Next Article in Journal
High Enzymatic Recovery and Purification of Xylooligosaccharides from Empty Fruit Bunch via Nanofiltration
Previous Article in Journal
Robust Design of PC/ABS Filled with Nano Carbon Black for Electromagnetic Shielding Effectiveness and Surface Resistivity
Previous Article in Special Issue
Dentistry 4.0 Concept in the Design and Manufacturing of Prosthetic Dental Restorations
Open AccessFeature PaperReview

A Comparison of Bioactive Glass Scaffolds Fabricated ‎by Robocasting from Powders Made by Sol–Gel and Melt-Quenching Methods

Department of Materials and Ceramic Engineering/CICECO—Aveiro Institute of Materials, University of Aveiro, 3810‎-‎193 Aveiro, Portugal
*
Authors to whom correspondence should be addressed.
Processes 2020, 8(5), 615; https://doi.org/10.3390/pr8050615
Received: 26 February 2020 / Revised: 11 May 2020 / Accepted: 16 May 2020 / Published: 21 May 2020
(This article belongs to the Special Issue Synthesis and Characterization of Biomedical Materials)
Bioactive glass scaffolds are used in bone and tissue biomedical implants, and there is great interest in their fabrication by additive manufacturing/3D printing techniques, such as robocasting. Scaffolds need to be macroporous with voids ≥100 m to allow cell growth and vascularization, biocompatible and bioactive, with mechanical properties matching the host tissue (cancellous bone for bone implants), and able to dissolve/resorb over time. Most bioactive glasses are based on silica to form the glass network, with calcium and phosphorous content for new bone growth, and a glass modifier such as sodium, the best known being 45S5 Bioglass®. 45S5 scaffolds were first robocast in 2013 from melt-quenched glass powder. Sol–gel-synthesized bioactive glasses have potential advantages over melt-produced glasses (e.g., greater porosity and bioactivity), but until recently were never robocast as scaffolds, due to inherent problems, until 2019 when high-silica-content sol–gel bioactive glasses (HSSGG) were robocast for the first time. In this review, we look at the sintering, porosity, bioactivity, biocompatibility, and mechanical properties of robocast sol–gel bioactive glass scaffolds and compare them to the reported results for robocast melt-quench-synthesized 45S5 Bioglass® scaffolds. The discussion includes formulation of the printing paste/ink and the effects of variations in scaffold morphology and inorganic additives/dopants. View Full-Text
Keywords: robocasting; bioactive glass; scaffold; sol–gel; 45S5 Bioglass®; biomaterials; biomedical implants robocasting; bioactive glass; scaffold; sol–gel; 45S5 Bioglass®; biomaterials; biomedical implants
Show Figures

Graphical abstract

MDPI and ACS Style

Ben-Arfa, B.A.E.; Pullar, R.C. A Comparison of Bioactive Glass Scaffolds Fabricated ‎by Robocasting from Powders Made by Sol–Gel and Melt-Quenching Methods. Processes 2020, 8, 615.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop