Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Experimental Procedures
2.3. Milking
2.4. Amino Acid and Polyamine Analysis
2.5. Sleep-like Behavior Observation
2.6. Statistical Analysis
3. Results
3.1. Concentration of L-Ornithine in Mother Plasma and in Milk
3.2. Levels of L-Ornithine in Maternal Plasma, the Mammary Glands, and Milk after Oral Administration of L-Ornithine
3.3. Polyamine Levels in Milk after Oral Administration of L-Ornithine
3.4. Sleep-like Behavior of Mouse Pups Supplemented with L-Ornithine at Different Concentrations
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Takakura, M.; Nagamachi, S.; Nishigawa, T.; Takahashi, Y.; Furuse, M. Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups. Metabolites 2022, 12, 1241. https://doi.org/10.3390/metabo12121241
Takakura M, Nagamachi S, Nishigawa T, Takahashi Y, Furuse M. Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups. Metabolites. 2022; 12(12):1241. https://doi.org/10.3390/metabo12121241
Chicago/Turabian StyleTakakura, Mayumi, Satsuki Nagamachi, Takuma Nishigawa, Yoshihiro Takahashi, and Mitsuhiro Furuse. 2022. "Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups" Metabolites 12, no. 12: 1241. https://doi.org/10.3390/metabo12121241
APA StyleTakakura, M., Nagamachi, S., Nishigawa, T., Takahashi, Y., & Furuse, M. (2022). Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups. Metabolites, 12(12), 1241. https://doi.org/10.3390/metabo12121241