Efficacy of Laser Pulpotomy vs. Conventional Vital Pulpotomy in Primary Teeth: A Comparative Clinical Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Inclusion Criteria
- Clinical criteria: Absence of spontaneous pain, absence of swelling, no tenderness on percussion, no pathological mobility, absence of sinus tract, and no initially unsuccessful hemorrhage control.
- Radiographic criteria: Teeth with no radiographic signs of inter-radicular bone loss, no loss of lamina dura and periodontal ligament widening, and no physiological root resorption of more than one-third of the root.
- First subgroup (10 teeth)—Ca(OH)2 applied as a pulpotomy agent;
- Second subgroup (10 teeth)—MTA applied as a pulpotomy agent.
- First subgroup (10 teeth)—Ca(OH)2 applied as a pulpotomy agent;
- Second subgroup (10 teeth)—MTA applied as a pulpotomy agent.
2.2. Clinical Procedure
2.2.1. Conventional Pulpotomy
2.2.2. Laser Pulpotomy
2.3. Therapeutic Outcomes
2.4. Statistical Analysis
3. Results
3.1. Clinical Outcomes
3.2. Radiological Outcomes
3.3. Comparison of Different Methods
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Skeie, M.S.; Sen, A.; Dahllöf, G.; Fagerhaug, T.N.; Høvik, H.; Klock, K.S. Dental Caries at Enamel and Dentine Level among European Adolescents—A Systematic Review and Meta-Analysis. BMC Oral Health 2022, 22, 620. [Google Scholar] [CrossRef]
- Ritwik, P. A Review of Pulp Therapy for Primary and Immature Permanent Teeth. J. Calif. Dent. Assoc. 2013, 41, 585–595. [Google Scholar] [CrossRef] [PubMed]
- Igna, A. Vital Pulp Therapy in Primary Dentition: Pulpotomy—A 100-Year Challenge. Children 2021, 8, 841. [Google Scholar] [CrossRef]
- Wang, S.; Peng, C.F.; Liu, H. Pulpotomy of Human Primary Molars with Novel Bioceramic Material. Beijing Da Xue Xue Bao Yi Xue Ban = J. Peking Univ. Health Sci. 2022, 54, 1196–1201. [Google Scholar] [CrossRef]
- Tewari, N.; Goel, S.; Mathur, V.P.; O’Connell, A.C.; Johnson, R.M.; Rahul, M.; Sultan, F.; Goswami, M.; Srivastav, S.; Ritwik, P. Success of Medicaments and Techniques for Pulpotomy of Primary Teeth: An Overview of Systematic Reviews. Int. J. Paediatr. Dent. 2022, 32, 828–842. [Google Scholar] [CrossRef] [PubMed]
- Nowak, A.J.; Christensen, J.R.; Mabry, T.R.; Townsend, J.A.; Wells, M.H. Pediatric Dentistry Infancy Through Adolescence, 6th ed.; Elsevier Saunders: St. Louis, MO, USA, 2018. [Google Scholar]
- American Academy of Pediatric Dentistry. Pulp Therapy for Primary and Immature Permanent Teeth. In The Reference Manual of Pediatric Dentistry; American Academy of Pediatric Dentistry: Chicago, IL, USA, 2024. [Google Scholar]
- Durmus, B.; Tanboga, I. In Vivo Evaluation of the Treatment Outcome of Pulpotomy in Primary Molars Using Diode Laser, Formocresol, and Ferric Sulphate. Photomed. Laser Surg. 2014, 32, 289–295. [Google Scholar] [CrossRef] [PubMed]
