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Open AccessArticle

Melanins of Inonotus Obliquus: Bifidogenic and Antioxidant Properties

Kazan National Research Technological University, 420015 Kazan, Russian Federation, Russia
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Biomolecules 2019, 9(6), 248; https://doi.org/10.3390/biom9060248
Received: 14 May 2019 / Revised: 17 June 2019 / Accepted: 17 June 2019 / Published: 24 June 2019
Extracts and melanins from Inonotus obliquus are widely used in medicine due to their high antioxidant properties. This study is dedicated to define the influence of the physicochemical and antioxidant properties of Inonotus obliquus melanins and their bifidogenic effects on Bifidobacterium bifidum 1 and Bifidobacterium animalis subsp. lactis. For this purpose, melanins precipitated from Inonotus obliquus aqueous extracts, obtained by a few methods, and separated melanin fractions by organic solvents were used. For the melanin physicochemical properties analysis spectrophotometry, electron paramagnetic resonance (EPR) spectroscopy and dynamic light scattering methods were applied. Melanins and their fractions difference in particle size and charge, antioxidant properties, and redox potential were revealed. It was shown that the redox potential, the size of melanin particles and the z-potential had maximum influence on bifidobacteria growth. The greatest activating effect on bifidobacteria was established by using melanin isolated from aqueous microwave extracts in concentrations of 10−13, 10−10, 10−5 g/cm3. The use of this melanin with antioxidant activity 0.67 ± 0.06 mg/g (expressed as ascorbic acid equivalent), and with redox potential −5.51 ± 2.22 mV as a prebiotic allowed the growth of Bifidobacterium bifidum 1 s to increase by 1.4 times in comparison with ascorbic acid by 24 h of cultivation. View Full-Text
Keywords: melanins; Inonotus obliquus; bifidogenic; bifidobacteria; antioxidant activity melanins; Inonotus obliquus; bifidogenic; bifidobacteria; antioxidant activity
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MDPI and ACS Style

Burmasova, M.A.; Utebaeva, A.A.; Sysoeva, E.V.; Sysoeva, M.A. Melanins of Inonotus Obliquus: Bifidogenic and Antioxidant Properties. Biomolecules 2019, 9, 248.

AMA Style

Burmasova MA, Utebaeva AA, Sysoeva EV, Sysoeva MA. Melanins of Inonotus Obliquus: Bifidogenic and Antioxidant Properties. Biomolecules. 2019; 9(6):248.

Chicago/Turabian Style

Burmasova, Marina A.; Utebaeva, Aidana A.; Sysoeva, Elena V.; Sysoeva, Maria A. 2019. "Melanins of Inonotus Obliquus: Bifidogenic and Antioxidant Properties" Biomolecules 9, no. 6: 248.

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