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Open AccessArticle

Wide-Field OCT Angiography at 400 KHz Utilizing Spectral Splitting

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Center of Biomedical Engineering and Physics, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria
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Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Austria
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Institute of Applied Physics, Technical University Vienna, Wiedner Hauptstraße 8-10/E134, A-1040 Vienna, Austria
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Carl Zeiss Meditec, Inc., 5160 Hacienda Drive, Dublin, CA 94568, USA
*
Author to whom correspondence should be addressed.
Photonics 2014, 1(4), 369-379; https://doi.org/10.3390/photonics1040369
Received: 6 September 2014 / Revised: 15 October 2014 / Accepted: 15 October 2014 / Published: 23 October 2014
(This article belongs to the Special Issue Optics and Technologies for Ophthalmology and Visual Science)
Optical angiography systems based on optical coherence tomography (OCT) require dense sampling in order to maintain good vascular contrast. We demonstrate a way to gain acquisition speed and spatial sampling by using spectral splitting with a swept source OCT system. This method splits the recorded spectra into two to several subspectra. Using continuous lateral scanning, the lateral sampling is then increased by the same factor. This allows increasing the field of view of OCT angiography, while keeping the same transverse resolution and measurement time. The performance of our method is demonstrated in vivo at different locations of the human retina and verified quantitatively. Spectral splitting can be applied without any changes in the optical setup, thus offering an easy way to increase the field of view of OCT in general and in particular for OCT angiography. View Full-Text
Keywords: optical coherence tomography (OCT); retinal angiography; optical angiography; speckle variance OCT (SV OCT); swept source OCT (SS OCT); field of view (FOV); Doppler OCT (DOCT) optical coherence tomography (OCT); retinal angiography; optical angiography; speckle variance OCT (SV OCT); swept source OCT (SS OCT); field of view (FOV); Doppler OCT (DOCT)
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Ginner, L.; Blatter, C.; Fechtig, D.; Schmoll, T.; Gröschl, M.; Leitgeb, R.A. Wide-Field OCT Angiography at 400 KHz Utilizing Spectral Splitting. Photonics 2014, 1, 369-379.

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