Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX
Abstract
:1. Introduction
2. Membrane-Localized Metabolic Transport Proteins
2.1. Bicarbonate Transporters
2.2. Essential Amino Acid Transporters
2.3. Glutamine Transporters
3. Cell Adhesion/Migration/Invasion Proteins
3.1. Association with Integrins and MMP14 in Pseudopodia
3.2. Functional Role of a CAIX-MMP14 Interaction at Invadopodia
4. Targeting CAIX Activity in Hypoxic Solid Tumors
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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McDonald, P.C.; Swayampakula, M.; Dedhar, S. Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX. Metabolites 2018, 8, 20. https://doi.org/10.3390/metabo8010020
McDonald PC, Swayampakula M, Dedhar S. Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX. Metabolites. 2018; 8(1):20. https://doi.org/10.3390/metabo8010020
Chicago/Turabian StyleMcDonald, Paul C., Mridula Swayampakula, and Shoukat Dedhar. 2018. "Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX" Metabolites 8, no. 1: 20. https://doi.org/10.3390/metabo8010020