Relationship Between Perceived Stress and Anxiety in High School Senior Students: The Mediating Role of Social Support and the Moderating Influence of Lifestyle
Abstract
1. Introduction
Aims and Hypotheses
2. Materials and Methods
2.1. Study Design
2.2. Study Participants and Procedure
2.3. Perceived Stress (PSS-10)
2.4. Generalized Anxiety Disorder Scale (GAD-7)
2.5. Multidimensional Scale of Perceived Social Support (MPSSS)
2.6. International Physical Activity Questionnaire (IPAQ Short)
2.7. Alcohol Use Disorders Identification Test (AUDIT)
2.8. Fagerström Test for Nicotine Dependence (FTND)
2.9. Statistical Analysis
3. Results
3.1. Descriptive and Correlational Analysis
3.2. Hierarchical Multiple Regression Analysis
3.3. Mediation Analysis
3.4. Moderation Analysis
4. Discussion
Strengths and Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Wuthrich, V.M.; Jagiello, T.; Azzi, V. Academic stress in the final years of school: A systematic literature review. Child Psychiatry Hum. Dev. 2020, 51, 986–1015. [Google Scholar] [CrossRef]
- Grant, K.E.; Compas, B.E.; Thurm, A.E.; McMahon, S.D.; Gipson, P.Y. Stressors and child and adolescent psychopathology: Measurement issues and prospective effects. J. Clin. Child Adolesc. Psychol. 2004, 33, 412–425. [Google Scholar] [CrossRef]
- Panchal, U.; de Pablo, G.S.; Franco, M.; Moreno, C.; Parellada, M.; Arango, C.; Fusar-Poli, P. The Impact of COVID-19 lockdown on child and adolescent mental health: Systematic review. Eur. Child. Adolesc. Psychiatry 2023, 32, 1151–1177. [Google Scholar] [CrossRef] [PubMed]
- Anderson, T.L.; Valiauga, R.; Tallo, C.; Hong, C.B.; Manoranjithan, S.; Domingo, C.; Paudel, M.; Untaroiu, A.; Barr, S.; Goldhaber, K. Contributing factors to the rise in adolescent anxiety and associated mental health disorders: A narrative review of current literature. J. Child Adolesc. Psychiatr. Nurs. 2025, 38, e70009. [Google Scholar] [CrossRef]
- Brown, M.L. Integrative approaches to stress, anxiety, and resilience. Pediatr. Ann. 2019, 48, e226–e230. [Google Scholar] [CrossRef]
- Spence, S.H.; Lawrence, D.; Zubrick, S.R. Anxiety trajectories in adolescents and the impact of social support and peer victimization. Res. Child Adolesc. Psychopathol. 2022, 50, 795–807. [Google Scholar] [CrossRef] [PubMed]
- Fernández Lasarte, O.; Ramos Díaz, E.; Goñi Palacios, E.; Rodríguez Fernández, A. The role of social support in school adjustment during secondary education. Psicothema 2020, 32, 100–107. [Google Scholar] [CrossRef] [PubMed]
- Asensio-Martínez, A.; Aguilar-Latorre, A.; Masluk, B.; Gascón-Santos, S.; Sánchez-Calavera, M.A.; Sánchez-Recio, R. Social Support as a Mediator in the Relationship between Technostress or Academic Stress and Health: Analysis by Gender among University Students. Front. Psychol. 2023, 14, 1236825. [Google Scholar] [CrossRef]
- Acoba, E.F. Social support and mental health: The mediating role of perceived stress. Front. Psychol. 2024, 15, 1330720. [Google Scholar] [CrossRef]
- Yarcheski, A.; Mahon, N.E. The moderator-mediator role of social support in early adolescents. West. J. Nurs. Res. 1999, 21, 685–698. [Google Scholar] [CrossRef]
- Bedaso, A.; Adams, J.; Peng, W.; Sibbritt, D. The Mediational Role of Social Support in the Relationship between Stress and Antenatal Anxiety and Depressive Symptoms among Australian Women: A Mediational Analysis. Reprod. Health 2021, 18, 250. [Google Scholar] [CrossRef]
- Lazarus, R.; Folkman, S. Stress, Appraisal, and Coping; Springer: New York, NY, USA, 1984. [Google Scholar]
- Metzger, I.W.; Blevins, C.; Calhoun, C.D.; Ritchwood, T.D.; Gilmore, A.K.; Stewart, R.; Bountress, K.E. An examination of the impact of maladaptive coping on the association between stressor type and alcohol use in college. J. Am. Coll. Health 2017, 65, 534–541. [Google Scholar] [CrossRef]
