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Regenerative Perspective in Modern Dentistry

Carol Davila University of Medicine and Pharmacy, Faculty of Dental Medicine, Histology and Cytology Division, Bucharest, 8 Eroilor Sanitari Blvd., RO-050474, Romania
Victor Babeș National Institute of Pathology, Radiobiology Laboratory, Bucharest, Romania
Academic Editor: Ana Angelova Volponi
Dent. J. 2016, 4(2), 10;
Received: 24 February 2016 / Revised: 16 April 2016 / Accepted: 21 April 2016 / Published: 25 April 2016
(This article belongs to the Special Issue Craniofacial Biology for Tooth Repair and Regeneration)
PDF [215 KB, uploaded 25 April 2016]


This review aims to trace the contour lines of regenerative dentistry, to offer an introductory overview on this emerging field to both dental students and practitioners. The crystallized depiction of the concept is a translational approach, connecting dental academics to scientific research and clinical utility. Therefore, this review begins by presenting the general features of regenerative medicine, and then gradually introduces the specific aspects of major dental subdomains, highlighting the progress achieved during the last years by scientific research and, in some cases, which has already been translated into clinical results. The distinct characteristics of stem cells and their microenvironment, together with their diversity in the oral cavity, are put into the context of research and clinical use. Examples of regenerative studies regarding endodontic and periodontal compartments, as well as hard (alveolar bone) and soft (salivary glands) related tissues, are presented to make the reader further acquainted with the topic. Instead of providing a conclusion, we will emphasize the importance for all dental community members, from young students to experienced dentists, of an early awareness rising regarding biomedical research progress in general and regenerative dentistry in particular. View Full-Text
Keywords: regenerative dentistry; stem cells; translational medicine regenerative dentistry; stem cells; translational medicine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Nicolescu, M.I. Regenerative Perspective in Modern Dentistry. Dent. J. 2016, 4, 10.

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