Shared and Unique Proteins in Human, Mouse and Rat Saliva Proteomes: Footprints of Functional Adaptation
- Which proteins are shared between the two human saliva proteomes and which are not?
- Does a deeper proteome necessarily improve the protein representation of salivary gland secretions?
- Does using saliva collected from individual salivary gland ducts, rather than whole saliva, improve the representation of salivary gland secretions in the final analysis?
- What proteins are shared by the human, mouse and rat saliva proteomes, and which are shared by two of the three proteomes?
- Are the proteins shared between two or all three mammal proteomes encoded by genes with known evolutionary relationships, that is to say that they are orthologous or paralogous; or is their apparent similarity an accident of naming that does not represent a true evolutionary relationship?
- What proteins are unique to the saliva proteomes of each of the three mammals?
2.1. Protein Identification from Proteomic Data
2.3. Identifying Secreted and Non-Secreted Proteins in the Saliva Proteomes
2.4. Identifying Similar Proteins
3. Results and Discussion
3.1. Comparing and Contrasting the Proteins Identified in Two Human Saliva Proteomes
3.4. Proteins Unique to Rodent Saliva
3.5. Proteins Unique to Each Saliva Proteome
Supplementary MaterialsSupplementary File 1
Conflicts of Interest
- SF2: Human salivary proteins unique to  with signal peptides, listing shared expression;
- SF3: Human salivary proteins unique to  with SignalP and shared expression status;
- SF4: Mouse salivary proteins  with SignalP and shared expression status;
- SF5: Rat salivary proteins  with SignalP and shared expression status.
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Karn, R.C.; Chung, A.G.; Laukaitis, C.M. Shared and Unique Proteins in Human, Mouse and Rat Saliva Proteomes: Footprints of Functional Adaptation. Proteomes 2013, 1, 275-289. https://doi.org/10.3390/proteomes1030275
Karn RC, Chung AG, Laukaitis CM. Shared and Unique Proteins in Human, Mouse and Rat Saliva Proteomes: Footprints of Functional Adaptation. Proteomes. 2013; 1(3):275-289. https://doi.org/10.3390/proteomes1030275Chicago/Turabian Style
Karn, Robert C., Amanda G. Chung, and Christina M. Laukaitis. 2013. "Shared and Unique Proteins in Human, Mouse and Rat Saliva Proteomes: Footprints of Functional Adaptation" Proteomes 1, no. 3: 275-289. https://doi.org/10.3390/proteomes1030275