- Al-Dlaigan, Y.H. Pulpotomy Medicaments Used in Deciduous Dentition: An Update. J. Contemp. Dent. Pract. 2015, 16, 486–503. [Google Scholar] [CrossRef]
- Torabinejad, M.; Hong, C.; Lee, S.; Monsef, M.; Pittford, T. Investigation of Mineral Trioxide Aggregate for Root-End Filling in Dogs. J. Endod. 1995, 21, 603–608. [Google Scholar] [CrossRef]
- Holan, G.; Eidelman, E.; Fuks, A.B. Long-Term Evaluation of Pulpotomy in Primary Molars Using Mineral Trioxide Aggregate or Formocresol. Pediatr. Dent. 2005, 27, 129–136. [Google Scholar]
- Eidelman, E.; Holan, G.; Fuks, A.B. Mineral Trioxide Aggregate vs. Formocresol in Pulpotomized Primary Molars: A Preliminary Report. Pediatr. Dent. 2001, 23, 15–18. [Google Scholar]
- Vilella-Pastor, S.; Sáez, S.; Veloso, A.; Guinot-Jimeno, F.; Mercadé, M. Long-Term Evaluation of Primary Teeth Molar Pulpotomies with Biodentine and MTA: A CONSORT Randomized Clinical Trial. Eur. Arch. Paediatr. Dent. 2021, 22, 685–692. [Google Scholar] [CrossRef] [PubMed]
- Galui, S.; Pal, S.; Mahata, S.; Saha, S.; Sarkar, S. Laser and Its Use in Pediatric Dentistry: A Review of Literature and a Recent Update. Int. J. Pedod. Rehabil. 2019, 4, 1. [Google Scholar] [CrossRef]
- Gupta, G. Laser Pulpotomy—An Effective Alternative to Conventional Techniques: A 12 Months Clinicoradiographic Study. Int. J. Clin. Pediatr. Dent. 2015, 8, 18–21. [Google Scholar] [CrossRef] [PubMed]
- Afkhami, F.; Rostami, G.; Xu, C.; Walsh, L.J.; Peters, O.A. The Application of Lasers in Vital Pulp Therapy: A Review of Histological Effects. Lasers Med. Sci. 2023, 38, 215. [Google Scholar] [CrossRef] [PubMed]
- Theodoro, L.H.; Marcantonio, R.A.C.; Wainwright, M.; Garcia, V.G. LASER in Periodontal Treatment: Is It an Effective Treatment or Science Fiction? Braz. Oral Res. 2021, 35, e099. [Google Scholar] [CrossRef]
- Tetè, G.; Ferrante, L.; Moretto, M.; Rellandini, G.; Polizzi, E. The Efficacy of the Diode Laser at 800-980 Nm as an Aid to Non-Surgical Therapy in Periodontitis Treatment: A Review of Literature. J. Biol. Regul. Homeost. Agents 2021, 35, 51–63. [Google Scholar] [CrossRef]
- Carosi, P.; Barlattani, A.; Lorenzi, C.; Dolci, A.; Bianchi, N.; Arcuri, C. Diode Laser as an Adjunct to Nonsurgical Chronic Periodontitis Therapy: A Review. J. Biol. Regul. Homeost. Agents 2020, 34, 45–54. [Google Scholar]
- Fornaini, C.; Fekrazad, R.; Rocca, J.-P.; Zhang, S.; Merigo, E. Use of Blue and Blue-Violet Lasers in Dentistry: A Narrative Review. J. Lasers Med. Sci. 2021, 12, e31. [Google Scholar] [CrossRef]
- Fuks, A.B.; Papagiannoulis, L.; Duggal, M.S. Pulpotomy in Primary Teeth: Review of the Literature According to Standardized Assessment Criteria. Eur. Arch. Paediatr. Dent. 2006, 1, 64–72. [Google Scholar] [CrossRef]
