Next Article in Journal
Development of a NanoMIPs-SPR-Based Sensor for β-Lactoglobulin Detection
Previous Article in Journal
Electrical and Humidity-Sensing Properties of Impedance-Type Humidity Sensors that Were Made of Ag Microwires/PPy/SnO2 Ternary Composites
Open AccessArticle

All-Solid-State Calcium Sensors Modified with Polypyrrol (PPY) and Graphene Oxide (GO) as Solid-Contact Ion-to-Electron Transducers

1
Chemistry Department, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia
2
Department of Chemistry, Faculty of Science, Ain Shams University, Cairo 11566, Egypt
3
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
4
Applied Organic Chemistry Department, National Research Center, Dokki, Giza 12622, Egypt
*
Author to whom correspondence should be addressed.
Chemosensors 2020, 8(4), 93; https://doi.org/10.3390/chemosensors8040093
Received: 17 August 2020 / Revised: 3 September 2020 / Accepted: 26 September 2020 / Published: 30 September 2020
(This article belongs to the Section Applied Chemical Sensors)
Reliable, cost-effective, and robust screen-printed sensors were constructed and presented for Ca2+ ions determination. The sensors were based on the use of bilirubin (1,3,6,7-tetramethyl-4,5- dicarboxyethy-2,8-divinyl-(b-13)-dihydrobilenone) as a recognition sensory material in plasticized poly (vinyl chloride) (PVC) membranes. Polypyrrol (PPY) and graphene oxide (GO) were used as ion-to-electron transducers, where the effects of anionic excluder, pH, and selectivity were investigated. In a 50 mM tris buffer solution of pH 5, the electrodes offered a potential response for Ca2+ ions with a near-Nernstian slopes of 38.1 ± 0.4 (r2 = 0.996) and 31.1 ± 0.6 (r2 = 0.999), detection limits 3.8 × 10−6 (0.152 μg/mL) and 2.3 × 10−7 M (8.0 ng/mL), and linear concentration ranges of 7.0 × 10−6–1.0 × 10−2 (400–0.28 μg/mL) and 7.0 × 10−7–1.0 × 10−2 M (400–0.028 μg/mL) for sensors based on PPY and GO, respectively. Both sensors revealed stable potentiometric responses with excellent reproducibility and enhanced selectivity over a number of most common metal ions, such as Na+, K+, Li+, NH4+, Fe2+, Mg2+, and Ba2+. Impedance spectroscopy and chronopotentiometric techniques were used for evaluating the potential drift and the interfacial sensor capacitance. The proposed sensors offered the advantages of simple design, ability of miniaturization, good potential stability, and cost-effectiveness. The developed electrodes were applied successfully to Ca2+ ion assessment in different pharmaceutical products, baby-food formulations, and human blood samples. The results obtained were compared with data obtained by atomic absorption spectrometry (AAS). View Full-Text
Keywords: potentiometric sensors; screen-printed electrodes; polypyrrol (PPY); graphene oxide (GO); chronopotentiometry; impedance spectroscopy potentiometric sensors; screen-printed electrodes; polypyrrol (PPY); graphene oxide (GO); chronopotentiometry; impedance spectroscopy
Show Figures

Figure 1

MDPI and ACS Style

Abd-Rabboh, H.S.M.; H. Kamel, A.; Amr, A.E.-G. All-Solid-State Calcium Sensors Modified with Polypyrrol (PPY) and Graphene Oxide (GO) as Solid-Contact Ion-to-Electron Transducers. Chemosensors 2020, 8, 93.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop