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Review

Histamine Intolerance: The Current State of the Art

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Departament de Nutrició, Ciències de l’Alimentació i Gastronomia, Facultat de Farmàcia i Ciències de l’Alimentació, Campus de l’Alimentació de Torribera, Universitat de Barcelona, Av. Prat de la Riba 171, 08921 Santa Coloma de Gramenet, Spain
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Institut de Recerca en Nutrició i Seguretat Alimentària (INSA·UB), Universitat de Barcelona, Av. Prat de la Riba 171, 08921 Santa Coloma de Gramenet, Spain
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Xarxa de Referència en Tecnologia dels Aliments de la Generalitat de Catalunya (XaRTA), C/Baldiri Reixac 4, 08028 Barcelona, Spain
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Author to whom correspondence should be addressed.
Biomolecules 2020, 10(8), 1181; https://doi.org/10.3390/biom10081181
Received: 28 July 2020 / Revised: 10 August 2020 / Accepted: 11 August 2020 / Published: 14 August 2020
(This article belongs to the Special Issue New Developments in Histamine Research)
Histamine intolerance, also referred to as enteral histaminosis or sensitivity to dietary histamine, is a disorder associated with an impaired ability to metabolize ingested histamine that was described at the beginning of the 21st century. Although interest in histamine intolerance has considerably grown in recent years, more scientific evidence is still required to help define, diagnose and clinically manage this condition. This article will provide an updated review on histamine intolerance, mainly focusing on its etiology and the existing diagnostic and treatment strategies. In this work, a glance on histamine intoxication will also be provided, as well as the analysis of some uncertainties historically associated to histamine intoxication outbreaks that may be better explained by the existence of interindividual susceptibility to ingested histamine. View Full-Text
Keywords: histamine; food intolerance; histamine intolerance; histaminosis; histamine intoxication; diamine oxidase (DAO); low-histamine diet; food supplement histamine; food intolerance; histamine intolerance; histaminosis; histamine intoxication; diamine oxidase (DAO); low-histamine diet; food supplement
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MDPI and ACS Style

Comas-Basté, O.; Sánchez-Pérez, S.; Veciana-Nogués, M.T.; Latorre-Moratalla, M.; Vidal-Carou, M.d.C. Histamine Intolerance: The Current State of the Art. Biomolecules 2020, 10, 1181. https://doi.org/10.3390/biom10081181

AMA Style

Comas-Basté O, Sánchez-Pérez S, Veciana-Nogués MT, Latorre-Moratalla M, Vidal-Carou MdC. Histamine Intolerance: The Current State of the Art. Biomolecules. 2020; 10(8):1181. https://doi.org/10.3390/biom10081181

Chicago/Turabian Style

Comas-Basté, Oriol, Sònia Sánchez-Pérez, Maria T. Veciana-Nogués, Mariluz Latorre-Moratalla, and María d.C. Vidal-Carou 2020. "Histamine Intolerance: The Current State of the Art" Biomolecules 10, no. 8: 1181. https://doi.org/10.3390/biom10081181

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