Invisible Wounds: A Systematic Review of Domestic Violence Against Women
Abstract
1. Introduction
2. Materials and Methods
2.1. Eligibility Criteria
2.2. Information Sources
2.3. Search Strategy
2.4. Selection Process
2.5. Data Collection Process
2.6. Data Items
2.7. Risk of Bias
2.8. Approach to Evidence Synthesis
3. Results
3.1. Overview of Included Studies
3.2. Population Characteristics
3.3. Assessment Method, Prevalence and Patterns of Intimate Partner Violence
3.4. Mental Health and Health-Related Outcomes
3.5. Healthcare Utilization and System Burden
3.6. Intervention and Screening-Related Evidence
3.7. Risk of Bias in Included Studies
4. Discussion
Strengths and Limitations
5. Conclusions
5.1. Evidence-Based Conclusions
5.2. Policy and Practice Implications
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| AUC | Area Under the Curve |
| DV | Domestic Violence |
| DEV | Documented Experience of Violence |
| ED | Emergency Department |
| FGM | Female Genital Mutilation |
| IPV | Intimate Partner Violence |
| MeSH | Medical Subject Headings |
| PCL-C | the PTSD Checklist-Civilian Version |
| PHQ-9 | Patient Health Questionnaire-9 |
| PTSD | Post-Traumatic Stress Disorder |
| WHO | World Health Organization |
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| Age Group | Key Statistics |
|---|---|
| Early and Middle Childhood (0–9 years) | - Over 67 million girls (aged 20–24 years) were married before the age of 18. - >125 million girls in 29 countries have undergone female genital mutilation (FGM) - 20% of girls and 5–10% of boys experience child sexual abuse. - 25% of children experience physical violence and 36% emotional violence. - 42% of girls and 37% of boys have been bullied by peers in the past 30 days. |
| Adolescence (10–19 years) | - 1 in 3 girls (aged 15–49 years) experienced physical and/or sexual violence by an intimate partner. - An estimated 7% of girls have been sexually assaulted by someone other than a partner since age 15. - 1 in 2 children and 1 in 4 have experienced a physical fight with peers in the past year. |
| Youth (20–24 years) | - An estimated 11.4 million women and girls have been trafficked. |
| Adult (25–49 years) | - 38% of homicides against women and 6% of homicides against men are perpetrated by intimate partners. - Millions of people receive hospital care for injuries each year. |
| Older (49+ years) | - 6% of older people reported abuse in the past month. |
| (A) | ||||||
|---|---|---|---|---|---|---|
| Study | Year | Country | Design | Population | Sample Size | IPV Type/Violence Assessed |
| Cabrales-Tejeda et al. [18] | 2023 | Mexico | Prospective cross-sectional | Women attending gynecology clinic | 325 | Physical, psychological, sexual, emotional IPV |
| Kishton et al. [19] | 2022 | USA | Retrospective cohort (claims data) | Women with IPV-related insurance claims | 10,980 | Documented experience of violence (DEV) |
| Ghafournia & Healey [20] | 2022 | Australia | Retrospective cross-sectional | Women presenting to regional ED | 161 | Domestic violence & sexual assault |
| Baker et al. [21] | 2021 | USA | Cross-sectional survey | Incarcerated women in trauma therapy | 115 | Interpersonal & non-interpersonal trauma |
| Charak et al. [22] | 2023 | UK | Cross-sectional (latent class analysis) | Trauma-exposed national adult panel | 1091 | Multiple interpersonal violence forms |
| Daugherty et al. [23] | 2022 | USA | Cross-sectional survey | Female IPV survivors (shelters/online) | 93 | Intimate partner violence |
| Ford-Gilboe et al. [24] | 2020 | Canada | RCT | Women experiencing IPV (past 6 months) | 462 | IPV (any type) |
| Guiguet-Auclair et al. [25] | 2022 | France | Multicenter case–control | Women in relationships ≥ 12 months | 361 | IPV (validated WAST) |
| Bentley et al. [26] | 2022 | Spain | Cross-sectional | Migrant women using support services | 563 | Physical, sexual, psychological IPV |
