Next Article in Journal
Transcriptome Analysis Reveals Potential Roles of Abscisic Acid and Polyphenols in Adaptation of Onobrychis viciifolia to Extreme Environmental Conditions in the Qinghai-Tibetan Plateau
Next Article in Special Issue
Cold Atmospheric Plasma Is a Potent Tool to Improve Chemotherapy in Melanoma In Vitro and In Vivo
Previous Article in Journal
Vibrational Spectroscopy of Peritoneal Dialysis Effluent for Rapid Assessment of Patient Characteristics
Previous Article in Special Issue
Extracellular Vesicles: Current Analytical Techniques for Detection and Quantification

Encapsulins—Bacterial Protein Nanocompartments: Structure, Properties, and Application

Laboratory “Biomedical Nanomaterials”, National University of Science and Technology “MISiS”, Leninskiy Prospect, 4, 119049 Moscow, Russia
Department of Medical Nanobiotechnoilogy, Pirogov Russian National Research Medical University, Ostrovityanova st, 1, 117997 Moscow, Russia
Department of Nuclear Medicine, TUM School of Medicine, Technical University of Munich, 81675 Munich, Germany
Institute of Biological and Medical Imaging and Institute of Developmental Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany
D. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russia
Author to whom correspondence should be addressed.
Biomolecules 2020, 10(6), 966;
Received: 29 April 2020 / Revised: 21 June 2020 / Accepted: 23 June 2020 / Published: 26 June 2020
(This article belongs to the Special Issue New Trends in Manipulation of Living Cells Behaviour)
Recently, a new class of prokaryotic compartments, collectively called encapsulins or protein nanocompartments, has been discovered. The shell proteins of these structures self-organize to form icosahedral compartments with a diameter of 25–42 nm, while one or more cargo proteins with various functions can be encapsulated in the nanocompartment. Non-native cargo proteins can be loaded into nanocompartments and the surface of the shells can be further functionalized, which allows for developing targeted drug delivery systems or using encapsulins as contrast agents for magnetic resonance imaging. Since the genes encoding encapsulins can be integrated into the cell genome, encapsulins are attractive for investigation in various scientific fields, including biomedicine and nanotechnology. View Full-Text
Keywords: encapsulin; nanocompartment; cell labeling; MRI encapsulin; nanocompartment; cell labeling; MRI
Show Figures

Figure 1

MDPI and ACS Style

Gabashvili, A.N.; Chmelyuk, N.S.; Efremova, M.V.; Malinovskaya, J.A.; Semkina, A.S.; Abakumov, M.A. Encapsulins—Bacterial Protein Nanocompartments: Structure, Properties, and Application. Biomolecules 2020, 10, 966.

AMA Style

Gabashvili AN, Chmelyuk NS, Efremova MV, Malinovskaya JA, Semkina AS, Abakumov MA. Encapsulins—Bacterial Protein Nanocompartments: Structure, Properties, and Application. Biomolecules. 2020; 10(6):966.

Chicago/Turabian Style

Gabashvili, Anna N., Nelly S. Chmelyuk, Maria V. Efremova, Julia A. Malinovskaya, Alevtina S. Semkina, and Maxim A. Abakumov 2020. "Encapsulins—Bacterial Protein Nanocompartments: Structure, Properties, and Application" Biomolecules 10, no. 6: 966.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop