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Article

Validation of a Novel Electronic Device for Medication Adherence Monitoring of Ambulatory Patients

Department of Pharmaceutical Sciences, Pharmaceutical Care Research Group, University of Basel, CH-4056 Basel, Switzerland
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Pharmacy 2019, 7(4), 155; https://doi.org/10.3390/pharmacy7040155
Received: 4 November 2019 / Revised: 14 November 2019 / Accepted: 15 November 2019 / Published: 20 November 2019
(This article belongs to the Section Clinical Pharmacy)
Several methods exist for measuring medication adherence. The Time4MedTM device (Adherence Innovations, Hong Kong) is a small, electronic card to affix on medication packaging that records date and time of intakes when a button is pushed. We aimed to validate the device with an emphasis on polypharmacy. Twenty volunteers used Time4MedTM devices with a virtual thrice daily intake over 14 days. Diary-recorded date and time were compared to electronically-stored events. Functionality, reliability and recovery for different stress conditions were calculated. User‘s acceptability was assessed with the System Usability Scale (SUS). Eleven elderly outpatients (mean age 80.2 ± 8.1 years) taking >3 medications daily used the device over 4 weeks. Volunteers logged 847 events. Functionality (100%), sensitivity (94.9%), specificity (99.4%) and recovery (100%) were high. Dropping the smart card and storing it in a refrigerator caused either the recording of false events or no recording at all. The mean SUS score was 82.6 (SD 14.8), demonstrating excellent acceptability. Satisfaction was very high for volunteers and patients, except for pushing the button. Time4MedTM devices are highly accurate in recording, retaining and delivering electronic data of multiple medication intake. They are well accepted by elderly patients. They can be recommended in clinical studies and for practitioners who desire to elucidate adherence patterns of ambulatory patients. View Full-Text
Keywords: medication adherence; drug labelling; Time4MedTM; smart card; polypharmacy medication adherence; drug labelling; Time4MedTM; smart card; polypharmacy
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MDPI and ACS Style

Arnet, I.; Rothen, J.-P.; Albert, V.; Hersberger, K.E. Validation of a Novel Electronic Device for Medication Adherence Monitoring of Ambulatory Patients. Pharmacy 2019, 7, 155. https://doi.org/10.3390/pharmacy7040155

AMA Style

Arnet I, Rothen J-P, Albert V, Hersberger KE. Validation of a Novel Electronic Device for Medication Adherence Monitoring of Ambulatory Patients. Pharmacy. 2019; 7(4):155. https://doi.org/10.3390/pharmacy7040155

Chicago/Turabian Style

Arnet, Isabelle, Jean-Pierre Rothen, Valerie Albert, and Kurt E. Hersberger 2019. "Validation of a Novel Electronic Device for Medication Adherence Monitoring of Ambulatory Patients" Pharmacy 7, no. 4: 155. https://doi.org/10.3390/pharmacy7040155

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