- Terlecki, M.; Ecker, A.; Buckner, J. Drinking context influences the association between social anxiety and drinking problems in undergraduates. Psychol. Addict. Behav. 2014, 28, 545–552. [Google Scholar] [CrossRef]
- Sayette, M.A. The effects of alcohol on emotion in social drinkers. Behav. Res. Ther. 2017, 88, 76–89. [Google Scholar] [CrossRef]
- Anker, J.J.; Kushner, M.G. Co-occurring alcohol use disorder and anxiety: Bridging psychiatric, psychological, and neurobiological perspectives. Alcohol Res. 2019, 40, arcr.v40.1.03. [Google Scholar] [CrossRef]
- El Ansari, W.; Salam, A.; Suominen, S. Is alcohol consumption associated with poor perceived academic performance? Survey of undergraduates in Finland. Int. J. Environ. Res. Public Health 2020, 17, 1369. [Google Scholar] [CrossRef]
- Ummels, S.A.; Seldenrijk, A.; Bos, E.H.; de Graaf, R.; Batelaan, N.M.; Ten Have, M. The bidirectional relationship between anxiety disorders and alcohol use disorders in adults: Findings from a longitudinal population-based study. J. Affect. Disord. 2022, 314, 126–132. [Google Scholar] [CrossRef] [PubMed]
- Buckner, J.D.; Vinci, C. Smoking and social anxiety: The roles of gender and smoking motives. Addict. Behav. 2013, 38, 2388–2391. [Google Scholar] [CrossRef] [PubMed]
- Yan, Y.; Sun, S.; Deng, S.; Jiang, J.; Duan, F.; Song, C.; Wang, K.; Zhang, N.; Tian, Q.; Nie, W. A systematic review of anxiety across smoking stages in adolescents and young adults. Subst. Use Misuse 2019, 54, 1408–1415. [Google Scholar] [CrossRef] [PubMed]
- Moylan, S.; Gustavson, K.; Karevold, E.; Øverland, S.; Jacka, F.N.; Pasco, J.A.; Berk, M. The impact of smoking in adolescence on early adult anxiety symptoms and the relationship between infant vulnerability factors for anxiety and early adult anxiety symptoms: The TOPP Study. PLoS ONE 2013, 8, e63252. [Google Scholar] [CrossRef]
- Siqueira, L.; Diab, M.; Bodian, C.; Rolnitzky, L. Adolescents becoming smokers: The roles of stress and coping methods. J. Adolesc. Health 2000, 27, 399–408. [Google Scholar] [CrossRef]
- Panza, M.J.; Graupensperger, S.; Agans, J.P.; Doré, I.; Vella, S.A.; Evans, M.B. Adolescent sport participation and symptoms of anxiety and depression: A systematic review and meta-analysis. J. Sport Exerc. Psychol. 2020, 42, 201–218. [Google Scholar] [CrossRef] [PubMed]
- Liu, P. Stress buffering effects of physical activity in adolescents: The moderating role of physical activity attitudes. BMC Public Health 2025, 25, 463. [Google Scholar] [CrossRef]
- Velki, T. Can physical activities suppress negative impact of stress on the mental health of adolescents? Int. J. Ment. Health Promot. 2024, 26, 211–219. [Google Scholar] [CrossRef]
- Solmaz, S.; İnan, M.; Şahin, M.Y. The moderating effects of physical activity on social anxiety and sleep disturbance: Managing gaming disorder in young e-sports players. Front. Public Health 2025, 13, 1544044. [Google Scholar] [CrossRef]
- Wu, J.; Shao, Y.; Zang, W.; Hu, J. Is physical exercise associated with reduced adolescent social anxiety mediated by psychological resilience? Evidence from a longitudinal multi-wave study in China. Child Adolesc. Psychiatry Ment. Health 2025, 19, 17. [Google Scholar] [CrossRef] [PubMed]
- Klaperski, S.; Von Dawans, B.; Heinrichs, M.; Fuchs, R. Does the level of physical exercise affect physiological and psychological responses to psychosocial stress in women? Psychol. Sport. Exerc. 2013, 14, 266–274. [Google Scholar] [CrossRef]
- Zhang, G.; Feng, W.; Zhao, L.; Zhao, X.; Li, T. The association between physical activity, self-efficacy, stress self-management and mental health among adolescents. Sci. Rep. 2024, 14, 5488. [Google Scholar] [CrossRef]
