Continuous Glucose Monitoring in Hypoxic Environments Based on Water Splitting-Assisted Electrocatalysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Sensor Fabrication
2.3. In Vitro Glucose Detection
2.4. In Vitro Cytotoxicity Tests
2.5. In Vivo Biocompatibility Test
2.6. Glucose Detection in Normal Rat
2.7. Animal Models
3. Results and Discussion
3.1. Electrochemical Performance of the Sensor In Vitro
3.2. Cytotoxicity and Biocompatibility Test
3.3. Glucose Detection in Normal Rat
3.4. Glucose Detection in Systemic Hypoxic Rat
3.5. Glucose Detection in Local Tissue Hypoxic Mice
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Lei, L.; Xu, C.; Dong, X.; Ma, B.; Chen, Y.; Hao, Q.; Zhao, C.; Liu, H. Continuous Glucose Monitoring in Hypoxic Environments Based on Water Splitting-Assisted Electrocatalysis. Chemosensors 2023, 11, 149. https://doi.org/10.3390/chemosensors11020149
Lei L, Xu C, Dong X, Ma B, Chen Y, Hao Q, Zhao C, Liu H. Continuous Glucose Monitoring in Hypoxic Environments Based on Water Splitting-Assisted Electrocatalysis. Chemosensors. 2023; 11(2):149. https://doi.org/10.3390/chemosensors11020149
Chicago/Turabian StyleLei, Lanjie, Chengtao Xu, Xing Dong, Biao Ma, Yichen Chen, Qing Hao, Chao Zhao, and Hong Liu. 2023. "Continuous Glucose Monitoring in Hypoxic Environments Based on Water Splitting-Assisted Electrocatalysis" Chemosensors 11, no. 2: 149. https://doi.org/10.3390/chemosensors11020149