2.5
Data-processing librariesNumPy 1.26.4, Pandas 2.2.2
Interpretability toolsSHAP 0.45.1, integrated gradients and perturbation attribution
Calibration and evaluationROC-AUC, average precision, F1 score, Brier score and ECE
Reproducibility controlsFixed seeds, stratified splits, deterministic settings and experiment logs
Table 9. Calibration summary and risk-index mapping across probability bands and operational score levels.
Table 9. Calibration summary and risk-index mapping across probability bands and operational score levels.
Calibration by Probability Range
Prob RangeMean PredictedFraction PositiveCount
0.00 to 0.200.0695750.07692378
0.20 to 0.500.3585310.42222245
0.50 to 0.800.6889240.69387749
0.80 to 1.000.8865470.86250080
Overall Discriminative and Calibration Metrics
AUC ROCAverage Precision APBrier ScoreECE
0.881990.868840.1450.022
Risk Index Mapping
LabelProb RangeScore RangeNote
Very low0.00 to 0.251.6 to 11.2Conservative low-risk band
Low0.25 to 0.5011.2 to 55.4Increased monitoring
Moderate0.50 to 0.7555.4 to 85.8Outreach recommended
High0.75 to 1.0085.8 to 96.3Prioritized outreach and assessment
Table 10. Comparison with state-of-the-art baseline models across discrimination, calibration and fairness metrics.
Table 10. Comparison with state-of-the-art baseline models across discrimination, calibration and fairness metrics.
ModelAUCAPF1BrierECEFairness Gap
Logistic regression0.8290.7950.7240.1650.0340.176
Support vector machine0.8410.8070.7360.1770.0510.189
Random forest0.8820.8590.8020.1530.0390.206
XGBoost0.8760.8520.7900.1510.0340.195
LightGBM0.8790.8560.7970.1490.0320.190
CatBoost0.8810.8600.8010.1480.0300.184
TabNet0.8680.8400.7820.1580.0440.193
FT–Transformer0.8740.8480.7910.1540.0370.181
NODE0.8620.8330.7740.1600.0460.197
DCN0.8580.8270.7680.1630.0480.202
Proposed attention-VAE-ensemble RI model0.8850.8720.8080.1450.0220.169
Table 11. Feature interactions, perturbation sensitivity and five-fold cross-validation robustness analysis.
Table 11. Feature interactions, perturbation sensitivity and five-fold cross-validation robustness analysis.
Top Feature Interactions
Feat iFeat jInteractionp-ValueInterpretation
work_intanon0.0090.139Joint positive effect
genderremote0.0090.020Significant joint effect
countrymh_intervw0.0040.020Demographic-attitude link
work_intmh_consq−0.0090.931Weak negative association
Perturbation Impact on AUC
FeatureBase AUCPerturbed AUC Δ AUCInterpretation
work_int0.8440.657−22.1%Critical performance drop
stress0.8440.843−0.1%Negligible effect
support0.8440.842−0.2%Robust to perturbation
country0.8440.846+0.3%Mild sensitivity
anon0.8440.846+0.3%Possible redundancy
Cross-Validation Robustness Analysis, 5-fold
MetricMeanStdMinMax
Val AUC0.8460.0190.8260.873
Val AP0.7940.0350.7560.834
Test AUC0.8090.0440.7340.844
Test F10.7460.0570.6780.808
Table 12. Cluster centroids showing averaged categorical modes across two behavioural profiles.
Table 12. Cluster centroids showing averaged categorical modes across two behavioural profiles.
Feature C 0 C 1 Feature C 0 C 1
CountryUSUSseek_helpYesYes
stateCANYanonymityDKDK
self_emp.NoNoleaveSomewhatSomewhat
fam_histNoNomh_consqMaybeMaybe
work_intRarelyOftenph_consqNoMaybe
employees1–526–100coworkersYesSome
remoteYesYessupervisorYesNo
tech_coYesYesmh_intervwNoNo
benefitsNoNoph_intervwMaybeNo
care_optNoNomh_vs_phYesYes
wellnessNoNoobs_consqNoNo
Table 13. Evaluation summary covering downstream performance, latent clusters and synthetic validity checks.
Table 13. Evaluation summary covering downstream performance, latent clusters and synthetic validity checks.
Downstream Performance
ModelAUCAPMetrics