- Jelleli, H.; Ben Aissa, M.; Kaddech, N.; Saidane, M.; Guelmami, N.; Bragazzi, N.L.; Bonsaksen, T.; Fekih-Romdhane, F.; Dergaa, I. Examining the interplay between physical activity, problematic internet use and the negative emotional state of depression, anxiety and stress: Insights from a moderated mediation path model in university students. BMC Psychol. 2024, 12, 406. [Google Scholar] [CrossRef]
- Vaičiūnas, T.; Žemaitaitytė, M.; Lange, S.; Štelemėkas, M.; Oja, L.; Petkevičienė, J.; Kowalewska, A.; Pudule, I.; Piksööt, J.; Šmigelskas, K. Trends in Adolescent Substance Use: Analysis of HBSC Data for Four Eastern European Countries, 1994–2018. Int. J. Environ. Res. Public Health 2022, 19, 15457. [Google Scholar] [CrossRef]
- Fairchild, A.J.; MacKinnon, D.P. A general model for testing mediation and moderation effects. Prev. Sci. 2009, 10, 87–99. [Google Scholar] [CrossRef]
- Maxwell, S.E.; Delaney, H.D.; Kelley, K. Designing Experiments and Analyzing Data: A Model Comparison Perspective, 3rd ed.; Routledge: New York, NY, USA, 2018. [Google Scholar] [CrossRef]
- Ryu, E.; West, S.G.; Sousa, K.H. Mediation and moderation: Testing relationships between symptom status, functional health, and quality of life in HIV patients. Multivar. Behav. Res. 2009, 44, 213–232. [Google Scholar] [CrossRef]
- Chai, X.; Tan, Y.; Dong, Y. An Investigation into Social Determinants of Health Lifestyles of Canadians: A Nationwide Cross-Sectional Study on Smoking, Physical Activity, and Alcohol Consumption. BMC Public Health 2024, 24, 2080. [Google Scholar] [CrossRef]
- Cohen, S.; Kamarck, T.; Mermelstein, R. A global measure of perceived stress. J. Health Soc. Behav. 1983, 24, 385–396. [Google Scholar] [CrossRef]
- Geceviciene, S. Students, Studying Stress and Coping Strategies Correlation with Satisfaction at Studies. Master’s Thesis, Vytautas Magnus University, Kaunas, Lithuania, 2017; pp. 1–69. [Google Scholar]
- Spitzer, R.L.; Kroenke, K.; Williams, J.B.; Löwe, B. A brief measure for assessing generalized anxiety disorder: The GAD-7. Arch. Intern. Med. 2006, 166, 1092–1097. [Google Scholar] [CrossRef] [PubMed]
- Pranckeviciene, A.; Saudargiene, A.; Gecaite-Stonciene, J.; Liaugaudaite, V.; Griskova-Bulanova, I.; Simkute, D.; Naginiene, R.; Dainauskas, L.L.; Ceidaite, G.; Burkauskas, J. Validation of the patient health questionnaire-9 and the generalized anxiety disorder-7 in Lithuanian student sample. PLoS ONE 2022, 17, e0263027. [Google Scholar] [CrossRef]
- Zimet, G.D.; Powell, S.S.; Farley, G.K.; Werkman, S.; Berkoff, K.A. Psychometric characteristics of the multidimensional scale of perceived social support. J. Pers. Assess. 1990, 55, 610–617. [Google Scholar] [CrossRef]
- Canty-Mitchell, J.; Zimet, G.D. Psychometric properties of the multidimensional scale of perceived social support in urban adolescents. Am. J. Community Psychol. 2000, 28, 391–400. [Google Scholar] [CrossRef]
- Vitkauskaitė, S. Association Between Adolescents’ Subjective Perceived Social Support, Sleep Quality and Psychosomatic Complaints. Master’s Thesis, Lithuanian University of Health Sciences, Kaunas, Lithuania, 2024. [Google Scholar]
- Kim, Y.; Park, I.; Kang, M. Convergent validity of the international physical activity questionnaire (IPAQ): Meta-analysis. Public Health Nutr. 2013, 16, 440–452. [Google Scholar] [CrossRef] [PubMed]
- Kalvenas, A.; Burlacu, I.; Abu-Omar, K. Reliability and validity of the international physical activity questionnaire in Lithuania. Balt. J. Health Phys. Act. 2016, 8, 29–41. [Google Scholar] [CrossRef]
- Babor, T.F.; Higgins-Biddle, J.C.; Saunders, J.B.; Monteiro, M.G. The Alcohol Use Disorders Identification Test (AUDIT); World Health Organization: Geneva, Switzerland, 2001.
- Burkauskas, J.; Bunevicius, A.; Steibliene, V.; Podlipskyte, A.; Fineberg, N.A.; Juskiene, J.; Gecaite, J.; Liaugaudaite, V.; Mickuviene, N. Validation of the alcohol use disorders identification test in patients with anxiety and mood disorders in Lithuania. Eur. Neuropsychopharmacol. 2019, 29, S111–S112. [Google Scholar] [CrossRef]
- Heatherton, T.F.; Kozlowski, L.T.; Frecker, R.C.; Fagerström, K.O. The Fagerström test for nicotine dependence: A revision of the Fagerström tolerance questionnaire. Br. J. Addict. 1991, 86, 1119–1127. [Google Scholar] [CrossRef]
- Dambrauskiene, K.; Adomaitiene, V.; Klumbiene, J.; Petkeviciene, J.; Veryga, A. The Fagerström Test for Nicotine Dependence in Lithuanian Adult Smokers. In Proceedings of the Abstracts of the 17th European Congress of Psychiatry, Lisbon, Portugal, 24–28 January 2009; European Psychiatry: Prague, Czech Republic, 2009. [Google Scholar]
- R Core Team. R: A Language and Environment for Statistical Computing, Version 4.2.0; R Foundation for Statistical Computing: Vienna, Austria, 2022. Available online: https://www.R-project.org/ (accessed on 6 July 2024).
- Tingley, D.; Yamamoto, T.; Hirose, K.; Keele, L.; Imai, K. Mediation: R Package for Causal Mediation Analysis. J. Stat. Softw. 2014, 59, 1–38. [Google Scholar] [CrossRef]
- Cohen, J. Statistical Power Analysis for the Behavioral Sciences, 2nd ed.; Lawrence Erlbaum Associates: Hillsdale, NJ, USA, 1988. [Google Scholar]
- Gujarati, D.N. Basic Econometrics, 4th ed.; McGraw-Hill: New York, NY, USA, 2004. [Google Scholar]
- Jaccard, J.; Wan, C.K.; Turrisi, R. The detection and interpretation of interaction effects between continuous variables in multiple regression. Multivar. Behav. Res. 1990, 25, 467–478. [Google Scholar] [CrossRef] [PubMed]
- Corr, R.; Pelletier-Baldelli, A.; Glier, S.; Bizzell, J.; Campbell, A.; Belger, A. Neural mechanisms of acute stress and trait anxiety in adolescents. Neuroimage Clin. 2021, 29, 102543. [Google Scholar] [CrossRef] [PubMed]
- Ghimire, R.; Adhikari Mishra, T.; Sharma, P. Stress anxiety and depression among adolescents of schools in Godawari municipality, Lalitpur. Kathmandu Univ. Med. J. (KUMJ) 2024, 22, 426–432. [Google Scholar] [PubMed]
- He, T.; Tu, C.C.; Wang, Z.; Hao, D.; Huang, X. Potential effect of social support on perceived stress and anxiety in college students during public health crisis: Multiple interactions of gender. PLoS ONE 2025, 20, e0319799. [Google Scholar] [CrossRef]
- Cox, W.M.; Hosier, S.G.; Crossley, S.; Kendall, B.; Roberts, K.L. Motives for drinking, alcohol consumption, and alcohol-related problems among British secondary-school and university students. Addict. Behav. 2006, 31, 2147–2157. [Google Scholar] [CrossRef]
- Patrick, M.E.; Schulenberg, J.E. Prevalence and predictors of adolescent alcohol use and binge drinking in the United States. Alcohol Res. 2013, 35, 193–200. [Google Scholar] [CrossRef]
- Smith, J.P.; Randall, C.L. Anxiety and alcohol use disorders: Comorbidity and treatment considerations. Alcohol Res. 2012, 34, 414–431. [Google Scholar] [CrossRef]
- D’Aquino, S.; Kumar, A.; Riordan, B.; Callinan, S. Long-term effects of alcohol consumption on anxiety in adults: A systematic review. Addict. Behav. 2024, 155, 108047. [Google Scholar] [CrossRef]
- Ramer, N.E.; Colder, C.R. The moderating effects of alcohol use with and without parent permission on alcohol risk communication in early adolescence. Addict. Behav. 2022, 126, 107174. [Google Scholar] [CrossRef]
- McGee, R.; Williams, S.; Nada-Raja, S.; Olsson, C.A. Tobacco smoking in adolescence predicts maladaptive coping styles in adulthood. Nicotine Tob. Res. 2013, 15, 1971–1977. [Google Scholar] [CrossRef]
- McLeish, A.C.; Zvolensky, M.J.; Yartz, A.R.; Leyro, T.M. Anxiety sensitivity as a moderator of the association between smoking status and anxiety symptoms and bodily vigilance: Replication and extension in a young adult sample. Addict. Behav. 2008, 33, 315–327. [Google Scholar] [CrossRef]
- Fluharty, M.; Taylor, A.E.; Grabski, M.; Munafò, M.R. The association of cigarette smoking with depression and anxiety: A systematic review. Nicotine Tob. Res. 2017, 19, 3–13. [Google Scholar] [CrossRef] [PubMed]
- Hwang, J.; Borah, P. Anxiety disorder and smoking behavior: The moderating effects of entertainment and informational television viewing. Int. J. Environ. Res. Public Health 2022, 19, 9160. [Google Scholar] [CrossRef] [PubMed]
- Mahindru, A.; Patil, P.; Agrawal, V. Role of physical activity on mental health and well-being: A review. Cureus 2023, 15, e33475. [Google Scholar] [CrossRef] [PubMed]
- Martín-Rodríguez, A.; Gostian-Ropotin, L.A.; Beltrán-Velasco, A.I.; Belando-Pedreño, N.; Simón, J.A.; López-Mora, C.; Navarro-Jiménez, E.; Tornero-Aguilera, J.F.; Clemente-Suárez, V.J. Sporting mind: The interplay of physical activity and psychological health. Sports 2024, 12, 37. [Google Scholar] [CrossRef]




| N = 405 | Skewness | Kurtosis | |||||
|---|---|---|---|---|---|---|---|
| Scale | M | SD | Sk | SkSE | Ku | KuSE | Cronbach α |
| Anxiety (GAD-7) | 10.81 | 5.11 | 0.330 | 0.121 | −0.992 | 0.242 | 0.94 |
| Perceived stress (PSS-10) | 20.91 | 3.31 | 0.069 | 0.121 | 1.998 | 0.242 | 0.92 |
| Perceived social support (MSPSS) | 57.50 | 14.70 | −0.196 | 0.121 | −1.132 | 0.242 | 0.92 |
| Alcohol dependence (AUDIT) | 9.20 | 7.70 | 0.202 | 0.121 | −1.538 | 0.242 | 0.87 |
| Nicotine dependence (FTND) | 2.45 | 2.99 | 0.635 | 0.121 | −1.329 | 0.242 | 0.76 |
| Physical activity (IPAQ) (log(MET-min/week)) | 2.94 | 0.49 | −0.238 | 0.121 | −1.766 | 0.242 | 0.83 |
| Men | Women | |||||
|---|---|---|---|---|---|---|
| N = 149 | N = 256 | |||||
| Scale | M | SD | M | SD | t | d |
| Anxiety (GAD-7) | 12.62 | 5.49 | 9.75 | 4.56 | 5.64 *** | 0.58 |
| Perceived stress (PSS-10) | 21.25 | 3.15 | 20.63 | 3.38 | 1.81 | 0.19 |
| Perceived social support (MSPSS) | 52.26 | 15.17 | 60.55 | 13.55 | −5.68 *** | −0.59 |
| Alcohol dependence (AUDIT) | 12.42 | 8.13 | 7.32 | 6.79 | 6.76 *** | 0.69 |
| Nicotine dependence (FTND) | 3.60 | 3.26 | 1.77 | 2.60 | 6.22 *** | 0.64 |
| Physical activity (IPAQ) (log(MET-min/week)) | 2.09 | 1.40 | 1.22 | 1.49 | 5.87 *** | 0.61 |
| GAD-7 | PSS-10 | MSPSS | AUDIT | FTND | IPAQ | Gender | |
|---|---|---|---|---|---|---|---|
| Anxiety (GAD-7) | 1 | ||||||
| Perceived stress (PSS-10) | 0.486 ** | 1 | |||||
| Social support (MSPSS) | −0.777 ** | −0.362 ** | 1 | ||||
| Alcohol dependence (AUDIT) | 0.773 ** | 0.359 ** | −0.791 ** | 1 | |||
| Nicotine dependence (FTND) | 0.693 ** | 0.334 ** | −0.733 ** | 0.792 ** | 1 | ||
| Physical activity (IPAQ) | −0.284 ** | −0.035 | 0.305 ** | −0.318 ** | −0.276 ** | 1 | |
| Gender | −0.271 ** | −0.090 * | 0.272 ** | −0.319 ** | −0.296 ** | 0.098 * | 1 |
| Model Variables | B | SE(B) | β | t | p | R2 | ΔR2 | Lower 95% CI | Upper 95% CI | |
|---|---|---|---|---|---|---|---|---|---|---|
| Block 1 | Gender | −0.242 | 0.447 | −0.229 | −5.414 | <0.001 | −3.300 | −1.542 | ||
| Perceived stress (PSS-10) | 0.719 | 0.065 | 0.466 | 11.017 | <0.001 | 0.288 | 0.591 | 0.847 | ||
| Block 2 | Gender | −0.698 | 0.322 | −0.066 | −2.167 | 0.031 | −1.331 | −0.065 | ||
| Perceived stress (PSS-10) | 0.365 | 0.049 | 0.236 | 7.515 | <0.001 | 0.269 | 0.460 | |||
| Social support (MSPSS) | −0.234 | 0.011 | −0.673 | −20.703 | <0.001 | 0.656 | 0.368 *** | −0.256 | −0.212 | |
| Block 3 | Gender | −0.278 | 0.306 | −0.026 | −0.911 | 0.363 | −0.879 | 0.322 | ||
| Perceived stress (PSS-10) | 0.321 | 0.046 | 0.208 | 7.035 | <0.001 | 0.231 | 0.411 | |||
| Social support (MSPSS) | −0.137 | 0.016 | −0.394 | −8.351 | <0.001 | 0.701 | 0.47 *** | −0.169 | −0.105 | |
| Alcohol dependence (AUDIT) | 0.246 | 0.032 | 0.371 | 7.748 | <0.001 | 0.701 | 0.47 *** | 0.184 | 0.308 | |
| Block 4 | Gender | −0.238 | 0.305 | −0.022 | −0.779 | 0.436 | −0.828 | 0.371 | ||
| Perceived stress (PSS-10) | 0.322 | 0.046 | 0.209 | 7.042 | <0.001 | 0.233 | 0.413 | |||
| Social support (MSPSS) | −0.127 | 0.017 | −0.364 | −7.503 | <0.001 | −0.160 | −0.093 | |||
| Alcohol dependence (AUDIT) | 0.205 | 0.036 | 0.308 | 5.655 | <0.001 | 0.134 | 0.276 | |||
| Nicotine dependence (FTND) | 0.157 | 0.079 | 0.092 | 1.973 | 0.049 * | 0.001 | 0.313 | |||
| Physical activity (IPAQ) | −0.659 | 0.295 | −0.069 | −2.239 | 0.026 * | 0.705 | 0.004 * | −1.239 | −0.080 |
| Type | Model Variables | B | SE(B) | Lower 95% CI | Upper 95% CI | β | z | p |
|---|---|---|---|---|---|---|---|---|
| Indirect | PSS-10 ⇒ MSPSS ⇒ GAD-7 | 0.387 | 0.0525 | 0.284 | 0.490 | 0.251 | 7.37 | <0.001 |
| Component | PSS-10 ⇒ MSPSS | −1.609 | 0.2058 | −2.013 | −1.206 | −0.362 | −7.82 | <0.001 |
| MSPSS ⇒ GAD-7 | −0.240 | 0.0109 | −0.262 | −0.219 | −0.692 | −21.99 | <0.001 | |
