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Article

Silver Nanoparticles Grown on Cross-Linked Poly (Methacrylic Acid) Microspheres: Synthesis, Characterization, and Antifungal Activity Evaluation

1
Research Unit of Advanced, Composite, Nano-Materials and Nanotechnology, School of Chemical Engineering, National Technical University of Athens, 9 Heroon Polytechniou St., Zographos, GR-15773 Athens, Greece
2
Section of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, GR-15771 Athens, Greece
*
Author to whom correspondence should be addressed.
Academic Editor: Maria Grzeszczuk
Chemosensors 2021, 9(7), 152; https://doi.org/10.3390/chemosensors9070152
Received: 13 May 2021 / Revised: 18 June 2021 / Accepted: 19 June 2021 / Published: 23 June 2021
(This article belongs to the Special Issue Nanotechnology for Sensing, Medical and Environmental Application)
Silver nanoparticles (AgNPs) exert profound physicochemical, biological, and antimicrobial properties, therefore, they have been extensively studied for a variety of applications such as food packaging and cultural heritage protection. However, restrictions in their stability, aggregation phenomena, and toxicity limit their extensive use. Hence, the use of functional substrates that promote the silver nanoparticles’ growth and allow the formation of uniform-sized, evenly distributed, as well as stable nanoparticles, has been suggested. This study reports on the fabrication and the characterization of hydrophilic polymer spheres including nanoparticles with intrinsic antifungal properties. Poly (methacrylic acid) microspheres were synthesized, employing the distillation precipitation method, to provide monodisperse spherical substrates for the growth of silver nanoparticles, utilizing the co-precipitation of silver nitrate in aqueous media. The growth and the aggregation potential of the silver nanoparticles were studied, whereas the antifungal activity of the produced nanostructures was evaluated against the black mold-causing fungus Aspergillus niger. The produced structures exhibit dose-dependent antifungal activity. Therefore, they could potentially be employed for the protection and preservation of cultural heritage artifacts and considered as new agents for food protection from fungal contamination during storage. View Full-Text
Keywords: silver nanoparticles; poly (methacrylic acid) microspheres; antifungal activity; cultural heritage; food preservation or packaging silver nanoparticles; poly (methacrylic acid) microspheres; antifungal activity; cultural heritage; food preservation or packaging
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MDPI and ACS Style

Kainourgios, P.; Tziveleka, L.-A.; Kartsonakis, I.A.; Ioannou, E.; Roussis, V.; Charitidis, C.A. Silver Nanoparticles Grown on Cross-Linked Poly (Methacrylic Acid) Microspheres: Synthesis, Characterization, and Antifungal Activity Evaluation. Chemosensors 2021, 9, 152. https://doi.org/10.3390/chemosensors9070152

AMA Style

Kainourgios P, Tziveleka L-A, Kartsonakis IA, Ioannou E, Roussis V, Charitidis CA. Silver Nanoparticles Grown on Cross-Linked Poly (Methacrylic Acid) Microspheres: Synthesis, Characterization, and Antifungal Activity Evaluation. Chemosensors. 2021; 9(7):152. https://doi.org/10.3390/chemosensors9070152

Chicago/Turabian Style

Kainourgios, Panagiotis, Leto-Aikaterini Tziveleka, Ioannis A. Kartsonakis, Efstathia Ioannou, Vassilios Roussis, and Costas A. Charitidis 2021. "Silver Nanoparticles Grown on Cross-Linked Poly (Methacrylic Acid) Microspheres: Synthesis, Characterization, and Antifungal Activity Evaluation" Chemosensors 9, no. 7: 152. https://doi.org/10.3390/chemosensors9070152

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