| Chaquila et al. [27] | 2023 | Peru | Cross-sectional national analysis | Women aged 15–49 | 18,621 | Physical, sexual, emotional IPV |
| Agde et al. [28] | 2024 | Ethiopia | RCT | Pregnant women & husbands (rural) | 864 | Physical, psychological, sexual IPV |
| Barata et al. [29] | 2025 | Canada | RCT (SARE/EAAA) | First-year university women | 153 women/206 relationships | Emotional, physical, severe IPV, harassment |
| Crespo et al. [30] | 2025 | Spain | RCT (secondary analysis) | Survivors receiving trauma-focused CBT | 148 | Psychological, physical, sexual, economic IPV |
| Gibson et al. [31] | 2020 | Ethiopia | Randomization experiment | Rural adults (men & women) | 809 | Attitudes toward physical IPV |
| Kelly et al. [32] | 2024 | South Africa | Longitudinal cohort | Adolescent girls & young women | 2183 | Physical IPV |
| Mahapatro et al. [33] | 2024 | India | RCT | Pregnant married women | 211 | Physical, psychological, sexual IPV |
| Panjaphothiwat et al. [34] | 2025 | Thailand | Cross-sectional | Pregnant women (COVID-19 period) | 496 | Psychological, physical, sexual IPV |
| Taft et al. [35] | 2025 | Australia | Cluster RCT | Adult women in general practice | 45,438 | Physical, emotional, psychological, sexual, financial IPV |
| (B) | ||||||
| Study | IPV Prevalence/Key Outcomes | Assessment Method | Mental Health Outcomes | Risk Factors/Other Findings | Limitations | |
| Cabrales-Tejeda et al. [18] | IPV ever: 52% | No standardized mental health instrument used; study focused on IPV prevalence and associated risk factors | — | Childhood abuse, jealousy, substance use, economic stress | Single site; self-report | |
| Kishton et al. [19] | Higher ER (aOR 2.6) & inpatient use (aOR 2.2) | Administrative diagnostic codes for mental health and substance use disorders derived from insurance claims data | ↑ MH & substance use diagnoses | Increased healthcare costs | Insurance-based; coding limits | |
| Ghafournia & Healey [20] | >50% recurrent ED visits | Clinical symptom documentation from emergency department records; no validated psychometric scales specified | Strong link with MH symptoms | Pregnancy and Indigenous status high-risk | Small sample; single ED | |
| Baker et al. [21] | High cumulative trauma exposure | Validated self-report psychometric scales assessing depression, PTSD, distress tolerance, guilt, and shame (battery of standardized trauma-related instruments) | ↑ Depression, PTSD, anxiety | Interpersonal trauma predictive | Prison sample; recall bias | |
| Charak et al. [22] | Polyvictimization: high IPV class | Life Events Checklist for trauma exposure and standardized measures of depression, anxiety, and DSM-5 PTSD symptoms, including diagnostic classification | ↑ Depression (9×), anxiety (12×), PTSD (33×) | Victimization clustering | Self-report; cross-sectional | |
| Daugherty et al. [23] | High abuse severity | PHQ-9 (depression), PCL-5 (PTSD), GAD-7 (anxiety), and Neuro-QOL Executive Function scale | ↓ Executive functioning | PTSD and abuse severity predict EF impairment | Small; no objective testing | |
| Ford-Gilboe et al. [24] | Longitudinal improvements in IPV-related symptoms | Validated depression and PTSD symptom scales assessed longitudinally at baseline, 3, 6, and 12 months | ↓ Depression and PTSD over 12 months | Tailored intervention helps severe cases | No true control group | |
| Guiguet-Auclair et al. [25] | WAST AUC: 0.99; sensitivity 97.7% | Women Abuse Screening Tool (WAST) only; mental health outcomes not assessed | — | Self-administered preferred | Some sampling bias | |
| Bentley et al. [26] | IPV: 78% | PHQ-9 (depression) and GAD-7 (anxiety) in a large population-based migrant sample | Depression, PTSD associated | Psychological + comorbid IPV highest burden | Support-seeking bias | |
