Chronic Glaucoma Using Biodegradable Microspheres to Induce Intraocular Pressure Elevation. Six-Month Follow-Up
Round 1
Reviewer 1 Report
Comments are provided in the attached file.
Comments for author File: Comments.pdf
Author Response
See attached file
Author Response File: Author Response.pdf
Reviewer 2 Report
The authors compared two rat models for glaucoma. This study is well designed and conducted. I only have a few comments:
- Bonferroni correction is probably too harsh as the those comparisons are not totally random. False discovery rate correction probably can give better results.
- Maybe the authors can further perform survival analyses with some thresholds to define glaucoma or ocular hypertension.
- If the authors could further test and compare the rat's response to light stimuli between the two models, the models will be more convincing.
- Three decimal digits precision is unnecessary. In most cases, you only need two decimal digits.
Author Response
See attached file
Author Response File: Author Response.pdf
Round 2
Reviewer 1 Report
The authors have addressed all the review questions