Generative AI and Cognitive Challenges in Research: Balancing Cognitive Load, Fatigue, and Human Resilience
Abstract
1. Introduction
2. Literature Review
2.1. Cognitive Load
2.2. Task Fatigue and Mental Exhaustion
2.3. Research Engagement
2.4. Resilience to Cognitive Fatigue
2.5. Research Production and Efficiency
2.6. Generative AI and Research Productivity and Efficiency
3. Methodology
3.1. Research Design
3.2. Theoretical Foundation
3.3. Constructs and Measurement Model
3.4. Sample and Data Collection
3.5. Data Analysis Procedure
3.6. Moderation and Mediation Strategy
3.7. Ethical Considerations
4. Data Analysis and Interpretation
4.1. Measurement Model
4.2. Structural Model
5. Discussion
Concise Summary of Results
6. Conclusions
6.1. Future Avenues of Research
Limitations of the Study
6.2. Implications of the Study
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Appendix A
| Relationship | f-Square |
|---|---|
| Cognitive Load → Research Engagement | 1.017 |
| Cognitive Load → Research Quality & Academic Influence | 0.043 |
| Cognitive Load → Resilience to Cognitive Fatigue | 0.021 |
| Generative AI → Research Quality & Academic Influence | 2.5 |
| Generative AI x Cognitive Load → Research Quality & Academic Influence | 0.017 |
| Generative AI x Task Fatigue & Mental Exhaustion → Research Quality & Academic Influence | 0.057 |
| Research Engagement → Research Quality & Academic Influence | 0.049 |
| Resilience to Cognitive Fatigue → Research Engagement | 0.001 |
| Resilience to Cognitive Fatigue → Research Quality & Academic Influence | 0.038 |
| Task Fatigue & Mental Exhaustion → Research Engagement | 0.003 |
| Task Fatigue & Mental Exhaustion → Research Quality & Academic Influence | 0.026 |
| Task Fatigue & Mental Exhaustion → Resilience to Cognitive Fatigue | 0.955 |
Appendix B
| Pathway | Effect Size (f2) | Gap Identified |
|---|---|---|
| Cognitive Load → Engagement | 1.017 (Very Large) | Investigate optimal cognitive stimulation levels and task design per field/discipline. |
| GenAI → Research Quality | 2.5 (Very Large) | Explore how task-AI alignment or user training impacts responsible GenAI usage. |
| Task Fatigue → Resilience | 0.955 (Very Large) | Develop resilience-building interventions tailored for high-stakes research roles. |
| Engagement → Research Quality | 0.049 (Moderate) | Decompose engagement into cognitive, emotional, and behavioral dimensions. |
| Task Fatigue → Engagement | 0.003 (Negligible) | Explore alternative mediators (e.g., emotional regulation, digital breaks). |
| Cognitive Load → Research Quality | 0.043 (Small) | Understand why some high-load tasks still yield high research outcomes (e.g., flow states). |
Appendix C
| Items | Code | Research Quality & Academic Influence | MV Performance |
|---|---|---|---|
| I often feel mentally overloaded when managing multiple research activities. | CL1 | −0.009 | 38.339 |
| The complexity of my research tasks makes it hard to concentrate. | CL2 | −0.009 | 38.566 |
| I find it mentally challenging to organize and analyze large volumes of information. | CL3 | −0.009 | 38.203 |
| I regularly use tools like ChatGPT or Elicit for literature review and writing support. | Gen AI1 | −0.236 | 39.156 |
| Generative AI helps me simplify complex tasks during my research. | Gen AI2 | −0.229 | 38.294 |
| I rely heavily on AI tools to assist in data analysis or content generation. | Gen AI3 | −0.238 | 38.838 |
| AI integration has become a central part of my research workflow. | Gen AI4 | −0.232 | 38.385 |
| Even when I feel mentally tired, I can still focus on research tasks. | RCF1 | 0.056 | 38.612 |
| I am able to bounce back quickly after mentally exhausting research work. | RCF2 | 0.058 | 51.664 |
| I can stay productive in research even under prolonged mental strain. | RCF3 | 0.057 | 37.432 |
| I feel deeply involved and interested in my research activities. | RE1 | 0.069 | 38.884 |
| I am enthusiastic and motivated about conducting research. | RE2 | 0.069 | 38.475 |
| I feel mentally energized when working on research projects. | RE3 | 0.07 | 38.884 |
