The Need for New Biomarkers to Assist with Stroke Prevention and Prediction of Post-Stroke Therapy Based on Plasma-Derived Extracellular Vesicles
Abstract
:1. Introduction
1.1. The Molecular and Cellular Responses of the Aged Brain to Focal Ischemia
1.2. Neurovascular Unit Remodeling in Response to Cerebral Ischemia
1.2.1. Astroglia Responses to Cerebral Ischemia
Astrocytic Responses to Cerebral Ischemia in Aged Subjects
Microglia Responses to Cerebral Ischemia in Aged Subjects
1.3. Current Recanalization Therapies and Rehabilitation Options
1.4. Neuronal Replacement Strategies
1.5. Prevention Could Be More Successful than Investing in Stroke Therapies
1.6. Neurovascular Unit-Derived Exosomes in Response to Stroke
1.7. Brain EVs as Plasma Biomarkers of Cerebral Ischemia
2. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Driga, M.P.; Catalin, B.; Olaru, D.G.; Slowik, A.; Plesnila, N.; Hermann, D.M.; Popa-Wagner, A. The Need for New Biomarkers to Assist with Stroke Prevention and Prediction of Post-Stroke Therapy Based on Plasma-Derived Extracellular Vesicles. Biomedicines 2021, 9, 1226. https://doi.org/10.3390/biomedicines9091226
Driga MP, Catalin B, Olaru DG, Slowik A, Plesnila N, Hermann DM, Popa-Wagner A. The Need for New Biomarkers to Assist with Stroke Prevention and Prediction of Post-Stroke Therapy Based on Plasma-Derived Extracellular Vesicles. Biomedicines. 2021; 9(9):1226. https://doi.org/10.3390/biomedicines9091226
Chicago/Turabian StyleDriga, Mircea Popescu, Bogdan Catalin, Denisa Greta Olaru, Agnieszka Slowik, Nikolaus Plesnila, Dirk M. Hermann, and Aurel Popa-Wagner. 2021. "The Need for New Biomarkers to Assist with Stroke Prevention and Prediction of Post-Stroke Therapy Based on Plasma-Derived Extracellular Vesicles" Biomedicines 9, no. 9: 1226. https://doi.org/10.3390/biomedicines9091226