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Open AccessArticle

Neurological Complications and Associated Risk Factors in Children Affected with Chronic Kidney Disease

1
Pediatric Nephrology Center of Excellence, Faculty of Medicine, King Abdulaziz University, P.O.BOX 80215, Jeddah 21589, Saudi Arabia
2
Faculty of Medicine Department, King AbdulAziz University Hospital, P.O.BOX 80215, Jeddah 21589, Saudi Arabia
*
Author to whom correspondence should be addressed.
Children 2020, 7(6), 59; https://doi.org/10.3390/children7060059
Received: 31 March 2020 / Revised: 12 May 2020 / Accepted: 2 June 2020 / Published: 8 June 2020
To investigate the correlation between chronic kidney disease (CKD) and the development of neurological disease among pediatric patients in Saudi Arabia. The present retrospective study recruited patients admitted to King Abdulaziz University Hospital during 2018. We reviewed electronic records to collect data on essential demographics including age, gender, and nationality; history of prior CNS disease or related symptoms; results of neurological physical examination; and findings of radiological investigations such as abdominal ultrasound, dimercaptosuccinic acid scan, micturating cystourethrogram, diethylene triamine pentaacetic acid scan, brain computed tomography, and magnetic resonance imaging. The most commonly diagnosed renal pathologies were neurogenic bladder and cystic kidney disease. The most common neurological manifestation was seizure disorder. Males were more frequently affected with neurological sequelae than females. The prevalence of neurological disorders was higher in patients over two years old. The most frequently observed stage of chronic kidney disease was stage 5. Most children who were affected with a neurological disorder required hemodialysis as part of their management plan. Patients with chronic kidney disease are at a high risk of neurocognitive defects. The type of management and renal diagnosis are significant factors that should be considered when anticipating central nervous system involvement in the case of chronic kidney disease. View Full-Text
Keywords: chronic; kidney; disease; neurological; complications; children chronic; kidney; disease; neurological; complications; children
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Safdar, O.; Sindi, S.; Nazer, N.; Milyani, A.; Makki, A. Neurological Complications and Associated Risk Factors in Children Affected with Chronic Kidney Disease. Children 2020, 7, 59.

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