1. Introduction
The new era of neutrino experiments is characterized by an unprecedented technological leap. On the one hand, the sophisticated liquid-argon time projection chamber (LArTPC) technology dominates promising projects such as DUNE [
1,
2] and the Short-Baseline Neutrino (SBN) program, which includes experiments such as MicroBooNE, SBND, and ICARUS [
3,
4,
5], establishing
40Ar as a key nuclear target for present and future measurements. On the other hand, this experimental landscape is complemented by large-scale detectors such as Hyper-Kamiokande [
6], based on water, and JUNO [
7], whose goal is to improve the precision of neutrino measurements using hydrocarbon targets.
Although the field has historically relied on carbon or oxygen as theoretical reference nuclei for nuclear modeling, the current experimental program, driven by argon-based detectors and the multi-target strategy of MINER
A [
8], requires going beyond this simplified framework. As neutrino interactions at the GeV scale are explored in neutron-rich media, the assumption that heavy nuclei can be described as simple scaled versions of symmetric nuclei [
9,
10,
11] becomes increasingly questionable. This limitation is particularly evident in the so-called “dip region”, located between the quasielastic (QE) peak and the
resonance.
In this kinematic regime, the cross-section is dominated by two-particle–two-hole excitations induced by meson-exchange currents (2p2h-MEC). A variety of theoretical approaches have been developed to describe these mechanisms with increasing sophistication [
12,
13,
14,
15,
16,
17,
18], reflecting their crucial role in the reliable reconstruction of the incoming neutrino energy. However, as demonstrated in a recent study focused on nuclei with
[
19], neglecting nuclear isospin asymmetry, as well as the use of the same Fermi momenta for protons and neutrons, leads to non-negligible deviations in the predicted nuclear response. These discrepancies increase further with increasing mass number.
The present work constitutes a natural continuation of that study [
19] and addresses this issue through a systematic analysis of 2p2h responses across a broad set of nuclear targets. To this end, we extend microscopic calculations based on an asymmetric nuclear matter description within the Relativistic Mean Field (RMF) framework, previously applied to nuclei such as argon, calcium, and carbon [
19,
20,
21], to an extensive set of seventeen nuclei. This set spans from light systems, such as lithium and helium, to heavy nuclei such as lead and uranium, thereby covering the full mass range relevant for neutrino scattering experiments and for inclusive electron scattering for which experimental data exist for a wide variety of nuclei [
22,
23].
The main objective of this study is to investigate scaling factors that allow for the prediction of the 2p2h response of an arbitrary nucleus starting from that of 12C. In addition, we aim to characterize the nuclear dependence through the available two-particle phase space and nuclear parameters such as the number of nucleons, Fermi momenta, and the effective nuclear mass. The proposed formulation is grounded in a well-defined theoretical framework based on the factorization of the nuclear response and explicitly distinguishes both among different isotopes and among the various emission channels (, , and ). This strategy allows for a more controlled extrapolation from symmetric nuclei to neutron-rich systems, thereby mitigating the dependence on specific nuclear-model assumptions. To achieve this goal, the transverse response is described using a common functional form, with channel-dependent coefficients and phase-space factors, at fixed momentum transfer.
The paper is organized as follows.
Section 2 summarizes the formalism for the treatment of asymmetric 2p2h-MEC responses within the RMF framework. In
Section 3, the nuclear responses are scaled to
12C, and the corresponding proportionality factors are extracted.
Section 4 presents the factorized fitting strategy and the residual analysis. Finally,
Section 5 summarizes the main conclusions of this study and outlines future perspectives.
2. The 2p2h-MEC Formalism
The inclusive lepton-nucleus scattering cross-section is obtained from the contraction of the leptonic tensor with the nuclear hadronic tensor
, which encodes the nuclear dynamics. In addition to one-body processes, further contributions arise from 2p2h excitations induced by two-body electroweak currents. In these mechanisms, the exchanged boson interacts with a pair of nucleons, leading to the emission of two nucleons from the nucleus, as schematically illustrated in
Figure 1.
In this work, we follow the formalism introduced in Ref. [
19] for asymmetric nuclei, where protons and neutrons are treated independently by assigning different Fermi momenta,
and
. Within this framework, the contribution to the hadronic tensor associated with a given two-nucleon emission channel, corresponding to the nucleonic transition
, can be written as
where
(
) and
(
) denote the momenta and energies of the initial (final) nucleons, with effective mass
, and
V is the volume. The delta functions enforce energy and momentum conservation, with
and
denoting the energy and momentum transfer, respectively. The step functions
restrict the phase space to occupied hole states below the corresponding Fermi momentum and to unoccupied particle states above it, for each isospin species. The elementary two-body tensor,
, is constructed from antisymmetrized two-body current matrix elements as
where the sum runs over the spin projections of the initial (
) and final (
) nucleons. The two-body currents
include pion-exchange mechanisms (seagull and pion-in-flight), as well as
excitation(
-forward and
-backward). Their explicit expressions are given in Ref. [
20]. The factor
accounts for the symmetry of the initial/final state, and prevents double counting in channels involving identical nucleons. For inclusive neutrino-induced reactions, the factor takes the value
. For electron-induced reactions,
in the symmetric
and
channels, while
in the asymmetric
channel.
Medium effects are incorporated through an effective description inspired by relativistic mean-field models of nuclear matter [
24]. Within this approach, nucleons propagate with modified single-particle properties that effectively encode the action of scalar and vector mean fields in the nuclear medium. The medium modification is introduced through effective masses for the nucleon and the
resonance:
Here,
and
are effective scalar couplings and
denotes the mean-field expectation value of the scalar field. For observables that depend only on energy differences between initial and final nucleon states, such as the quasielastic 1p-1h response and the seagull and pion-in-flight 2p2h mechanisms, the contribution of the vector mean field cancels explicitly. In contrast, mechanisms involving an intermediate
excitation depend on absolute energies, so that the vector mean field shifts the
pole and modifies both the strength and the shape of the corresponding response.
For simplicity, a universal coupling is assumed [
25], assigning the same vectorial energy to both nucleons and the
resonance,
. The effective nucleon and
masses, together with the proton and neutron Fermi momenta employed for each nucleus, are summarized in
Table 1.
These parameters (
,
,
, and
) are determined through a phenomenological fit to more than 20,000 data points of inclusive electron-nucleus scattering available in the Quasielastic Electron Nucleus Scattering Archive of the University of Virginia [
22,
23]. The resulting values have been further validated against recent high-precision measurements from JLab [
26] and MAMI [
27]. The parameters listed in
Table 1 are consistent with those obtained in previous Superscaling analyses [
17,
28], which employed a single effective Fermi momentum. In this work, we use independent Fermi momenta for protons (
) and neutrons (
) to account for nuclear asymmetry which is equivalent to the value taken in the previous references. In our procedure, the Fermi momentum and the nucleon effective mass are varied to best describe the quasielastic peak in kinematics where the peak is clearly distinguishable (excluding regions of very high or low momentum transfer). Subsequently, the effective
mass
is adjusted to reproduce the
-resonance maximum, ensuring the peak position remains consistent with Relativistic Fermi Gas predictions [
17].
Following the integration procedure described in Ref. [
29], momentum conservation is used to perform the integration over
, and rotational invariance around the direction of the momentum transfer is exploited. The resulting nuclear response functions can be expressed as
where
K labels the different response channels and
denotes the corresponding reduced response function. The integration over the energy-conserving Dirac delta is performed in the center-of-mass system. For electromagnetic interactions, only the longitudinal and transverse responses contribute:
with allowed final-state channels
,
, and
. For charged-current neutrino reactions, five independent response functions contribute:
3. Scaling of 2p2h Responses Relative to Carbon
We compute the 2p2h nuclear response functions for a set of seventeen nuclei at a fixed momentum transfer
MeV/
c, corresponding to a kinematic region where the nuclear response is close to its maximum and which is relevant for modern neutrino experiments. For each nuclear target
X and response channel
K, we define the 2p2h scaling ratio relative to
12C as
As discussed in Ref. [
19], this ratio exhibits only a weak dependence on both the response channel
K and the momentum transfer. In that reference, it is shown that the ratio evaluated at
MeV/
c is very similar to that obtained at
MeV/
c. This behavior is also consistent with other parametrizations available in the literature [
9,
10,
11], where the scaling is found to be largely independent of both the momentum transfer and the specific response considered. Accordingly, in the present analysis we restrict ourselves to the transverse channel and drop the index
K, so that the ratio is simply denoted as
.
