Effectiveness of Bundled Interventions for the Prevention of Neonatal Hypothermia in Low-Income Settings: A Quality Improvement Project in a Referral Hospital in Ethiopia
Abstract
:1. Introduction
2. Aim
3. Materials and Methods
3.1. Study Design
3.2. Setting
3.3. Patients
3.4. Intervention
3.5. Outcome Measures
3.6. Data Collection
3.7. Statistical Analysis
4. Results
5. Discussion
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
List of Abbreviations
HICs | High-income countries |
NSCU | Neonatal Special Care Unit |
WHO | World Health Organization |
QI | Quality improvement |
NICU | Neonatal Intensive Care Unit |
KMC room | Kangaroo Mother Care room |
PDSA cycle | Plan–Do–Study–Act cycle |
References
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Area of Intervention | Action |
---|---|
Training activity | - Hypothermia prevention for delivery room staff. - Hypothermia prevention for NSCU staff. - Hypothermia prevention for students attending the ward. - KMC for mothers hosted in Kangaroo room. |
Delivery room | The following procedures were implemented after the training course: - Placing a door at the newborn perinatal assistance room and turning on an electric radiator at least 1 h before delivery. - Radiant warmer on for at least half an hour before delivery with 100% heater output. - Prewarmed towel. - Removal of wet linen and wrapping in a prewarmed towel. - Skin-to-skin contact in the first hour after birth for stable newborns. - Appropriate newborn clothing (warm clothes including cap, socks, mittens, and sweater). - Newborn wrapping with prewarmed cotton and swaddle covering with wool blanket before moving to NSCU. |
NSCU | The following procedures were implemented after the training course: - Turn on the electric radiator if room temperature < 26 °C. - Keep doors and windows closed. - Cover all newborns with cap, socks, and also mittens in case of birth weight < 1500 g. - Encourage Kangaroo care in NSCU also for unstable babies. - Cover with a blanket all the babies that are not under the radiant warmer. - Check body temperature every 30–60 min until 36.5 °C after a hypothermia episode. Always write the body temperature on the vital signs charts and alert the next shift. - Change the diaper at least 3 times a day. - Put two electric warmers near the cradle during phototherapy. - Let the radiant warmer always be on and set the power % to ensure a body temperature between 36.5 and 37.5 °C. |
Kangaroo Mother Care (KMC) room | - Ensure KMC for all babies under 2000 g. - Ensure all newborns in KMC wear a hat and are covered with a blanket. - After managing hypothermia, check body temperature every 30–60 min until it reaches 36.5 °C. Always write the body temperature on the vital signs charts and alert the next shift. - Change the diaper at least 3 times a day. |
Pre-Intervention Period (n = 117) | Post-Intervention Period (n = 87) | p-Value | |
---|---|---|---|
Mode of delivery: | 0.36 | ||
Spontaneous vaginal delivery | 63 (54%) | 52 (60%) | |
Assisted vaginal delivery | 6 (5%) | 7 (8%) | |
Cesarean section | 48 (41%) | 28 (32%) | |
Males | 73 (62%) | 46 (53%) | 0.22 |
Birth weight: | 0.43 | ||
≥2500 g | 75 (64%) | 62 (71%) | |
1500–2499 g | 35 (30%) | 19 (22%) | |
≤1499 g | 7 (6%) | 6 (7%) | |
Respiratory distress | 66 (56%) | 50 (57%) | 0.99 |
Jaundice | 13 (11%) | 4 (5%) | 0.13 |
Early onset infections | 26 (22%) | 23 (26%) | 0.59 |
Perinatal asphyxia | 8 (7%) | 8 (9%) | 0.72 |
Oxygen therapy | 81 (69%) | 62 (71%) | 0.87 |
Oxygen therapy (hours) | 16 (7–43) | 12 (8–34) | 0.50 |
Pre-Intervention Period (n = 117) | Post-Intervention Period (n = 87) | p-Value | |
---|---|---|---|
Neonatal temperature at admission, °C | 35.6 (35.1–36.2) | 36.0 (35.4–36.6) | 0.004 |
Hypothermia (<36.5 °C) at admission | 94 (80%) | 61 (70%) | 0.13 |
Average temperature during hospitalization, °C | 36.3 (36.0–36.4) | 36.7 (35.6–36.8) | <0.0001 |
Number of mild hypothermia (36–36.4 °C) episodes per day during hospitalization | 1.0 (0.5–1.3) | 0.5 (0.0–1.0) | <0.0001 |
Number of moderate hypothermia (32–35.9 °C) episodes per day during hospitalization | 0.7 (0.3–1.0) | 0.2 (0.0–0.5) | <0.0001 |
Number of severe hypothermia (<32 °C) episodes per day during hospitalization | Nil | Nil | - |
Number of temperature checks per day during hospitalization | 3.0 (2.5–3.2) | 3.0 (2.7–3.3) | 0.17 |
Mortality | 5 (4%) | 6 (7%) | 0.61 |
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© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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Baracetti, M.; Hagos, E.; Tolera, J.; Cavallin, F.; Facci, E.; Putoto, G.; Manenti, F.; Trevisanuto, D.; Pietravalle, A. Effectiveness of Bundled Interventions for the Prevention of Neonatal Hypothermia in Low-Income Settings: A Quality Improvement Project in a Referral Hospital in Ethiopia. Children 2025, 12, 709. https://doi.org/10.3390/children12060709
Baracetti M, Hagos E, Tolera J, Cavallin F, Facci E, Putoto G, Manenti F, Trevisanuto D, Pietravalle A. Effectiveness of Bundled Interventions for the Prevention of Neonatal Hypothermia in Low-Income Settings: A Quality Improvement Project in a Referral Hospital in Ethiopia. Children. 2025; 12(6):709. https://doi.org/10.3390/children12060709
Chicago/Turabian StyleBaracetti, Margherita, Eleni Hagos, Jiksa Tolera, Francesco Cavallin, Enzo Facci, Giovanni Putoto, Fabio Manenti, Daniele Trevisanuto, and Andrea Pietravalle. 2025. "Effectiveness of Bundled Interventions for the Prevention of Neonatal Hypothermia in Low-Income Settings: A Quality Improvement Project in a Referral Hospital in Ethiopia" Children 12, no. 6: 709. https://doi.org/10.3390/children12060709
APA StyleBaracetti, M., Hagos, E., Tolera, J., Cavallin, F., Facci, E., Putoto, G., Manenti, F., Trevisanuto, D., & Pietravalle, A. (2025). Effectiveness of Bundled Interventions for the Prevention of Neonatal Hypothermia in Low-Income Settings: A Quality Improvement Project in a Referral Hospital in Ethiopia. Children, 12(6), 709. https://doi.org/10.3390/children12060709