- Golpayegani, M.V.; Ansari, G.; Tadayon, N.; Shams, S.; Mir, M. Low-Level Laser Therapy for Pulpotomy Treatment of Primary Molars. Front. Dent. 2009, 6, 168–174. [Google Scholar]
- Ibricevic, H.; Al-Jame, Q. Ferric Sulfate as Pulpotomy Agent in Primary Teeth: Twenty Month Clinical Follow-Up. J. Clin. Pediatr. Dent. 2000, 24, 269–272. [Google Scholar] [CrossRef] [PubMed]
- Kaya, C.; Elbay, Ü.Ş.; Elbay, M.; Uçar, G. The Comparison of Calcium Hydroxide + Biostimulation, Calcium Hydroxide, Formocresol, and MTA Pulpotomies without Biostimulation in Primary Teeth: 12-Months Clinical and Radiographic Follow-Up. Lasers Med. Sci. 2022, 37, 2545–2554. [Google Scholar] [CrossRef] [PubMed]
- Smaïl-Faugeron, V.; Glenny, A.-M.; Courson, F.; Durieux, P.; Muller-Bolla, M.; Fron Chabouis, H. Pulp Treatment for Extensive Decay in Primary Teeth. Cochrane Database Syst. Rev. 2018, 5, CD003220. [Google Scholar] [CrossRef]
- Yadav, P.; Indushekar, K.; Saraf, B.; Sheoran, N.; Sardana, D. Comparative Evaluation of Ferric Sulfate, Electrosurgical and Diode Laser on Human Primary Molars Pulpotomy: An “in-Vivo” Study. Laser Ther. 2014, 23, 41–47. [Google Scholar] [CrossRef] [PubMed]
- Huth, K.C.; Paschos, E.; Hajek-Al-Khatar, N.; Hollweck, R.; Crispin, A.; Hickel, R.; Folwaczny, M. Effectiveness of 4 Pulpotomy Techniques—Randomized Controlled Trial. J. Dent. Res. 2005, 84, 1144–1148. [Google Scholar] [CrossRef]
- Kabaktchieva, R.; Gateva, N. Vital Pulpotomy in Primary Teeth with Mineral Trioxide Aggregate (MTA). J. IMAB—Annu. Proceeding (Sci. Pap.) 2010, 15, 102–108. [Google Scholar] [CrossRef]
- Al-Hezaimi, K.; Al-Shalan, T.A.; Naghshbandi, J.; Oglesby, S.; Simon, J.H.S.; Rotstein, I. Antibacterial Effect of Two Mineral Trioxide Aggregate (MTA) Preparations Against Enterococcus Faecalis and Streptococcus Sanguis In Vitro. J. Endod. 2006, 32, 1053–1056. [Google Scholar] [CrossRef]
- Ji, M.; Chi, Y.; Wang, Y.; Xiong, K.; Chen, X.; Zou, L. An in Vitro Evaluation of Antimicrobial Activity of a Fast-Setting Endodontic Material. Sci. Rep. 2022, 12, 16021. [Google Scholar] [CrossRef]
- Morita, M.; Kitagawa, H.; Nakayama, K.; Kitagawa, R.; Yamaguchi, S. Imazato Satoshi Antibacterial Activities and Mineral Induction Abilities of Proprietary MTA Cements. Dent. Mater. J. 2021, 40, 297–303. [Google Scholar] [CrossRef]
- ElSebaai, A.; Wahba, A.H.; Grawish, M.E.; Elkalla, I.H. Calcium Hydroxide Paste, Mineral Trioxide Aggregate, and Formocresol as Direct Pulp Capping Agents in Primary Molars: A Randomized Controlled Clinical Trial. Pediatr. Dent. 2022, 44, 411–417. [Google Scholar]
- Stratigaki, E.; Tong, H.J.; Seremidi, K.; Kloukos, D.; Duggal, M.; Gizani, S. Contemporary Management of Deep Caries in Primary Teeth: A Systematic Review and Meta-Analysis. Eur. Arch. Paediatr. Dent. 2022, 23, 695–725. [Google Scholar] [CrossRef] [PubMed]
