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Biomedicines 2018, 6(1), 30; https://doi.org/10.3390/biomedicines6010030

The Repertoire of Adenovirus in Human Disease: The Innocuous to the Deadly

Department of Medicine, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
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Received: 27 January 2018 / Revised: 26 February 2018 / Accepted: 1 March 2018 / Published: 7 March 2018
(This article belongs to the Special Issue Adenoviruses: From Virus to Medicine)
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Abstract

Adenoviridae is a family of double-stranded DNA viruses that are a significant cause of upper respiratory tract infections in children and adults. Less commonly, the adenovirus family can cause a variety of gastrointestinal, ophthalmologic, genitourinary, and neurologic diseases. Most adenovirus infections are self-limited in the immunocompetent host and are treated with supportive measures. Fatal infections can occur in immunocompromised patients and less frequently in the healthy. Adenoviral vectors are being studied for novel biomedical applications including gene therapy and immunization. In this review we will focus on the spectrum of adenoviral infections in humans. View Full-Text
Keywords: adenovirus; biology; immunocompetent; immunocompromised adenovirus; biology; immunocompetent; immunocompromised
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Khanal, S.; Ghimire, P.; Dhamoon, A.S. The Repertoire of Adenovirus in Human Disease: The Innocuous to the Deadly. Biomedicines 2018, 6, 30.

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