RF baseline0.8820.8590.816/0.802/0.771/0.867
RF augmented0.8790.8640.810/0.794/0.760/0.867
Cluster Summaries
ClusterSizeSignatureAvg risk
0649↑ support/↓ stress0.448
1610↓ support/↑ stress0.487
Synthetic vs. real
FeatureKSEMDVerdict
Age0.778 1.2 × 10 8 Divergent
stress_score0.5890.530Divergent
support_score0.3830.462Acceptable
Key categoricalssmall0.4–0.6Reasonable
Note: ↑ indicates a higher relative feature tendency within the cluster, whereas ↓ indicates a lower relative feature tendency.
Table 14. Ablation and subgroup fairness summary across influential features and regional groups.
Table 14. Ablation and subgroup fairness summary across influential features and regional groups.
Top Ablations ( Δ AUC)Selected Subgroup AUC
Feature Δ AUCSubgroupAUC
stress_score−0.114United States0.868
work_interfere_enc−0.020United Kingdom0.880
care_options_enc−0.020Germany0.903
benefits_enc−0.007Canada0.734
Table 15. Transfer learning performance across regions using self-transfer and cross-region AUC summaries.
Table 15. Transfer learning performance across regions using self-transfer and cross-region AUC summaries.
RegionSelf AUCMean Cross AUCBaseline AUC
United States0.6980.6370.449
United Kingdom0.4650.4920.510
Canada0.5370.5320.648
Germany0.6770.5790.670
Netherlands0.5940.5400.519
Ireland0.6000.5310.538
Table 16. Cross-dataset evaluation results using the HackerEarth Employee Burnout Challenge dataset.
Table 16. Cross-dataset evaluation results using the HackerEarth Employee Burnout Challenge dataset.
Training SettingDevelopment DataExternal Test DataAUCAPECEFairness Gap
Source-only transferOSMI surveyHackerEarth burnout dataset0.6420.6170.1280.214
Target-only baselineHackerEarth training splitHackerEarth test split0.9320.9250.0410.092
Pooled learningOSMI plus HackerEarth harmonized training dataHackerEarth test split0.9190.9130.0490.104
Target-adapted fine-tuningOSMI model plus HackerEarth labelled subsetHackerEarth test split0.9350.9290.0380.086
Source calibration onlyOSMI calibrated modelHackerEarth test split0.6420.6170.1320.214
Target recalibrationOSMI model recalibrated on HackerEarth validation dataHackerEarth test split0.6420.6170.0520.208
Proposed final cross- dataset modelHarmonized and adapted OSMI-HackerEarth modelHackerEarth test split0.9410.9360.0290.078
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Khan, A.; Rehman, K.; Junaid, A.; Iqbal, A.; Siddique, M.F.; Mohmand, M.I.; Husnain, G. Calibrated Deep-Learning Risk Indexing and Latent Behavioural Profiling for Occupational Mental-Health Risk Assessment. Bioengineering 2026, 13, 626. https://doi.org/10.3390/bioengineering13060626

AMA Style

Khan A, Rehman K, Junaid A, Iqbal A, Siddique MF, Mohmand MI, Husnain G. Calibrated Deep-Learning Risk Indexing and Latent Behavioural Profiling for Occupational Mental-Health Risk Assessment. Bioengineering. 2026; 13(6):626. https://doi.org/10.3390/bioengineering13060626

Chicago/Turabian Style

Khan, Abuzar, Khalid Rehman, Ahmad Junaid, Abid Iqbal, Muhammad Farooq Siddique, Muhammad Ismail Mohmand, and Ghassan Husnain. 2026. "Calibrated Deep-Learning Risk Indexing and Latent Behavioural Profiling for Occupational Mental-Health Risk Assessment" Bioengineering 13, no. 6: 626. https://doi.org/10.3390/bioengineering13060626

APA Style

Khan, A., Rehman, K., Junaid, A., Iqbal, A., Siddique, M. F., Mohmand, M. I., & Husnain, G. (2026). Calibrated Deep-Learning Risk Indexing and Latent Behavioural Profiling for Occupational Mental-Health Risk Assessment. Bioengineering, 13(6), 626. https://doi.org/10.3390/bioengineering13060626

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