- Uloopi, K.S. Clinical Evaluation of Low Level Diode Laser Application For Primary Teeth Pulpotomy. J. Clin. Diagn. Res. 2016, 10, 67–70. [Google Scholar] [CrossRef]
- Kalaskar, R.; Kalaskar, A.; Gala, U.P.; Honaje, N.V.; Doiphode, A.R. Clinical and Radiographic Efficacy of Low-Level Laser Therapy and Formocresol as Pulpotomy Agents in Primary Molars: A Systematic Review and Meta-Analysis. Int. J. Clin. Pediatr. Dent. 2024, 17, 1075–1085. [Google Scholar] [CrossRef]
- Li, W.; Yang, B.; Shi, J. Efficacy of Pulpotomy for Permanent Teeth with Carious Pulp Exposure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. PLoS ONE 2024, 19, e0305218. [Google Scholar] [CrossRef]
- Chandran, V.; Venkitachalam, R.; Menon, M.; Varma, B.; Sanjeevan, V. Effect of LASER Therapy Vs Conventional Techniques on Clinical and Radiographic Outcomes of Deciduous Molar Pulpotomy: A Systematic Review and Meta-Analysis. J. Clin. Exp. Dent. 2020, 12, 588–596. [Google Scholar] [CrossRef] [PubMed]
- Sun, G.; Tunér, J. Low-Level Laser Therapy in Dentistry. Dent. Clin. N. Am. 2004, 48, 1061–1076. [Google Scholar] [CrossRef] [PubMed]
- Jamali, S.; Nasrabadi, N.; Darvish, M.; Khosravi, S. Clinical and Radiographic Outcomes Comparison between Various Types of Laser Pulpotomy and Formocresol Pulpotomy on Primary Molars: A Systematic Review and Meta-Analysis. J. Oral Maxillofac. Surg. Med. Pathol. 2021, 33, 75–82. [Google Scholar] [CrossRef]
- Ansari, G.; Safi Aghdam, H.; Taheri, P.; Ghazizadeh Ahsaie, M. Laser Pulpotomy—An Effective Alternative to Conventional Techniques—A Systematic Review of Literature and Meta-Analysis. Lasers Med. Sci. 2018, 33, 1621–1629. [Google Scholar] [CrossRef]
- Niranjani, K. Clinical Evaluation of Success of Primary Teeth Pulpotomy Using Mineral Trioxide Aggregate®, Laser and BiodentineTM—An In Vivo Study. J. Clin. Diagn. Res. 2015, 9, 35–37. [Google Scholar] [CrossRef]
Clinical Parameter | Conventional Pulpotomy | Laser Pulpotomy | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Months | I | III | VI | I | III | VI | |||||||
Presence/Absence | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | |
Pain | Ca(OH)2 | 0.0 | 100.0 | 0.0 | 90.0 | 10.0 | 90.0 | 10.0 | 90.0 | 10.0 | 90.0 | 0.0 | 90.0 |
MTA | 20.0 | 80.0 | 0.0 | 100.0 | 0.0 | 100.0 | 0.0 | 90.0 | 0.0 | 90.0 | 10.0 | 80.0 | |
Sinus Tract | Ca(OH)2 | 0.0 | 100.0 | 0.0 | 90.0 | 0.0 | 100.0 | 0.0 | 100.0 | 0.0 | 100.0 | 0.0 | 90.0 |
MTA | 0.0 | 80.0 | 0.0 | 80.0 | 0.0 | 100.0 | 0.0 | 90.0 | 0.0 | 80.0 | 0.0 | 90.0 | |
Swelling | Ca(OH)2 | 0.0 | 100.0 | 10.0 | 80.0 | 0.0 | 100.0 | 0.0 | 100.0 | 0.0 | 100.0 | 10.0 | 80.0 |
MTA | 0.0 | 80.0 | 0.0 | 80.0 | 0.0 | 100.0 | 0.0 | 90.0 | 0.0 | 80.0 | 0.0 | 90.0 | |
Mobility | Ca(OH)2 | 0.0 | 100.0 | 00. | 90.0 | 10.0 | 90.0 | 0.0 | 100.0 | 10.0 | 90.0 | 0.0 | 90.0 |
