Vasculitis: From Target Molecules to Novel Therapeutic Approaches

Round 1

Reviewer 1 Report

Small and large vessels vasculitis is often underestimated. Classification and pathogenesis of different types of vasculitis are useful and  very well described together with a comprehensive description of the therapeutic targets with different drugs

Author Response

Thanks for your good comments. 

Reviewer 2 Report

Dear Author,

The review entitled Vasculitis: From Targer Molecules to Novel Therapeutic Approaches is a comprehensive review, which provides valuable information about the inflammation of vessels and the possibility of treatment. I have following minor comments:

• In Table 1 the „K“ is missing in Kawasaki disease
• Section 3.6.1. – the number of citations and the punctuation at the end of the sentence should be corrected.
• Are there any information about the IFN-Gamma in vasculitis treatment?
• In section 3.1.3. – TNF involvement in vasculitits, should be clearly stated whether it is only TNF alpha.

Author Response

2021.06.17

Editor-in-Chief

Biomedicines

Manuscript ID: biomedicines-1227583

Manuscript Title: Vasculitis: From Target Molecules to Novel Therapeutic Approaches

Thanks to carefully review the manuscript of the author.

[Reviewer ]

1. In Table 1 the „K“ is missing in Kawasaki disease

- As you commented, I added the missing letter ”K” in table 1.

2. Section 3.6.1. – the number of citations and the punctuation at the end of the sentence should be corrected.

- As you commented, I corrected the position of the period.

3. Are there any information about the IFN-Gamma in vasculitis treatment?

- Thanks for your good comment, however, there seems to be no evidence for interferon gamma therapy in vasculitis.

4. In section 3.1.3. – TNF involvement in vasculitits, should be clearly stated whether it is only TNF alpha.

- As you recommended, I revised TNF to TNF- α.