| I feel mentally exhausted after prolonged research work. | TFME1 | −0.002 | 39.247 |
| I find it difficult to stay focused when working on research for extended hours. | TFME2 | −0.002 | 39.065 |
| Even small research tasks feel overwhelming when I am tired. | TFME3 | −0.002 | 52.753 |
Appendix D

Appendix E
| Education Level | Number of Respondents | Percentage (%) |
|---|---|---|
| Master’s Degree | 507 | 50.80% |
| Doctoral Degree (PhD) | 358 | 35.87% |
| Postdoctoral/Faculty | 133 | 13.33% |
| Total | 998 | 100% |
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| Construct | Code | Items | Adapted from |
|---|---|---|---|
| Cognitive Load | CL1–CL3 | 3 | [78,79] |
| Task Fatigue & Mental Exhaustion | TFME1–TFME3 | 3 | [80,81] |
| Generative AI Immersion | GenAI1–GenAI4 | 4 | Adapted from [82,83] |
| Research Engagement | RE1–RE3 | 3 | [84,85] |
| Resilience to Cognitive Fatigue | RCF1–RCF3 | 3 | [86] |
| Research Quality & Academic Influence | RQAI1–RQAI8 | 8 | [58,87] |
| Constructs | Cronbach’s Alpha | Composite Reliability (rho_a) | Composite Reliability (rho_c) | Average Variance Extracted (AVE) |
|---|---|---|---|---|
| Cognitive Load | 0.886 | 0.886 | 0.929 | 0.814 |
| Generative AI | 0.915 | 0.915 | 0.940 | 0.796 |
| Research Engagement | 0.897 | 0.897 | 0.936 | 0.829 |
| Research Quality & Academic Influence | 0.912 | 0.913 | 0.929 | 0.620 |
| Resilience to Cognitive Fatigue | 0.883 | 0.883 | 0.928 | 0.810 |
| Task Fatigue & Mental Exhaustion | 0.895 | 0.896 | 0.935 | 0.826 |
| Constructs | Cognitive Load | Generative AI | Research Engagement | Research Quality & Academic Influence | Resilience to Cognitive Fatigue | Task Fatigue & Mental Exhaustion | Generative AI x Task Fatigue & Mental Exhaustion | Generative AI x Cognitive Load |
|---|---|---|---|---|---|---|---|---|
| Cognitive Load | ||||||||
| Generative AI | 0.021 | |||||||
| Research Engagement | 0.805 | 0.018 | ||||||
| Research Quality & Academic Influence | 0.049 | 0.883 | 0.085 | |||||
| Resilience to Cognitive Fatigue | 0.048 | 0.046 | 0.095 | 0.055 | ||||
| Task Fatigue & Mental Exhaustion | 0.079 | 0.039 | 0.047 | 0.080 | 0.765 | |||
| Generative AI x Task Fatigue & Mental Exhaustion | 0.026 | 0.064 | 0.023 | 0.104 | 0.040 | 0.026 | ||
| Generative AI x Cognitive Load | 0.055 | 0.045 | 0.029 | 0.101 | 0.023 | 0.041 | 0.078 |
| Constructs | R-Square | R-Square Adjusted | Q2 Predict | RMSE | MAE |
|---|---|---|---|---|---|
| Research Engagement | 0.521 | 0.519 | 0.516 | 0.698 | 0.417 |
| Research Quality & Academic Influence | 0.709 | 0.707 | 0.674 | 0.573 | 0.344 |
| Resilience to Cognitive Fatigue | 0.472 | 0.471 | 0.468 | 0.732 | 0.439 |
| Model Fit | Saturated model | Estimated model | |||
| SRMR | 0.054 | 0.057 | |||
| d_ULS | 0.884 | 0.99 | |||
| d_G | 0.427 | 0.425 | |||
| Chi-square | 2824.476 | 2850.245 | |||
| NFI | 0.845 | 0.843 |
| Hypothesis | Path | Original Sample (O) | Sample Mean (M) | Standard Deviation (STDEV) | T Statistics (|O/STDEV|) | p Values | f Square |
|---|---|---|---|---|---|---|---|
| H1 | Cognitive Load → Research Quality & Academic Influence | −0.175 | −0.175 | 0.033 | 5.371 | 0.000 | 0.049 |
| H2 | Task Fatigue & Mental Exhaustion → Research Quality & Academic Influence | −0.124 | −0.124 | 0.033 | 3.722 | 0.000 | 0.027 |
| H3 | Generative AI Immersion x Cognitive Load → Research Quality & Academic Influence | −0.067 | −0.067 | 0.017 | 3.966 | 0.000 | 0.025 |
| H4 | Generative AI Immersion x Task Fatigue & Mental Exhaustion → Research Quality & Academic Influence | −0.114 | −0.113 | 0.018 | 6.261 | 0.000 | 0.082 |
| H5 | Cognitive Load → Research Engagement → Research Quality & Academic Influence | 0.137 | 0.138 | 0.025 | 5.5 | 0.000 | |
| H6 | Cognitive Load → Resilience to Cognitive Fatigue → Research Quality & Academic Influence | 0.014 | 0.014 | 0.006 | 2.398 | 0.017 | |
| H7 | Task Fatigue & Mental Exhaustion → Research Engagement → Research Quality & Academic Influence | 0.012 | 0.012 | 0.008 | 1.544 | 0.123 | |
| H8 | Task Fatigue & Mental Exhaustion → Resilience to Cognitive Fatigue → Research Quality & Academic Influence | 0.104 | 0.104 | 0.022 | 4.647 | 0.000 |
