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Review
Peer-Review Record

Natural Products Induce Lysosomal Membrane Permeabilization as an Anticancer Strategy

Medicines 2021, 8(11), 69; https://doi.org/10.3390/medicines8110069
by Reginald Halaby
Reviewer 1:
Reviewer 2: Anonymous
Medicines 2021, 8(11), 69; https://doi.org/10.3390/medicines8110069
Submission received: 31 August 2021 / Revised: 3 November 2021 / Accepted: 8 November 2021 / Published: 10 November 2021
(This article belongs to the Special Issue PROTAC—From Bench to Bed)

Round 1

Reviewer 1 Report

The review entitled "Natural Products Induce Lysosomal Membrane  Permeabilization as an Anticancer Treatment" by Halaby is very well written and adresses an important piece of literature.

Authors may consider enlisting the executioner caspases the first time they mention it in the Review.

Author Response

Dear Reviewer, the revisions concerning the executioner caspases are indicated in red ink. Thank you for your helpful comments.

Reviewer 2 Report

The review is a good one. Author should recheck the literature to ensure Table 1 summarize all Natural products with anticancer properties related to lysosomal membrane permeabilization. 

 

Author Response

Dear Reviewer,

I have included additional natural products that induce LMP in cancer cells. The edits are in red ink in the manuscript and in Table 1. Thank you very much for your helpful comments.

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