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Review

Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic

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Genomtec S.A., ul. Stabłowicka 147, 54-066 Wrocław, Poland
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Oral Pathology Department, Faculty of Dentistry, Wroclaw Medical University, ul. Krakowska 26, 50-425 Wrocław, Poland
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Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, ul. Rudolfa Weigla 12, 53-114 Wrocław, Poland
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Department of Molecular Techniques, Faculty of Medicine, Wroclaw Medical University, ul. M. Curie-Skłodowskiej 52, 50-369 Wrocław, Poland
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Author to whom correspondence should be addressed.
Academic Editor: Joaquim Carreras
Healthcare 2021, 9(7), 915; https://doi.org/10.3390/healthcare9070915
Received: 27 April 2021 / Revised: 9 July 2021 / Accepted: 12 July 2021 / Published: 19 July 2021
(This article belongs to the Special Issue COVID-19 Pandemic: Challenges Facing the Health System)
Since the 2019 novel coronavirus outbreak began in Wuhan, China, diagnostic methods in the field of molecular biology have been developing faster than ever under the vigilant eye of world’s research community. Unfortunately, the medical community was not prepared for testing such large volumes or ranges of biological materials, whether blood samples for antibody immunological testing, or salivary/swab samples for real-time PCR. For this reason, many medical diagnostic laboratories have made the switch to working in the field of molecular biology, and research undertaken to speed up the flow of samples through laboratory. The aim of this narrative review is to evaluate the current literature on laboratory techniques for the diagnosis of SARS-CoV-2 infection available on pubmed.gov, Google Scholar, and according to the writers’ knowledge and experience of the laboratory medicine. It assesses the available information in the field of molecular biology by comparing real-time PCR, LAMP technique, RNA sequencing, and immunological diagnostics, and examines the newest techniques along with their limitations for use in SARS-CoV-2 diagnostics. View Full-Text
Keywords: SARS-CoV-2; COVID-19; real-time polymerase chain reaction; LAMP assay SARS-CoV-2; COVID-19; real-time polymerase chain reaction; LAMP assay
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MDPI and ACS Style

Duś-Ilnicka, I.; Szymczak, A.; Małodobra-Mazur, M.; Tokarski, M. Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic. Healthcare 2021, 9, 915. https://doi.org/10.3390/healthcare9070915

AMA Style

Duś-Ilnicka I, Szymczak A, Małodobra-Mazur M, Tokarski M. Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic. Healthcare. 2021; 9(7):915. https://doi.org/10.3390/healthcare9070915

Chicago/Turabian Style

Duś-Ilnicka, Irena, Aleksander Szymczak, Małgorzata Małodobra-Mazur, and Miron Tokarski. 2021. "Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic" Healthcare 9, no. 7: 915. https://doi.org/10.3390/healthcare9070915

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