| Chaquila et al. [27] | IPV: 15.4% | PHQ-9 (depressive symptoms) derived from nationally validated ENDES survey data | Depressive symptoms: 27.1% | Wealth modifies IPV-depression link | No childhood abuse data | |
| Agde et al. [28] | IPV knowledge > 50% | None—IPV knowledge/attitudes measured via adapted structured questionnaire; no validated mental health instrument used | — | Education, antenatal care protective | Baseline cross-section only | |
| Barata et al. [29] | 54% reduction in IPV (intervention) | Not assessed; intervention study evaluating IPV reduction following a sexual assault resistance program (EAAA) | — | Effects extended to emotional & physical IPV | Single IPV measurement | |
| Crespo et al. [30] | High dropout (45%) | PTSD, depression, anxiety assessed using EGEP-5, BDI-II, BAI, PANAS, DERS | ↑ Anxiety predicts dropout | Employment instability; recent IPV | Single therapist; small sample | |
| Gibson et al. [31] | IPV acceptance: 18% (direct) vs. 28% (indirect) | Attitudes toward IPV assessed via list randomization experiment | — | Low education, male-controlled finances ↑ acceptance | Cultural sensitivity issues | |
| Kelly et al. [32] | High-risk trajectory: 26.7% | Perceived stress (Cohen Stress Scale) and biomarkers | ↑ CRP inflammatory biomarker | Cash transfers buffer stress–IPV link | Stress measured once | |
| Mahapatro et al. [33] | Severe IPV ↓ by 90% post-intervention | Quality of life via SF-36; DV via AAST | ↑ QoL across domains | Slight improvements in RCH outcomes | No follow-up; self-report | |
| Panjaphothiwat et al. [34] | IPV: 15.5% | Mental health inferred via validated DV questionnaire (Cronbach α ≈ 0.70); no diagnostic tools | ↑ Depression | Low income, unintended pregnancy, alcohol use | Underreporting likely | |
| Taft et al. [35] | IPV identified: 0.58% | Mental health inferred from GP records and algorithm-based DVA identification | — | South Asian women under-identified | Coding limitations; no consent | |
| Study | Design | RoB Tool Used | Overall RoB | Key Concerns |
|---|---|---|---|---|
| Cabrales-Tejeda et al. [18] | Prospective, analytical cross-sectional, single tertiary gynecology clinic | JBI—Analytical Cross-sectional | Some concerns/moderate (3) | Convenience sample from one hospital; reliance on self-reported IPV; limited adjustment for confounders; generalizability restricted to similar clinical settings. |
| Kishton et al. [19] | Retrospective cohort using private insurance claims | ROBINS-I | Some concerns/moderate (3) | Selection restricted to privately insured women; IPV identified through ICD codes (possible misclassification); residual confounding likely despite adjustments; good internal consistency of claims data. |
| Ghafournia & Healey [20] | Retrospective cross-sectional, single regional ED | JBI—Analytical cross-sectional | Some concerns/moderate (3) | Single emergency department; relatively small sample; potential under-reporting of IPV/SA; limited exploration of non-attenders; outcome and exposure based on routine documentation and self-report. |
| Baker et al. [21] | Cross-sectional survey among incarcerated women | JBI—Analytical cross-sectional | High/serious (4) | Highly selected, treatment-seeking prison sample; trauma histories measured retrospectively with limited event detail; frequency and timing of trauma not captured; multiple unmeasured confounders (e.g., lifetime psychiatric comorbidity). |
| Charak et al. [22] | Cross-sectional latent class analysis in national trauma-exposed panel | JBI—Analytical cross-sectional | Some concerns/moderate (3) | Online panel may exclude non-digital or marginalized groups; self-reported victimization and mental health; cross-sectional design precludes causal inference; no detailed racial/ethnic data. |
| Daugherty et al. [23] | Cross-sectional survey of IPV survivors (shelters and online) | JBI—Analytical cross-sectional | High/serious (4) | Small sample; recruitment from shelters and online platforms (strong selection bias); perceived executive functioning and symptoms based solely on self-report; no objective neuropsychological testing; cross-sectional design. |
| Ford-Gilboe et al. [24] | RCT of online safety and health intervention for women experiencing IPV | RoB 2 | Some concerns (2) | Lack of a “no-intervention” control (comparison of tailored vs. non-tailored versions); self-selected online, English-speaking sample; outcomes based on self-reported symptoms; possible “survey-as-intervention” effect. |
| Guiguet-Auclair et al. [25] | Multicenter case–control validation of the French WAST | JBI—Case–control checklist | Low (1) | Clear inclusion criteria; appropriate measurement of exposure (WAST) and outcome (IPV status); excellent psychometric performance; some sampling bias in controls (partly recruited from investigators’ circles) but unlikely to substantially affect internal validity. |
| Bentley et al. [26] | Cross-sectional, observational study of migrant women in Spain | JBI—Analytical cross-sectional | Some concerns/moderate (3) | Support-seeking migrant sample (selection bias); reliance on self-reported IPV and mental health; cross-sectional analysis limits causal interpretation; limited adjustment for contextual migration-related factors. |
| Chaquila et al. [27] | Cross-sectional analysis of national survey of Peruvian women | JBI—Analytical cross-sectional | Some concerns/moderate (3) | IPV and depressive symptoms measured via self-report; cross-sectional design; no data on lifetime or childhood abuse; residual confounding by unmeasured social factors; large, nationally representative sample strengthens external validity. |
| Agde et al. [28] | Cluster RCT in rural Ethiopia (baseline knowledge and attitudes) | RoB 2 | Some concerns (2) | Baseline analysis essentially cross-sectional; self-reported attitudes and knowledge (social desirability bias); limited comparable literature for men; randomization process described but clustering and contextual confounding remain possible. |
| Barata et al. [29] | RCT (SARE/EAAA sexual assault resistance program) with IPV outcomes in first-year university women | RoB 2 | Low (1) | Robust randomized design; PV outcomes measured prospectively over 12 months; some limitations due to small IPV substudy, single measurement of IPV, and limited diversity (mostly white, heterosexual students) but low risk of major internal bias. |
| Crespo et al. [30] | RCT (secondary analysis) of trauma-focused CBT for survivors of IPVAW | RoB 2 | High/serious (4) | High overall dropout (45%), especially in first sessions; small sample size; single therapist delivering both conditions; reasons for dropout partly self-reported and prone to bias; limited power to detect differences between treatment arms. |
| Gibson et al. [31] | Randomization experiment (list experiment) on attitudes towards wife-beating in rural Ethiopia | RoB 2 | Low (1) | Random assignment to direct vs. indirect questioning; appropriate handling of list experiment; main limitation is small size of some subgroups and cultural sensitivity of topic; overall internal validity is strong for the main attitudinal outcome. |
| Kelly et al. [32] | Longitudinal cohort of adolescent girls and young women in South Africa | ROBINS-I | Some concerns/moderate (3) | Physical IPV measured repeatedly via self-report; sparse data in older ages; some biomarkers assessed only once; possible residual confounding despite detailed data; large sample and longitudinal design strengthen temporal inference. |
| Mahapatro et al. [33] | RCT of behavioral intervention package for pregnant women experiencing IPV | RoB 2 | Some concerns (2) | Randomization described; outcomes based on self-reported IPV severity and QoL; only post-intervention measurement (no long-term follow-up); no partner data; conducted in one public tertiary hospital among low-income women, limiting generalizability. |
