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Article

A Wild Fomes fomentarius for Biomediation of One Pot Synthesis of Titanium Oxide and Silver Nanoparticles for Antibacterial and Anticancer Application

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Department of Epidemic Disease Research, Institute for Research & Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
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Department of Botany, University of Kashmir, Srinagar 190006, India
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Department of Nano-Medicine Research, Institute for Research & Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
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Department of Biophysics, Institute for Research & Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
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Deanship of Scientific Research and Department of Nano-Medicine Research, Institute for Research & Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia
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Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
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Department of Genetic Disease Research, Institute for Research & Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
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Department of Stem Cell Research, Institute for Research & Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia
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Author to whom correspondence should be addressed.
Biomolecules 2020, 10(4), 622; https://doi.org/10.3390/biom10040622
Received: 7 March 2020 / Revised: 6 April 2020 / Accepted: 11 April 2020 / Published: 17 April 2020
The present study offers an alternative method for green synthesis of the formation of two types of nanoparticles (NPs). These NPs, titanium oxide and silver NPs (TiO2 and Ag NPs, respectively), were obtained from the amalgamation of intracellular extract of a wild mushroom, Fomes fomentarius, with aqueous solutions of titanium isopropoxide and silver nitrate, respectively. F. fomentarius was identified phenotypically and by 18S ribosomal RNA gene sequencing (Gene accession no: MK635351). The biosynthesis of TiO2 and Ag NPs was studied and characterized by X-ray diffraction (XRD), diffuse reflectance UV-Visible spectroscopy (DR-UV), fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and transmission electron microscope (TEM). Success was achieved in obtaining NPs of differing sizes and shapes. The antibacterial and anticancer activity of the NPs was significant with morphological damage being caused by both, although Ag NPs (10–20 nm) were found to have profound effects on bacterial and cancer cells in comparison to TiO2 NPs (100–120 nm). These metal NPs, synthesized using wild mushrooms, hold a great potential in biomedicinedue to an effective enzyme combination, which permits them to modify different chemical compounds to less toxic forms, which is required for ecofriendly and safe biomaterials. View Full-Text
Keywords: antibacterial/anticancer; Fomes fomentarius; green synthesis; nanoparticles; silver/titanium antibacterial/anticancer; Fomes fomentarius; green synthesis; nanoparticles; silver/titanium
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MDPI and ACS Style

Rehman, S.; Farooq, R.; Jermy, R.; Mousa Asiri, S.; Ravinayagam, V.; Al Jindan, R.; Alsalem, Z.; Shah, M.A.; Reshi, Z.; Sabit, H.; Alam Khan, F. A Wild Fomes fomentarius for Biomediation of One Pot Synthesis of Titanium Oxide and Silver Nanoparticles for Antibacterial and Anticancer Application. Biomolecules 2020, 10, 622. https://doi.org/10.3390/biom10040622

AMA Style

Rehman S, Farooq R, Jermy R, Mousa Asiri S, Ravinayagam V, Al Jindan R, Alsalem Z, Shah MA, Reshi Z, Sabit H, Alam Khan F. A Wild Fomes fomentarius for Biomediation of One Pot Synthesis of Titanium Oxide and Silver Nanoparticles for Antibacterial and Anticancer Application. Biomolecules. 2020; 10(4):622. https://doi.org/10.3390/biom10040622

Chicago/Turabian Style

Rehman, Suriya, Romana Farooq, Rabindran Jermy, Sarah Mousa Asiri, Vijaya Ravinayagam, Reem Al Jindan, Zainab Alsalem, Manzoor A. Shah, Zafar Reshi, Hussein Sabit, and Firdos Alam Khan. 2020. "A Wild Fomes fomentarius for Biomediation of One Pot Synthesis of Titanium Oxide and Silver Nanoparticles for Antibacterial and Anticancer Application" Biomolecules 10, no. 4: 622. https://doi.org/10.3390/biom10040622

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