| Direct | PSS-10 ⇒ GAD-7 | 0.364 | 0.0486 | 0.268 | 0.459 | 0.236 | 7.49 | <0.001 |
| Total | PSS-10 ⇒ GAD-7 | 0.751 | 0.0671 | 0.619 | 0.882 | 0.486 | 11.18 | <0.001 |
| Model Variables | β | t | p | R2 | ΔR2 | Lower 95% CI | Upper 95% CI | |
|---|---|---|---|---|---|---|---|---|
| Block 1 | Perceived stress (PSS10) | 0.463 | 11.704 | <0.001 | 0.594 | 0.834 | ||
| Physical activity (IPAQ) | −0.373 | −9.432 | <0.001 | 0.375 | 0.138 *** | −4.302 | −2.818 | |
| Block: 2 | Perceived stress (PSS10) | 0.464 | 11.873 | <0.001 | 0.598 | 0.835 | ||
| Physical activity (IPAQ) | −0.372 | −9.531 | <0.001 | −4.291 | −2.824 | |||
| Interaction Z_Physical activity × Z_Perceived stress | −0.124 | −3.171 | 0.002 | 0.390 | 0.015 ** | −0.208 | −0.888 | |
| Block 1 | Perceived stress (PSS10) | 0.288 | 9.238 | <0.001 | 0.350 | 0.540 | ||
| Alcohol dependence (AUDIT) | 0.668 | 21.420 | <0.001 | 0.643 | 0.076 *** | 3.831 | 4.605 | |
| Block 2 | Perceived stress (PSS10) | 0.287 | 9.273 | <0.001 | 0.350 | 0.540 | ||
| Alcohol dependence (AUDIT) | 0.682 | 21.637 | <0.001 | 3.912 | 4.694 | |||
| Interaction Z_Alcohol dependence (AUDIT) × Z_Perceived stress | 0.073 | 2.422 | 0.016 | 0.648 | 0.005 * | 0.071 | 0.686 | |
| Block 1 | Perceived stress (PSS10) | 0.303 | 8.400 | <0.001 | 0.358 | 0.577 | ||
| Nicotine dependence (FTND) | 0.573 | 15.896 | <0.001 | 0.531 | 0.082 *** | 2.634 | 3.378 | |
| Block 2 | Perceived stress (PSS10) | 0.279 | 7.694 | <0.001 | 0.321 | 0.541 | ||
| Nicotine dependence (FTND) | 0.607 | 16,420 | <0.001 | 2.802 | 3.565 | |||
| Interaction Z_Nicotine dependence (FTND) × Z_Perceived stress | 0.119 | 3.390 | <0.001 | 0.544 | 0.013 ** | 0.088 | 0.330 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Malinauskiene, V.; Malinauskas, R. Relationship Between Perceived Stress and Anxiety in High School Senior Students: The Mediating Role of Social Support and the Moderating Influence of Lifestyle. Healthcare 2026, 14, 263. https://doi.org/10.3390/healthcare14020263
Malinauskiene V, Malinauskas R. Relationship Between Perceived Stress and Anxiety in High School Senior Students: The Mediating Role of Social Support and the Moderating Influence of Lifestyle. Healthcare. 2026; 14(2):263. https://doi.org/10.3390/healthcare14020263
Chicago/Turabian StyleMalinauskiene, Vilija, and Romualdas Malinauskas. 2026. "Relationship Between Perceived Stress and Anxiety in High School Senior Students: The Mediating Role of Social Support and the Moderating Influence of Lifestyle" Healthcare 14, no. 2: 263. https://doi.org/10.3390/healthcare14020263
APA StyleMalinauskiene, V., & Malinauskas, R. (2026). Relationship Between Perceived Stress and Anxiety in High School Senior Students: The Mediating Role of Social Support and the Moderating Influence of Lifestyle. Healthcare, 14(2), 263. https://doi.org/10.3390/healthcare14020263

