Next Article in Journal
Structured Activity and Free Outdoor Play in Early Childhood Education and Care: An OSRAC-P Observational Study of Physical Activity Intensity and Context
Previous Article in Journal
Oral Health Conditions and Quality of Life Among Schoolchildren in Rural Tanzania: A Cross-Sectional Study
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Children
Volume 13
Issue 4
10.3390/children13040526
children-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Life-Threatening Gastrointestinal Bleeding in a Child with Acute Hepatitis A

by
Simona Zlatanova
1,2,*,
Meri Hristamyan
3 and
Kostadin Ketev
4,5
1
Department of Infectious Diseases, Parasitology and Tropical Medicine, Faculty of Medicine, Medical University of Plovdiv, Blvd Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria
2
Clinic of Infectious Diseases and Parasitology, St. George’s University Hospital, 4002 Plovdiv, Bulgaria
3
Department of Epidemiology and Disaster Medicine, Faculty of Public Health, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria
4
Department of Pediatrics, St. George’s University Hospital, 4002 Plovdiv, Bulgaria
5
Medical Simulation Training Center, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria
*
Author to whom correspondence should be addressed.
Children 2026, 13(4), 526; https://doi.org/10.3390/children13040526
Submission received: 2 February 2026 / Revised: 25 March 2026 / Accepted: 8 April 2026 / Published: 10 April 2026
(This article belongs to the Section Pediatric Infectious Diseases)
Versions Notes

Abstract

Background: Hepatitis A virus (HAV) infection is a common cause of acute viral hepatitis in children. Severe complications are rare but may occur, particularly in older children or in the presence of concomitant conditions. Case Presentation: We report the case of an 11-year-old girl with acute hepatitis A with severe hepatic derangements who developed life-threatening upper gastrointestinal bleeding due to a previously undiagnosed duodenal ulcer. Emergency endoscopy confirmed active bleeding from a duodenal ulcer, and the patient survived the complications with treatment with a proton pump inhibitor and hemostatic management with blood products. Conclusions: Although hepatitis A is generally benign in children, this case highlights the potential for severe and life-threatening complications.
Keywords: hepatitis A; pediatrics; gastrointestinal bleeding; duodenal ulcer; hyperbilirubinemia; coagulopathy hepatitis A; pediatrics; gastrointestinal bleeding; duodenal ulcer; hyperbilirubinemia; coagulopathy

Share and Cite

MDPI and ACS Style

Zlatanova, S.; Hristamyan, M.; Ketev, K. Life-Threatening Gastrointestinal Bleeding in a Child with Acute Hepatitis A. Children 2026, 13, 526. https://doi.org/10.3390/children13040526

AMA Style

Zlatanova S, Hristamyan M, Ketev K. Life-Threatening Gastrointestinal Bleeding in a Child with Acute Hepatitis A. Children. 2026; 13(4):526. https://doi.org/10.3390/children13040526

Chicago/Turabian Style

Zlatanova, Simona, Meri Hristamyan, and Kostadin Ketev. 2026. "Life-Threatening Gastrointestinal Bleeding in a Child with Acute Hepatitis A" Children 13, no. 4: 526. https://doi.org/10.3390/children13040526

APA Style

Zlatanova, S., Hristamyan, M., & Ketev, K. (2026). Life-Threatening Gastrointestinal Bleeding in a Child with Acute Hepatitis A. Children, 13(4), 526. https://doi.org/10.3390/children13040526

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop