Prevalence of Stroke in Spain and Its Impact on Quality of Life: Socioeconomic Inequalities and Access to Rehabilitation
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Physical Activity
Specialist Contacts and Limitations
4. Discussion
Limitations of the Study
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Grau García, M.; Pérez Bea, M.; Angulo Saiz, A.; Díez Fontaneda, V.; Cintora Leon, E. Actualización del código ictus en urgencias. Radiologia. Soc. Española Radiol. Médica 2023, 65, S3–S10. [Google Scholar] [CrossRef]
- Majumder, D. Ischemic Stroke: Pathophysiology and Evolving Treatment Approaches. In Neuroscience Insights; SAGE Publications Ltd.: Thousand Oaks, CA, USA, 2024; Volume 19. [Google Scholar] [CrossRef]
- Chen, J.; Zeng, Z.; Fang, Z.; Ma, F.; Lv, M.; Zhang, J. Risk factors for thrombolysis-related intracranial hemorrhage: A systematic review and meta-analysis. Thromb. J. 2023, 21, 1–8. [Google Scholar] [CrossRef] [PubMed]
- Ministerio de Sanidad. Ministerio de Sanidad y Comunidades Autónomas Aprueban la Actualización de la Estrategia del Ictus. 14 February 2023. Available online: https://www.sanidad.gob.es/gabinete/notasPrensa.do?id=6395 (accessed on 15 October 2024).
- Feigin, V.L.; Abate, M.D.; Abate, Y.H.; Abd ElHafeez, S.; Abd-Allah, F.; Abdelalim, A.; Abdelkader, A.; Abdelmasseh, M.; Abd-Elsalam, S.; Abdi, P.; et al. Global, regional, and national burden of stroke and its risk factors, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021. Lancet Neurol. 2024, 23, 973–1003. [Google Scholar] [CrossRef] [PubMed]
- Soto, A.; Guillén-Grima, F.; Morales, G.; Muñoz, S.; Aguinaga-Ontoso, I.; Fuentes-Aspe, R. Prevalence and incidence of ictus in Europe: Systematic review and meta-analysis. An. Del Sist. Sanit. Navar. 2022, 45, e0979. [Google Scholar] [CrossRef] [PubMed]
- Lopez, A.D.; Adair, T. Is the long-term decline in cardiovascular-disease mortality in high-income countries over? Evidence from national vital statistics. Int. J. Epidemiol. 2019, 48, 1815–1823. [Google Scholar] [CrossRef]
- Höhn, A.; Gampe, J.; Lindahl-Jacobsen, R.; Christensen, K.; Oksuyzan, A. Do men avoid seeking medical advice? A register-based analysis of gender-specific changes in primary healthcare use after first hospitalisation at ages 60+ in Denmark. J. Epidemiol. Community Health 2020, 74, 573–579. [Google Scholar] [CrossRef]
- Ramírez-Moreno, J.M.; Alonso-González, R.; Pacheco, D.P.; Millán-Nuñez, M.V.; Roa-Montero, A.; Constantino-Silva, A.B.; Aguirre-Sánchez, J.J. Impacto del nivel socioeconómico en el conocimiento del ictus de la población general: Un gradiente de desigualdad social. Neurologia 2016, 31, 24–32. [Google Scholar] [CrossRef]
- Madsen, T.E.; Samaei, M.; Pikula, A.; Yu, A.Y.; Carcel, C.; Millsaps, E.; Yalamanchili, R.S.; Bencie, N.; Dula, A.N.; Leppert, M.; et al. Sex Differences in Physical Activity and Incident Stroke: A Systematic Review. Clin. Ther. 2022, 44, 586–611. [Google Scholar] [CrossRef]
- Ogwumike, O.O.; Omoregie, A.A.; Dada, O.O.; Badaru, U.M. Quality of life of stroke survivors: A cross-sectional study of associa-tion with functional independence, self-reported fatigue and exercise self-efficacy. Chronic Illn. 2022, 18, 599–607. [Google Scholar] [CrossRef]
- Shi, Y.; Howe, T.H.; Halpin, P.F.; Hu, L.; Wu, B. Dyadic analysis of illness perceptions among individuals with stroke and their caregivers: Effects on activity engagement in community living. Disabil. Rehabil. 2024, 46, 3342–3354. [Google Scholar] [CrossRef]
- Egido, J.A.; Alonso De Leciñana, M. Peculiarities of stroke risk in women. Cerebrovasc. Dis. 2007, 24, 76–83. [Google Scholar] [CrossRef] [PubMed]
- Martino Cinnera, A.; Bonnì, S.; Pellicciari, M.C.; Giorgi, F.; Caltagirone, C.; Koch, G. Health-related quality of life (HRQoL) after stroke: Positive relationship between lower extremity and balance recovery. Top Stroke Rehabil. 2020, 27, 534–540. [Google Scholar] [CrossRef] [PubMed]
- Kaindl, L.; Hotz, J.F.; Ferrari, J. Cutting-edge stroke prevention strategies. eNeurologicalSci 2025, 39, 100561. [Google Scholar] [CrossRef] [PubMed]
- Kusec, A.; Milosevich, E.; Williams, O.A.; Chiu, E.G.; Watson, P.; Carrick, C.; Drozdowska, B.A.; Dillon, A.; Jennings, T.; Anderson, B.; et al. Long-term psychological outcomes following stroke: The OX-CHRONIC study. BMC Neurol. 2023, 23, 1–17. [Google Scholar] [CrossRef]
- Lucas-Noll, J.; Clua-Espuny, J.L.; Lleixà-Fortuño, M.; Gavaldà-Espelta, E.; Queralt-Tomas, L.; Panisello-Tafalla, A.; Carles-Lavila, M. The costs associated with stroke care continuum: A systematic review. Health Econ. Rev. 2023, 13, 1–18. [Google Scholar] [CrossRef]
- Tramontano, M.; Argento, O.; Manocchio, N.; Piacentini, C.; Orejel Bustos, A.S.; De Angelis, S.; Bossa, M.; Nocentini, U. Dynamic Cognitive–Motor Training versus Cognitive Computer-Based Training in People with Multiple Sclerosis: A Preliminary Randomized Controlled Trial with 2-Month Follow-Up. J. Clin. Med. 2024, 13, 2664. [Google Scholar] [CrossRef]
- Bossa, M.; Manocchio, N.; Argento, O. Non-Pharmacological Treatments of Cognitive Impairment in Multiple Sclerosis: A Review. NeuroSci 2022, 3, 476–493. [Google Scholar] [CrossRef]
- Regulation-141/2013-EN-EUR-Lex. Available online: https://eur-lex.europa.eu/eli/reg/2013/141/oj (accessed on 2 November 2024).
- EUROSTAT. European Health Interview Survey-Microdata-Eurostat. EUROSTAT. 2020. Available online: https://ec.europa.eu/eurostat/web/microdata/european-health-interview-survey (accessed on 2 November 2024).
- López Espuela, F.; Portilla Cuenca, J.C.; Leno Díaz, C.; Párraga Sánchez, J.M.; Gamez-Leyva, G.; Casado Naranjo, I. Diferencias de género en la calidad de vida a largo plazo tras un ictus: Influencia del estado funcional y el estado de ánimo. Neurología 2020, 35, 470–478. [Google Scholar] [CrossRef]
- Teuschl, Y.; Brainin, M. Stroke education: Discrepancies among factors influencing prehospital delay and stroke knowledge. Int. J. Stroke 2010, 5, 187–208. [Google Scholar] [CrossRef]
- Kowalczyk, B.; Zawadzka, B. Lifestyle and Quality of Life in Working-Age People after Stroke. Acta Clin. Croat. 2020, 59, 30–36. [Google Scholar] [CrossRef]
- Heredia, N.M.; Rodríguez, E.S.; Rodríguez-García, A.M. Beneficios de la actividad física para la promoción de un envejecimiento activo en personas mayores. Revisión bibliográfica. Retos 2021, 39, 829–834. [Google Scholar] [CrossRef]
- Panagiotou, M.; Michel, S.; Meijer, J.H.; Deboer, T. The aging brain: Sleep, the circadian clock and exercise. Biochem. Pharmacol. 2021, 191, 114563. [Google Scholar] [CrossRef] [PubMed]
- Aguiar, L.T.; Nadeau, S.; Britto, R.R.; Teixeira-Salmela, L.F.; Martins, J.C.; Samora, G.A.; da Silva Junior, J.A.; Faria, C.D. Effects of aerobic training on physical activity in people with stroke: A randomized controlled trial. NeuroRehabilitation 2020, 46, 391–401. [Google Scholar] [CrossRef] [PubMed]
- Serra, M.C.; Accardi, C.J.; Ma, C.; Park, Y.; Tran, V.; Jones, D.P.; Hafer-Macko, C.E.; Ryan, A.S. Metabolomics of Aerobic Exercise in Chronic Stroke Survivors: A Pilot Study. J. Stroke Cerebrovasc. Dis. 2019, 28, 104453. [Google Scholar] [CrossRef]
- Vyas, M.V.; Silver, F.L.; Austin, P.C.; Yu, A.Y.; Pequeno, P.; Fang, J.; Laupacis, A.; Kapral, M.K. Stroke Incidence by Sex Across the Lifespan. Stroke 2021, 52, 447–451. [Google Scholar] [CrossRef]
- Li, H.; Pin, S.; Zeng, Z.; Wang, M.M.; Andreasson, K.A.; McCullough, L.D. Sex differences in cell death. Ann. Neurol. 2005, 58, 317–321. [Google Scholar] [CrossRef]
- Howard, V.J.; Lackland, D.T.; Lichtman, J.H.; McClure, L.A.; Howard, G.; Wagner, L.; Pulley, L.; Gomez, C.R. Care seeking after stroke symptoms. Ann. Neurol. 2008, 63, 466–472. [Google Scholar] [CrossRef]
Men n (%) | Women n (%) | p-Value | ||
---|---|---|---|---|
Level of education | No studies or Incomplete Primary Education | 34 (30.4) | 78 (59.6) | <0.001 |
Primary education | 68 (47.9) | 74 (52.1) | ||
Secondary education | 70 (49.7) | 71 (51.3) | ||
University studies | 34 (68.0) | 16 (32.0) | ||
Cohabitation | With spouse/domestic partner | 136 (61.6) | 84 (38.4) | <0.001 |
Not living together as a couple | 70 (31.1) | 155 (68.9) | ||
Current or Past Occupation | Direction/management > 10 employees | 17 (58.6) | 12 (41.4) | 0.356 |
Direction/management < 10 employees | 14 (50.0) | 14 (50.0) | ||
Intermediate occupations and self-employed | 31 (43.7) | 40 (56.3) | ||
Supervisors and workers in technical occupations | 40 (51.3) | 38 (48.7) | ||
Skilled workers in the primary sector and others | 81 (50.6) | 79 (49.4) | ||
Unskilled workers | 21 (36.8) | 36 (63.2) | ||
Health status in the last 12 months | Very good | 4 (36.4) | 7 (63.6) | 0.025 |
Good | 57 (60.6) | 37 (39.4) | ||
Fair | 77 (43.8) | 99 (56.3) | ||
Bad | 54 (43.5) | 70 (56.5) | ||
Very bad | 14 (35.0) | 26 (65.0) | ||
Have a chronic disease or health problem | Yes | 198 (45.8) | 234 (54.2) | 0.263 |
No | 8 (61.5) | 5 (38.5) | ||
Limitations on carrying out activities | Severely limited | 56 (42.1) | 77 (57.9) | 0.021 |
Limited, but not severely | 86 (42.8) | 115 (57.2) | ||
Nothing limited | 64 (57.7) | 47 (42.3) | ||
Type of problem causing the limitations in performing activities | Physics | 109 (43.8) | 140 (56.2) | 0.716 |
Mental | 4 (36.4) | 7 (63.6) | ||
Both | 29 (39.2) | 45 (60.8) | ||
Difficulty walking 500 m on flat ground without any help | No difficulty | 119 (58.6) | 84 (41.4) | <0.001 |
Some difficulty | 37 (35.9) | 66 (64.1) | ||
A lot of difficulty | 26 (32.1) | 55 (67.9) | ||
I cannot do it at all | 24 (41.4) | 34 (58.6) | ||
Difficulty going up or down 12 steps | No difficulty | 106 (63.1) | 62 (38.9) | <0.001 |
Some difficulty | 43 (41.3) | 61 (58.7) | ||
A lot of difficulty | 31 (30.7) | 70 (69.3) | ||
I cannot do it at all | 26 (36.1) | 46 (63.9) | ||
Difficulty remembering or concentrating | No difficulty | 118 (52.9) | 105 (47.1) | 0.008 |
Some difficulty | 54 (40.9) | 78 (59.1) | ||
A lot of difficulty | 30 (43.5) | 39 (56.5) | ||
I cannot do it at all | 4 (19.0) | 17 (81.0) |
Men | Women | p-Value | ||
---|---|---|---|---|
Main activity in the workplace, school, home (housework)… | Sitting most of the day | 118 (44.7) | 146 (55.3) | 0.956 |
Standing most of the day without making large movements or efforts | 46 (46.5) | 53 (53.5) | ||
Walking, carrying some weight, making frequent movements | 11 (50.0) | 11 (50.0) | ||
Performing tasks that require great physical effort | 2 (50.0) | 2 (50.0) | ||
How often do you do any physical activity in your free time? | I do not exercise. I occupy my free time in an almost completely sedentary way (reading, watching television, going to the movies, etc.). | 107 (42.0) | 148 (58.0) | 0.189 |
I do some occasional physical or sports activity (walking or cycling, gardening, gentle gymnastics, recreational activities that require a light effort, etc.) | 74 (51.7) | 69 (48.3) | ||
I do physical activity several times a month (sports, gymnastics, running, swimming, cycling, team games, etc.) | 13 (50.0) | 13 (50.0) | ||
I do sports or physical training several times a week | 12 (57.1) | 9 (42.9) | ||
In a week of normal activity, how many days do you walk at least 10 min at a time to get around? * | 4.21 (3.0) | 3.05 (3.01) | <0.001 | |
Usually, on one of those days, how long do you walk to get around? | 10 to 29 min | 81 (48.5) | 86 (51.5) | 0.095 |
30 to 59 min | 47 (61.0) | 30 (39.0) | ||
One hour or more but less than two hours | 16 (50.0) | 16 (50.0) | ||
Two hours or more but less than three hours | 4 (100) | 0 (0) | ||
Three hours or more | 1 (100) | 0 (0) | ||
In your leisure time during a normal activity week, how many days do you play sports, gymnastics, cycling, brisk walking, etc., at least 10 min at a time? * | 1.31 (2.37) | 1.19 (2.27) | 0.303 | |
In your leisure time during a normal activity week, how many days do you do activities specifically aimed at strengthening your muscles? * | 0.39 (1.37) | 0.3 (1.28) | 0.233 | |
How long (hours) do you sit on a typical day? * | 9.09 (14.68) | 10.98 (18.69) | 0.121 |
Men | Women | p-Value | |||
---|---|---|---|---|---|
Difficulty doing activities without help | Feed | No difficulty | 162 (47.4) | 180 (52.6) | 0.351 |
Some difficulty | 10 (31.3) | 22 (68.8) | |||
A lot of difficulty | 7 (46.7) | 8 (53.3) | |||
I cannot do it by myself | 6 (40.0) | 9 (60.0) | |||
Sitting, getting up from a chair or bed, lying down | No difficulty | 145 (53.9) | 124 (46.1) | <0.001 | |
Some difficulty | 15 (24.2) | 47 (75.8) | |||
A lot of difficulty | 12 (30.0) | 28 (70.0) | |||
I cannot do it by myself | 13 (39.4) | 20 (60.6) | |||
Dressing and undressing | No difficulty | 144 (53.7) | 124 (46.3) | <0.001 | |
Some difficulty | 14 (25.5) | 41 (74.5) | |||
A lot of difficulty | 11 (30.6) | 25 (69.4) | |||
I cannot do it by myself | 16 (35.6) | 29 (64.4) | |||
Go to service | No difficulty | 149 (50.5) | 146 (49.5) | 0.009 | |
Some difficulty | 12 (28.6) | 30 (71.4) | |||
A lot of difficulty | 8 (28.6) | 20 (71.4) | |||
I cannot do it by myself | 16 (41.0) | 23 (59.0) | |||
Showering or bathing | No difficulty | 133 (56.6) | 102 (43.4) | <0.001 | |
Some difficulty | 22 (32.4) | 46 (67.6) | |||
A lot of difficulty | 8 (21.1) | 30 (78.9) | |||
I cannot do it by myself | 22 (34.9) | 41 (65.1) | |||
Difficulty doing on their own and without help | Preparing meals | No difficulty | 116 (49.8) | 117 (50.2) | <0.001 |
Some difficulty | 8 (21.6) | 29 (78.4) | |||
A lot of difficulty | 3 (16.7) | 15 (83.3) | |||
I cannot do it by myself | 26 (33.3) | 52 (66.7) | |||
Use the phone (look up numbers, dial, …) | No difficulty | 147 (51.2) | 140 (4.8) | 0.005 | |
Some difficulty | 8 (29.6) | 19 (70.4) | |||
A lot of difficulty | 7 (30.4) | 16 (69.6) | |||
I cannot do it by myself | 18 (31.6) | 39 (68.4) | |||
Make purchases (food, clothes, …) | No difficulty | 119 (56.7) | 91 (43.3) | <0.001 | |
Some difficulty | 15 (39.5) | 23 (60.5) | |||
A lot of difficulty | 7 (18.4) | 31(81.6) | |||
I cannot do it by myself | 31 (31.6) | 67 (68.4) | |||
Taking your medicines, including remembering how much and when to take them | No difficulty | 148 (53.8) | 127 (46.2) | <0.001 | |
Some difficulty | 14 (35.0) | 26 (65.0) | |||
A lot of difficulty | 1 (4.5) | 21 (95.5) | |||
I cannot do it by myself | 21 (34.4) | 40 (65.6) | |||
Perform light household chores (doing laundry, making the bed, cleaning the house, …) | No difficulty | 101 (55.5) | 81 (44.5) | <0.001 | |
Some difficulty | 15 (32.6) | 31 (67.4) | |||
A lot of difficulty | 10 (20.4) | 39 (79.6) | |||
I cannot do it by myself | 31 (33.0) | 63 (67.0) | |||
Occasionally performing household chores that require a great deal of effort (moving furniture, cleaning windows, …) | No difficulty | 78 (66.7) | 39 (33.3) | <0.001 | |
Some difficulty | 18 (39.1) | 28 (60.9) | |||
A lot of difficulty | 20 (40.0) | 30 (60.0) | |||
I cannot do it by myself | 40 (26.3) | 112 (73.7) | |||
Manage your own money (pay bills, deal with the bank, …) | No difficulty | 141 (53.2) | 124 (46.8) | <0.001 | |
Some difficulty | 11 (33.3) | 22 (66.7) | |||
A lot of difficulty | 6 (26.1) | 17 (73.9) | |||
I cannot do it by myself | 21 (29.2) | 51 (70.8) |
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García-Campanario, I.; Vinolo-Gil, M.J. Prevalence of Stroke in Spain and Its Impact on Quality of Life: Socioeconomic Inequalities and Access to Rehabilitation. Healthcare 2025, 13, 1075. https://doi.org/10.3390/healthcare13091075
García-Campanario I, Vinolo-Gil MJ. Prevalence of Stroke in Spain and Its Impact on Quality of Life: Socioeconomic Inequalities and Access to Rehabilitation. Healthcare. 2025; 13(9):1075. https://doi.org/10.3390/healthcare13091075
Chicago/Turabian StyleGarcía-Campanario, Ismael, and Maria Jesus Vinolo-Gil. 2025. "Prevalence of Stroke in Spain and Its Impact on Quality of Life: Socioeconomic Inequalities and Access to Rehabilitation" Healthcare 13, no. 9: 1075. https://doi.org/10.3390/healthcare13091075
APA StyleGarcía-Campanario, I., & Vinolo-Gil, M. J. (2025). Prevalence of Stroke in Spain and Its Impact on Quality of Life: Socioeconomic Inequalities and Access to Rehabilitation. Healthcare, 13(9), 1075. https://doi.org/10.3390/healthcare13091075