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Open AccessArticle

Green Synthesis of Potent Antimicrobial Silver Nanoparticles Using Different Plant Extracts and Their Mixtures

1
Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, P.O. Box 346, Ajman, UAE
2
Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, P.O. Box 346, Ajman, UAE
*
Author to whom correspondence should be addressed.
Processes 2019, 7(8), 510; https://doi.org/10.3390/pr7080510
Received: 21 June 2019 / Revised: 31 July 2019 / Accepted: 2 August 2019 / Published: 4 August 2019
(This article belongs to the Special Issue Green Separation and Extraction Processes)
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Abstract

Nano-sized metals have been introduced as a promising solution for microbial resistance to antimicrobial agents. Silver nanoparticles (AgNPs) have been proven to possess good antimicrobial activity. Green synthesis of AgNPs has been reported as safe, low cost and ecofriendly. This methodology uses extracts originating from different plants to reduce silver ions from AgNO3 into nano-sized particles. In this study, extracts of several plants including ginger, garlic, capsicum and their mixtures were successfully used to produce AgNPs. Numerous spectroscopic, light scattering and microscopic techniques were employed to characterize the synthesized AgNPs. Agar well diffusion assay was performed to investigate the antimicrobial activity of AgNPs. The biosynthesized AgNPs have spherical shape with a size range of 20–70 nm. Garlic extract, pure or in mixture with ginger extract, generated AgNPs of the smallest size. The presence of the plant-origin capping agents surrounding AgNPs was proven by Fourier-transform infrared spectroscopy. The AgNPs, at a concentration of 50 µg/mL, demonstrated potent antimicrobial activity against Staphyloccocus aureus, Escherichia coli and Candida albicans as indicated by the zones of inhibitions. Our results revealed that AgNPs having potent antimicrobial activity could be prepared using different pure plant extracts and their mixtures. View Full-Text
Keywords: AgNPs; green synthesis; plant extract; chemical methods; antibacterial; antifungal AgNPs; green synthesis; plant extract; chemical methods; antibacterial; antifungal
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Reda, M.; Ashames, A.; Edis, Z.; Bloukh, S.; Bhandare, R.; Abu Sara, H. Green Synthesis of Potent Antimicrobial Silver Nanoparticles Using Different Plant Extracts and Their Mixtures. Processes 2019, 7, 510.

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