In practice, for each nucleus we extract a single effective scaling factor by evaluating the transverse responses at their respective maxima and taking the ratio of peak values, dividing the maximum of the nucleus X by that of .
The peak positions occur at very similar energy transfers, ensuring a well-defined normalization. The scaling ratios are therefore evaluated by taking at the maximum of the transverse response, which for MeV/c lies around –400 MeV.
Figure 2 and
Figure 3 display the transverse 2p2h responses for neutrino-induced reactions in the
and
emission channels, respectively, for the seventeen nuclei considered. The
12C result is shown as a dashed black curve, whereas the other nuclei are rescaled by dividing by their corresponding scaling factor
, quoted in each subpanel.
All responses exhibit a pronounced peak as a function of
, consistent with the leading role of
-driven MEC dynamics in this kinematic domain. In the
channel (
Figure 2), the rescaled curves show a good collapse around the carbon reference. The lightest nuclei (
4He,
6Li,
99Be) display small residual differences, including a mild shift of the peak region with respect to
12C. Within the RMF-inspired effective description, variations in the effective nucleon and
masses and in the corresponding Fermi momenta induce small changes in the peak position and width, effects that are more visible in light systems.
Intermediate-mass nuclei provide the most stable behavior: oxygen, magnesium, and aluminum lie very close to the carbon reference over the peak region. This point matters for applications, since 40Ar and 40Ca also follow the same pattern around the maximum, supporting controlled extrapolations from carbon to argon-based detectors.
For heavy nuclei (tin, lead, uranium), the spread increases, especially at energy transfers above the -peak maximum. Even so, the description remains adequate when one accounts for the strong growth of the absolute 2p2h strength with mass number.
In the
channel (
Figure 3), we find the same overall trend but with an absolute magnitude roughly six times smaller than in the
channel. Here the scaling is visibly less accurate, consistent with the enhanced sensitivity of the
response to neutron excess. The peak region is also broader and less sharply defined. This behavior follows from the interplay of
mechanisms: the
-forward diagram dominates channels with two protons in the final state, whereas the
-backward contribution becomes comparatively more relevant in the
final channel, producing an effective smearing in the
dependence, in line with the analysis in Ref. [
30]. In both channels,
increases generally with atomic number, tracking the approximate proportionality of the 2p2h strength to the nuclear volume. In
Appendix A, we compare the corresponding transverse electromagnetic
T responses for electron-induced reactions in the
,
, and
channels, using coefficients different from those employed for neutrinos.
In
Figure 4 and
Figure 5 we apply the same scaling analysis to the
response in neutrino-induced reactions. The scaling factor is extracted from the
T response and then used for the remaining neutrino responses (
,
,
, and
). In the energy range considered,
T and
dominate the neutrino cross-section. We also obtain the approximate factor
between
T and
, as reported in Ref. [
31]. Overall, the rescaled
T and
responses follow the same pattern, with small channel-dependent differences. For example, in the
final-state channel for
208 the maximum ratio extracted from
is slightly larger than the reference value.
Nevertheless, this analysis provides a useful test to assess whether the scaling behavior identified for the transverse channel also extends to other response functions. This aspect is particularly relevant in the antineutrino case, since the response changes sign, thereby reducing the cross-section and increasing the relative contribution of the other responses.
Table 2 summarizes the scaling ratios
for all nuclei and emission channels, normalized to unity for
12C at
MeV/
c. The ratios grow monotonically with nuclear mass, mirroring the strong increase in the overall 2p2h strength with nuclear size. For a fixed nucleus, channels involving
pairs typically give the largest
, followed by
, while
channels show the weakest mass dependence. The fact that neutrino- and electron-induced reactions exhibit similar global trends supports the use of
as a stable, nucleus-dependent scaling factor.
A striking feature is the much steeper mass dependence of the
and
channels. From helium to uranium, these ratios increase by a factor of about 300, whereas the remaining channels grow by ∼100–120. This trend is quantified by the scaling ratios reported in
Table 2, which span more than an order of magnitude across the nuclear chart. For example, in the neutrino-induced
channel the ratio increases from
for
4He to
for
238U, whereas in the
channel it reaches
for
238U (all values normalized to unity for
12C).
Figure 6 collects all transverse responses rescaled to
12C for both neutrino and electron reactions. After applying the inverse factors
, the results for all nuclei fall within a narrow band around the carbon reference, showing that the leading nuclear dependence can be factorized to a good approximation. The collapse is tight on the low-
side and near the
peak, where the dominant 2p2h strength is concentrated, while a larger spread appears at higher energy transfer, where some nuclei do not scale as well. The
channel shows the largest residual deviations in both electron- and neutrino-induced cases, pointing to a stronger channel-specific nuclear dependence.
We emphasize that this collapse does not imply exact scaling but rather a similar behavior of the rescaled responses across nuclei, with visible residual nuclear dependence that falls within the typical uncertainties associated with 2p2h responses.
4. Factorized Parametrization of the 2p2h Nuclear Response
In this section we introduce the factorized parametrization used to capture the nuclear dependence of the 2p2h responses. The input is the set of scaling ratios listed in
Table 2, extracted from the microscopic RMF calculations at
and at the energy transfer corresponding to the maximum of the
peak,
.
Previous studies, such as Refs. [
19,
31,
32], have shown that the scaling behavior of the 2p2h response can be partially interpreted in terms of a phase-space proportionality. While this approach provides a reasonable description for nuclei with similar mass numbers (e.g.,
12C and
40Ca), significant deviations emerge for heavier systems such as lead or uranium, indicating that additional sources of nuclear dependence must be taken into account. Motivated by these observations, we decompose the nuclear response in Equation (
4) within a factorized scheme of the form
It is important to emphasize that Equation (
8) does not introduce any approximation. It follows exactly from the definition of the averaged reduced response
. This factorized form isolates a volume-like contribution
, a reduced phase-space factor
, and an averaged reduced single-pair response
, which contains the remaining dynamical and many-body nuclear dependence. We define the scaling ratio relative to
12C as
with
In our implementation, the volume-like factor entering the normalization is defined under the assumption that protons and neutrons occupy the same spatial volume within the nucleus. Within this picture, the proton and neutron densities differ through their respective Fermi momenta, but the geometric volume is taken to be common. Under this assumption, the volume factor can be written equivalently as
so that
is fully determined by
Z (or by
N), and the corresponding Fermi momentum.
The factor
represents the 2p2h phase-space contribution with the volume term removed. Although it is formally defined as a seven-dimensional integral, it can be accurately approximated by an analytical expression obtained within the frozen approximation and by neglecting Pauli blocking effects, as discussed in Equations (39) and (40) of Ref. [
33]. Within this approximation, the phase-space factor can be rewritten in the RMF framework allowing for different proton and neutron Fermi momenta as
where the ratio
is given by
This expression shows explicitly that the available two-particle phase space grows rapidly with increasing energy transfer
and approaches a constant value in the asymptotic limit
, leading to
In the present implementation, we factor out only the leading dependence on the proton and neutron Fermi momenta. Any remaining kinematic and dynamical dependence either cancels explicitly when forming the scaling ratio or is retained in the reduced response. One example of the latter is the effective nucleon mass, which also enters the phase-space structure and whose contribution is ultimately absorbed into the reduced-response scaling function
. Accordingly, the phase-space term that we factorize for each emission channel is taken to be
While the volume and phase-space factors can be computed using analytical expressions, the reduced response involves a much more complex dynamical structure. For this reason, all the remaining nuclear dependence is collected in the reduced-response scaling function term
. We model
with an ansatz that encodes (i) proton–neutron imbalance through the Fermi momenta
and
, and (ii) RMF medium effects through the nucleon effective mass. Note that, once the leading volume dependence has been factored out, the only quantities that vary from nucleus to nucleus in this model are the proton and neutron Fermi momenta and the effective mass. Accordingly, we parametrize
as
The parametrization consists of three terms. The first term is dependent on the proton content of the nucleus by the proton Fermi momentum, the second term is proportional to the neutron Fermi momentum, and the third term accounts for effective-mass effects arising from the RMF framework. In a simple Fermi gas model, this last contribution, associated with the coefficient
, would not be required.