| Objective | Gap Identified | Suggested Research Direction | Relevance |
|---|---|---|---|
| Understand when GenAI is helpful vs. harmful | Current evidence shows over-reliance on GenAI can reduce research quality, but the “tipping point” is unclear. | Conduct longitudinal studies to identify threshold levels of GenAI use where benefits turn into drawbacks. | Advances knowledge on AI adoption and sustainable technology use. |
| Explore the interaction between human traits and AI | Resilience and engagement buffer cognitive strain, but their role in AI-rich environments is not fully understood. | Study how resilience, motivation, and engagement evolve in long-term AI-supported research settings. | Connects with assistive and educational technologies that strengthen human performance. |
| Design adaptive AI systems | Current GenAI tools are static and not context-aware; they do not adjust to user fatigue or cognitive load. | Develop AI systems that detect user strain and provide adaptive support to maintain well-being and creativity. | Aligns with AI innovation and human–technology interaction. |
| Ensure ethical and balanced AI use | Institutions lack clear rules on critical thinking, originality, and safe use of AI tools. | Investigate policy frameworks and AI literacy programs that balance efficiency with integrity. | Fits the scope of responsible and ethical technology integration. |
| Foster curiosity and engagement with AI tools | It is unclear whether AI makes researchers more curious or reduces curiosity by automating thinking. | Study how AI design features (e.g., interactivity, gamification) affect engagement and creativity. | Supports the development of human-centered ICT and educational technologies. |
| Dimension | Implication | Relevance |
|---|---|---|
| Technological | GenAI tools should be designed as assistive and adaptive systems that support, rather than replace, human cognition. Over-reliance risks lowering originality and critical thinking. | Focus on AI and ICT innovation, ensuring technology enhances human performance and creativity. |
| Human-Centered | Engagement, resilience, and intrinsic motivation remain essential for research success, even in AI-supported environments. | Aligns to advance assistive and educational technologies that strengthen human capacity. |
| Institutional | Universities and research institutions should invest in AI literacy programs, ethical guidelines, and policies that promote balanced use of AI. | Emphasis on sustainable, ethical adoption of emerging technologies. |
| Policy & Governance | Clear frameworks are needed to define thresholds where AI use shifts from helpful to harmful, protecting research integrity and originality. | Supports in shaping responsible and future-oriented technology integration. |
| Future Research | Longitudinal studies should examine how AI immersion affects resilience, fatigue, and academic outcomes over time. | Encourages contributions to the forward-looking, evidence-based technology research. |
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© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Khan, S.M.F.A.; Suhluli, S. Generative AI and Cognitive Challenges in Research: Balancing Cognitive Load, Fatigue, and Human Resilience. Technologies 2025, 13, 486. https://doi.org/10.3390/technologies13110486
Khan SMFA, Suhluli S. Generative AI and Cognitive Challenges in Research: Balancing Cognitive Load, Fatigue, and Human Resilience. Technologies. 2025; 13(11):486. https://doi.org/10.3390/technologies13110486
Chicago/Turabian StyleKhan, Syed Md Faisal Ali, and Salem Suhluli. 2025. "Generative AI and Cognitive Challenges in Research: Balancing Cognitive Load, Fatigue, and Human Resilience" Technologies 13, no. 11: 486. https://doi.org/10.3390/technologies13110486
APA StyleKhan, S. M. F. A., & Suhluli, S. (2025). Generative AI and Cognitive Challenges in Research: Balancing Cognitive Load, Fatigue, and Human Resilience. Technologies, 13(11), 486. https://doi.org/10.3390/technologies13110486

