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Article

Antibacterial, Antibiofilm, and Antischistosomal Activity of Montrichardia linifera (Arruda) Schott (Araceae) Leaf Extracts

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Postgraduate Program in Biotechnology (PPGBIOTEC), Federal University of the Parnaíba Delta (UFDPAR), Parnaiba 64200-000, Brazil
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Medicinal Chemistry and Biotechnology Research Group (QUIMEBIO), Federal University of Maranhão (UFMA), Sao Bernardo 65550-000, Brazil
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Natural Sciences and Biotechnology Research Group (CIENATEC), Federal University of Maranhão (UFMA), Grajau 65940-000, Brazil
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Laboratory of Natural Products and Experimental Neurochemistry (LAPPNEX), Federal University of Piauí (UFPI), Teresina 64000-000, Brazil
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Biodiversity and Biotechnology Research Center (BIOTEC), Federal University of the Parnaíba Delta (UFDPAR), Parnaiba 64200-000, Brazil
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University Veterinary Hospital, Federal University of Piauí (UFPI), Bom Jesus 59270-000, Brazil
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Natural Products Chemistry Laboratory (LQPN), Federal University of Maranhão (UFMA), Sao Luis 16200-029, Brazil
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Research Center for Neglected Diseases (NPDN), University of Guarulhos (UNG), Guarulhos 07023-070, Brazil
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Author to whom correspondence should be addressed.
Academic Editor: Hermann Stuppner
Sci. Pharm. 2021, 89(3), 31; https://doi.org/10.3390/scipharm89030031
Received: 22 March 2021 / Revised: 26 April 2021 / Accepted: 13 May 2021 / Published: 5 July 2021
With a broad ethnopharmacological tradition in Brazil, Montrichardia linifera has been reported as a potent antirheumatic, antimicrobial, and antiprotozoan agent. However, there is a lack of studies on its effect on bacterial biofilm formation and Schistosoma mansoni worms. This study reports the effects of antibacterial, antibiofilm, and antischistosomal properties of leaf extracts of M. linifera. Phytochemical screening and identification of the main compounds of the extracts were performed. All the extracts evaluated showed antibacterial activity at the concentrations tested. We checked for the presence of flavonoids and derivatives of phenolic acids by the presence of spectra with bands characteristic of these classes in the sample analyzed. The antibacterial assays showed that the best MICs corresponded to 125 µg/mL against Enterococcus faecalis ATCC 29212 in all fractions. The ethanolic and methanolic extracts showed the ability to inhibit biofilm of Staphylococcus aureus ATCC 25123. For the antischistosomal activity, only the acetone and ethyl acetate extracts had a significant effect against helminths, with potent activity at a concentration of 50 µg/mL, killing 100% of the worms after 72 h of incubation. The M. linifera leaf extracts showed antibacterial activity, biofilm inhibition capacity, and anthelmintic activity against S. mansoni. View Full-Text
Keywords: Montrichardia linifera; biofilm; antibacterial; Schistosoma mansoni; leaf extract Montrichardia linifera; biofilm; antibacterial; Schistosoma mansoni; leaf extract
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MDPI and ACS Style

Lima, C.; Andrade, D.; Moreira, G.; Sousa, Â.; Leal, A.; Figuerêdo, J.; Furtado, P.; Feitosa, C.; Araujo, A.; Andrade, I.; Miranda, J.; Lima, A.; Rocha, C.; Silva, T.; Mengarda, A.C.; de Moraes, J.; Rocha, J. Antibacterial, Antibiofilm, and Antischistosomal Activity of Montrichardia linifera (Arruda) Schott (Araceae) Leaf Extracts. Sci. Pharm. 2021, 89, 31. https://doi.org/10.3390/scipharm89030031

AMA Style

Lima C, Andrade D, Moreira G, Sousa Â, Leal A, Figuerêdo J, Furtado P, Feitosa C, Araujo A, Andrade I, Miranda J, Lima A, Rocha C, Silva T, Mengarda AC, de Moraes J, Rocha J. Antibacterial, Antibiofilm, and Antischistosomal Activity of Montrichardia linifera (Arruda) Schott (Araceae) Leaf Extracts. Scientia Pharmaceutica. 2021; 89(3):31. https://doi.org/10.3390/scipharm89030031

Chicago/Turabian Style

Lima, Cleiane, Dallyla Andrade, Gleidiany Moreira, Ângelo Sousa, Antonia Leal, Juliana Figuerêdo, Pedro Furtado, Chistiane Feitosa, Alyne Araujo, Ivanilza Andrade, João Miranda, Aldilene Lima, Cláudia Rocha, Taís Silva, Ana C. Mengarda, Josué de Moraes, and Jefferson Rocha. 2021. "Antibacterial, Antibiofilm, and Antischistosomal Activity of Montrichardia linifera (Arruda) Schott (Araceae) Leaf Extracts" Scientia Pharmaceutica 89, no. 3: 31. https://doi.org/10.3390/scipharm89030031

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