We use
12C as the reference nucleus, fixing
and
. We also remark that the effective
mass,
, reported in
Table 1, is an input of the microscopic RMF calculation and is not treated as an independent scaling variable. Its nuclear dependence is assumed to follow the same scaling behavior as the effective nucleon mass.
The fitted coefficients reported in
Table 3 exhibit a clear dependence on the emission channel, reflecting the different dynamical mechanisms that govern each reaction. The relative weight of the
and
terms varies across channels, effectively encoding the sensitivity to proton-neutron imbalance through the different evolution of the two Fermi momenta with nuclear number. The effective-mass coefficient
contributes with the same sign and with a similar magnitude in all cases, highlighting the role of RMF medium effects.
The values of
(the coefficient of determination of the linear regression) reported in the table provide a global measure of the quality of the parametrization for each channel. The results demonstrate a uniformly high quality of the fit across all channels, with
above 0.95. In
Figure 7, we display the results of the separated channel fit as a function of the mass number
A. We observe that, for all channels, the factor
tends to decrease with increasing nuclear size and approaches a nearly constant value for heavy nuclei. The figure also illustrates the relatively very good description in all channel. The
channel, with
, is particularly relevant for neutrino-induced reactions, where it provides the dominant contribution.
It is important to emphasize, however, that the present parametrization is not intended to reproduce the microscopic 2p2h response of a specific nucleus-which is obtained from the underlying RMF calculations—but rather to describe how this response evolves across different nuclear targets over a wide mass range. To quantify the quality of the fit over this nuclear range, a quantitative validation is therefore performed through the analysis of the relative residuals shown in
Figure 8, defined as
The resulting parametrization reproduces the main trends in the scaling factors across different nuclei and emission channels. As shown by the residual analysis, the relative residuals remain typically within
, corresponding to relative deviations of the order of
. As shown in
Figure 8, the relative residuals display the largest dispersion for the lightest nuclei, where sizable positive and negative deviations are observed. For intermediate-mass systems, the residuals cluster more tightly around zero, with most values lying within the
band and exhibiting a smooth dependence on nuclear size. For the heaviest nuclei, the dispersion increases again, although it remains less pronounced than in the lightest systems and does not show a strong systematic bias.
5. Conclusions
In this work we investigated the nuclear dependence of two-particle–two-hole meson-exchange current contributions to inclusive electron–nucleus and neutrino-nucleus scattering within the relativistic mean-field framework, extending microscopic calculations from carbon to a broad set of nuclear targets ranging from light to heavy systems.
We find that the dominant nuclear dependence of the transverse two-particle responses can be largely absorbed into a nucleus-dependent scaling factor relative to carbon. For most medium-mass nuclei, the response shapes are similar in the vicinity of the peak, while departures from perfect scaling are mainly observed for the lightest and heaviest systems and at large energy transfers, where subleading nuclear effects become more relevant.
On the basis of these observations, we adopt a factorized form for the scaling ratio, separating volume and reduced phase-space contributions and collecting the remaining nuclear dependence in a reduced-response scaling function . We parametrize using the proton and neutron Fermi momenta and the RMF effective mass, obtaining a compact representation of the microscopic results across nuclei rather than a statistical fit in the strict sense.
The overall quality of the parametrization is moderate, capturing the main trends in the scaling ratios across the nuclear chart. For medium-mass nuclei, the relative deviations are typically below the ∼10% level, as can be inferred from the residual analysis. Larger deviations are concentrated in the lightest and heaviest systems, reflecting both genuine nuclear-structure effects and the limitations imposed by the restricted set of microscopic calculations considered in this work, which spans 16 nuclei. These results illustrate that achieving a fully universal description across all nuclei and emission channels remains a challenging task within the present dataset.
Despite these limitations, the proposed scaling strategy provides a practical and transparent framework to extrapolate microscopic RMF calculations from a carbon reference to other nuclear targets of experimental interest, including neutron-rich nuclei. Its simplicity makes it well suited for exploratory implementations in neutrino event generators, where it can support a more controlled treatment of two-particle–two-hole contributions.
In future work, we plan to apply the same factorized scaling prescription to antineutrino-induced reactions. We will also explore comparisons with other microscopic 2p2h models, extend the set of benchmark nuclei, and confront the results with available experimental data. These steps will help to provide a more reliable and controlled input for neutrino oscillation experiments, in particular for analyses involving heavy targets.