MTA | 0.0 | 80.0 | 0.0 | 80.0 | 0.0 | 100.0 | 0.0 | 90.0 | 0.0 | 80.0 | 0.0 | 90.0 | |
Premature Exfoliation | Ca(OH)2 | 0.0 | 100.0 | 0.0 | 90.0 | 10.0 | 90.0 | 0.0 | 100.0 | 10.0 | 90.0 | 0.0 | 90.0 |
MTA | 0.0 | 80.0 | 0.0 | 80.0 | 0.0 | 100.0 | 0.0 | 90.0 | 0.0 | 80.0 | 0.0 | 90.0 |
Radiological Parameter | Conventional Pulpotomy | Laser Pulpotomy | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Months | I | III | VI | I | III | VI | |||||||
Presence/Absence | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | Pr [%] | Ab [%] | |
Periodontal Ligament Widening | Ca(OH)2 | 0.0 | 100.0 | 0.0 | 90.0 | 10.0 | 90.0 | 0.0 | 100.0 | 10.0 | 90.0 | 10.0 | 80.0 |
MTA | 0.0 | 80.0 | 20.0 | 60.0 | 20.0 | 80.0 | 0.0 | 90.0 | 0.0 | 80.0 | 0.0 | 90.0 | |
Internal/External Resorption | Ca(OH)2 | 0.0 | 100.0 | 10.0 | 80.0 | 20.0 | 80.0 | 0.0 | 100.0 | 20.0 | 80.0 | 10.0 | 80.0 |
MTA | 0.0 | 80.0 | 20.0 | 60.0 | 20.0 | 80.0 | 0.0 | 90.0 | 0.0 | 80.0 | 10.0 | 80.0 | |
Furcal/Periapical Radiolucency | Ca(OH)2 | 0.0 | 100.0 | 10.0 | 80.0 | 10.0 | 90.0 | 0.0 | 100.0 | 10.0 | 90.0 | 0.0 | 90.0 |
MTA | 0.0 | 80.0 | 0.0 | 80.0 | 20.0 | 80.0 | 0.0 | 90.0 | 0.0 | 80.0 | 0.0 | 90.0 |
Conventional Method/Ca (OH)2 | Conventional Method/MTA | Fisher Exact Test p-Values | |||
---|---|---|---|---|---|
Follow-Up [Months] | Success [%] | Failure [%] | Success [%] | Failure [%] | |
I | 100 | 0 | 60 | 20 | 0.1830 |
III | 70 | 20 | 60 | 20 | 0.6647 |
VI | 70 | 30 | 80 | 20 | 0.5000 |
Laser/Ca (OH)2 | Laser /MTA | ||||
Success [%] | Failure [%] | Success [%] | Failure [%] | ||
I | 90 | 10 | 100 | 0 | 0.5263 |
III | 80 | 20 | 100 | 0 | 0.2632 |
VI | 70 | 30 | 77.8 | 22.2 | 0.5557 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Simonoska, J.; Bjelica, R.; Dimkov, A.; Simjanovska, J.; Gabrić, D.; Gjorgievska, E. Efficacy of Laser Pulpotomy vs. Conventional Vital Pulpotomy in Primary Teeth: A Comparative Clinical Analysis. Children 2025, 12, 341. https://doi.org/10.3390/children12030341
Simonoska J, Bjelica R, Dimkov A, Simjanovska J, Gabrić D, Gjorgievska E. Efficacy of Laser Pulpotomy vs. Conventional Vital Pulpotomy in Primary Teeth: A Comparative Clinical Analysis. Children. 2025; 12(3):341. https://doi.org/10.3390/children12030341
Chicago/Turabian StyleSimonoska, Jasna, Roko Bjelica, Aleksandar Dimkov, Jasmina Simjanovska, Dragana Gabrić, and Elizabeta Gjorgievska. 2025. "Efficacy of Laser Pulpotomy vs. Conventional Vital Pulpotomy in Primary Teeth: A Comparative Clinical Analysis" Children 12, no. 3: 341. https://doi.org/10.3390/children12030341
APA StyleSimonoska, J., Bjelica, R., Dimkov, A., Simjanovska, J., Gabrić, D., & Gjorgievska, E. (2025). Efficacy of Laser Pulpotomy vs. Conventional Vital Pulpotomy in Primary Teeth: A Comparative Clinical Analysis. Children, 12(3), 341. https://doi.org/10.3390/children12030341