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Sci. Pharm. 2019, 87(1), 3; https://doi.org/10.3390/scipharm87010003

The Anti-Inflammatory Activity of Nigella sativa Balm Sticks

Department of Pharmacy and Science, Universitas Muhammadiyah Prof. Dr HAMKA (UHAMKA), Jakarta 13460, Indonesia
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Received: 28 December 2018 / Revised: 9 January 2019 / Accepted: 9 January 2019 / Published: 14 January 2019
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Abstract

Nigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%), low leucocytes count (43.55% lower than control) as well as a notable TNF-α concentration (50% lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm stick was effective for both acute and sub-acute forms of inflammation. View Full-Text
Keywords: Nigella sativa; anti-inflammatory; balm; topical Nigella sativa; anti-inflammatory; balm; topical
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Dwita, L.P.; Yati, K.; Gantini, S.N. The Anti-Inflammatory Activity of Nigella sativa Balm Sticks. Sci. Pharm. 2019, 87, 3.

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