| Panjaphothiwat et al. [34] | Cross-sectional descriptive study of IPV in pregnant women during COVID-19 | JBI—Analytical cross-sectional | Some concerns/moderate (3) | Self-reported IPV in antenatal setting; cross-sectional design; under-reporting likely due to stigma; limited exploration of non-attenders; nonetheless, sampling frame and measurement are described. |
| Taft et al. [35] | Cluster RCT in Australian general practice (baseline IPV identification data) | RoB 2 | Some concerns (2) | Baseline data derived from routine electronic medical records; algorithm-based identification likely underdetects IPV; no individual patient consent; limited information on completeness and accuracy of EMR coding; clustering and ethnic disparities in recording acknowledged. |
| Outcome Domain | Low or Moderate Risk Studies | High-Risk Studies | Interpretation |
|---|---|---|---|
| IPV prevalence (population and clinical samples) | Chaquila et al. [27] (moderate); Cabrales-Tejeda et al. [18] (moderate); Kishton et al. [19] (moderate); Guiguet-Auclair et al. [25] (low) | Baker et al. [21] (high); Crespo et al. [30] (high) | Robust conclusion: IPV is common across populations. Exploratory: extremely high prevalence reflects selection of extreme-risk groups |
| Depression associated with IPV | Charak et al. [22] (moderate); Bentley et al. [26] (moderate); Chaquila et al. [27] (moderate); Ford-Gilboe et al. [24] (moderate) | Baker et al. [21] (high) | Robust conclusion: IPV–depression association consistent across designs |
| PTSD associated with IPV | Charak et al. [22] (moderate); Bentley et al. [26] (moderate); Ford-Gilboe et al. [24] (moderate) | Baker et al. [21] (high) | Robust conclusion: IPV is a strong risk factor for PTSD. Exploratory: near-universal PTSD in incarcerated samples |
| Anxiety and suicidality | Charak et al. [22] (moderate); Crespo et al. [30] (high) (partial) | Baker et al. [21] (high) | Moderately robust: anxiety association supported; suicidality severity mainly from high-risk samples |
| Cognitive/executive dysfunction | — | Daugherty et al. [23] (high) | Exploratory only: hypothesis-generating evidence |
| Healthcare utilization and costs | Kishton et al. [19] (moderate); Taft et al. [35] (moderate) | Ghafournia & Healey [20] (moderate) (small sample) | Robust conclusion: IPV associated with increased healthcare utilization and under-detection |
| Biological stress markers | Kelly et al. [32] (moderate) | — | Moderately robust: supported by longitudinal design, limited replication |
| Effectiveness of interventions | Barata et al. [29] (low); Mahapatro et al. [33] (moderate); Ford-Gilboe et al. [24] (moderate) | Crespo et al. [30] (high) | Robust conclusion: interventions reduce IPV-related harm |
| Screening and identification of IPV | Guiguet-Auclair et al. [25] (low); Taft et al. [35] (moderate) | — | Robust conclusion: validated tools perform well; IPV remains under-identified |
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Deacu, S.; Cristian, M.; Popa, S.I.; Nitu, R.A.; Pricop, S. Invisible Wounds: A Systematic Review of Domestic Violence Against Women. Healthcare 2026, 14, 465. https://doi.org/10.3390/healthcare14040465
Deacu S, Cristian M, Popa SI, Nitu RA, Pricop S. Invisible Wounds: A Systematic Review of Domestic Violence Against Women. Healthcare. 2026; 14(4):465. https://doi.org/10.3390/healthcare14040465
Chicago/Turabian StyleDeacu, Sorin, Miruna Cristian, Sabina Ioana Popa, Radu Adrian Nitu, and Stefan Pricop. 2026. "Invisible Wounds: A Systematic Review of Domestic Violence Against Women" Healthcare 14, no. 4: 465. https://doi.org/10.3390/healthcare14040465
APA StyleDeacu, S., Cristian, M., Popa, S. I., Nitu, R. A., & Pricop, S. (2026). Invisible Wounds: A Systematic Review of Domestic Violence Against Women. Healthcare, 14(4), 465. https://doi.org/10.3390/healthcare14040465

