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Children 2019, 6(2), 24; https://doi.org/10.3390/children6020024

The Role of Probiotics in Preventing Allergic Disease

1
Department of Pediatrics, Section of Immunology, Allergy, Rheumatology, and Retrovirology, Texas Children’s Hospital, Houston, TX 77030, USA
2
Baylor College of Medicine, Department of Pediatrics, Section of Immunology, Allergy, Rheumatology, and Retrovirology, Houston, TX 77030, USA
*
Author to whom correspondence should be addressed.
Received: 20 November 2018 / Revised: 16 January 2019 / Accepted: 1 February 2019 / Published: 5 February 2019
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PDF [244 KB, uploaded 18 February 2019]

Abstract

The prevalence of allergic disorders has been increasing worldwide and significantly impacts the quality of life of the atopic individual. There has been an increased interest in the role of probiotics for the prevention and treatment of allergic disorders, given the recent evidence that atopy risk may be associated with a dysbiosis of the gut microbiome. Research in this area is ongoing with some studies showing possible benefits of probiotics, with seemingly little to no risk. While these studies suggest that there may be a promise in probiotic use for the prevention or treatment of allergy, further evidence is needed to determine its efficacy, optimal dosing, and strains needed for treatment. In this review, we discuss recently published studies examining the benefits, risks, and role of probiotics in preventing atopic dermatitis, asthma, allergic rhinitis, and food allergy. View Full-Text
Keywords: probiotics; microbiome; dysbiosis; atopy; food allergy; eczema; allergic rhinitis; asthma probiotics; microbiome; dysbiosis; atopy; food allergy; eczema; allergic rhinitis; asthma
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Wang, H.T.; Anvari, S.; Anagnostou, K. The Role of Probiotics in Preventing Allergic Disease. Children 2019, 6, 24.

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