sCD14 Level in Saliva of Children and Adolescents with and without Dental Caries, a Hurdle Model
Abstract
:1. Introduction
2. Materials and Methods
2.1. Inclusion and Exclusion Criteria
2.2. Study Protocol
2.3. Statistical Analysis
3. Results
3.1. Study Population
3.2. sCD14 Levels
3.3. CD14 and Caries
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Healthy N (%) | Decayed N (%) | X2 P | X2 P Trend | ||
---|---|---|---|---|---|
Gender | Male | 36 (46.2%) | 42 (53.8%) | 0.348 | 0.274 |
Female | 46 (54.8%) | 38 (45.2%) | |||
Age in tertiles | 6–9 years | 39 (42.9%) | 52 (57.7%) | 0.081 | 0.037 |
10–13 years | 30 (60.0%) | 20 (40.0%) | |||
14–16 years | 13 (61.9%) | 8 (38.1%) | |||
Oral Hygiene | Brushes 2 or more times daily | 66 (52.0%) | 61 (48.0%) | 0.642 | 0.512 |
Brushes less than twice daily | 16 (45.7%) | 19 (54.3%) | |||
CD14 μg/mL in quintiles | Less than 15.30 | 8 (24.2%) | 25 (75.8%) | 0.001 | 0.001 |
15.31–21.61 | 19 (59.4%) | 13 (40.6%) | |||
21.62–27.63 | 14 (43.8%) | 18 (56.2%) | |||
27.64–33.92 | 16 (50.0%) | 16 (50.0%) | |||
33.91–53.11 | 24 (75.0%) | 8 (25.0%) |
Healthy | Decayed | |
---|---|---|
Gender | ||
Girls | 27.1 ± 11.0 | 24.1 ± 10.1 |
Boys | 29.7 ± 10.7 | 20.1 ± 8.7 |
Age group (years) | ||
6–9 | 27.6 ± 9.4 | 22.9 ± 8.9 |
10–13 | 28.3 ± 12.7 | 22.5 ± 10.9 |
14–16 | 30.3 ± 11 | 18.7 ± 10.9 |
OR | 95% CI | Multivariate OR | 95% CI | |
---|---|---|---|---|
Oral_Hygiene: | ||||
Brushing once or less vs. more times a day | 1.285 | 0.607–2.748 | 1.286 | 0.575–2.917 |
sCD14> | ||||
2nd quintile vs. 1st | 0.219 | 0.072–0.616 | 0.172 | 0.049–0.541 |
3rd quintile vs. 1st | 0.411 | 0.138–1.165 | 0.305 | 0.088–0.968 |
4th quintile vs. 1st | 0.320 | 0.107–0.898 | 0.301 | 0.087–0.960 |
5th quintile vs. 1st | 0.107 | 0.032–0.315 | 0.086 | 0.023–0.278 |
sCD14 μg/mL | Probability Estimate | 95% CI |
---|---|---|
1 | 0.81 | 0.67–0.91 |
10 | 0.71 | 0.59–0.82 |
20 | 0.57 | 0.49–0.66 |
30 | 0.42 | 0.33–0.51 |
40 | 0.29 | 0.18–0.41 |
50 | 0.18 | 0.08–0.32 |
60 | 0.11 | 0.03–0.25 |
sCD 14 μg/mL | Number of Expected Caries | 95% CI |
---|---|---|
1 | 10.69 | 9.02–12.86 |
10 | 6.27 | 5.61–6.98 |
20 | 3.47 | 3.16–3.78 |
30 | 1.92 | 1.63–2.25 |
40 | 1.06 | 0.82–1.35 |
50 | 0.59 | 0.41–0.82 |
60 | 0.32 | 0.2–0.5 |
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Pellegrini, G.; Maddalone, M.; Malvezzi, M.; Toma, M.; Del Fabbro, M.; Canciani, E.; Dellavia, C. sCD14 Level in Saliva of Children and Adolescents with and without Dental Caries, a Hurdle Model. Children 2021, 8, 679. https://doi.org/10.3390/children8080679
Pellegrini G, Maddalone M, Malvezzi M, Toma M, Del Fabbro M, Canciani E, Dellavia C. sCD14 Level in Saliva of Children and Adolescents with and without Dental Caries, a Hurdle Model. Children. 2021; 8(8):679. https://doi.org/10.3390/children8080679
Chicago/Turabian StylePellegrini, Gaia, Marcello Maddalone, Matteo Malvezzi, Marilisa Toma, Massimo Del Fabbro, Elena Canciani, and Claudia Dellavia. 2021. "sCD14 Level in Saliva of Children and Adolescents with and without Dental Caries, a Hurdle Model" Children 8, no. 8: 679. https://doi.org/10.3390/children8080679