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Commentary

Importance of Apolipoprotein A-I and A-II Composition in HDL and Its Potential for Studying COVID-19 and SARS-CoV-2

1
Medical Innovation Complex, Korea Research Institute of Lipoproteins, Daegu 41061, Korea
2
LipoLab, Yeungnam University, Gyeongsan 712-749, Korea
Academic Editor: William Cho
Medicines 2021, 8(7), 38; https://doi.org/10.3390/medicines8070038
Received: 2 May 2021 / Revised: 30 June 2021 / Accepted: 15 July 2021 / Published: 16 July 2021
The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I or other apolipoproteins did not. However, there has been no report to elucidate the putative role of apoA-II in the antiviral activity of HDL. View Full-Text
Keywords: COVID-19; SARS-CoV-2; high-density lipoproteins; apoA-I; apoA-II; glycation COVID-19; SARS-CoV-2; high-density lipoproteins; apoA-I; apoA-II; glycation
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MDPI and ACS Style

Cho, K.-H. Importance of Apolipoprotein A-I and A-II Composition in HDL and Its Potential for Studying COVID-19 and SARS-CoV-2. Medicines 2021, 8, 38. https://doi.org/10.3390/medicines8070038

AMA Style

Cho K-H. Importance of Apolipoprotein A-I and A-II Composition in HDL and Its Potential for Studying COVID-19 and SARS-CoV-2. Medicines. 2021; 8(7):38. https://doi.org/10.3390/medicines8070038

Chicago/Turabian Style

Cho, Kyung-Hyun. 2021. "Importance of Apolipoprotein A-I and A-II Composition in HDL and Its Potential for Studying COVID-19 and SARS-CoV-2" Medicines 8, no. 7: 38. https://doi.org/10.3390/medicines8070038

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