Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015).
Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence.
Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Sci. Pharm. 2013, 81(2), 309-328; https://doi.org/10.3797/scipharm.1302-08 (registering DOI)
An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases
Chemistry Department, Islamia College University, Peshawar-25120, Pakistan
Institute of Chemical Sciences, University of Peshawar, Peshawar-25120, Pakistan
Author to whom correspondence should be addressed.
Received: 18 February 2013 / Accepted: 28 March 2013 / Published: 28 March 2013
PDF [261 KB, uploaded 27 September 2016]
Abstract The production of metallo-β-lactamases is the most important strategy by which pathogenic bacteria become resistant to currently known β-lactam antibiotics. The emergence of these enzymes is particularly concerning for the future treatment of bacterial infections. There are no clinically available drugs capable of inhibiting any of the metallo-β-lactamases, so there is an urgent need to find such inhibitors. In this review, an up-to-date status of the inhibitors investigated for the inhibition of metallo-β-lactamases has been given so that this rich source of structural information of presently known metallo-β-lactamases could be helpful in generating a broad-spectrum potent inhibitor of metallo-β-lactamases.
This is an open access article distributed under the Creative Commons Attribution License
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Share & Cite This Article
MDPI and ACS Style
FARIDOON; ISLAM, N.U. An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases. Sci. Pharm. 2013, 81, 309-328.
FARIDOON, ISLAM NU. An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases. Scientia Pharmaceutica. 2013; 81(2):309-328.
FARIDOON; ISLAM, Nazar U. 2013. "An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases." Sci. Pharm. 81, no. 2: 309-328.
Show more citation formats
Show less citations formats
[Return to top]
For more information on the journal statistics, click here
Multiple requests from the same IP address are counted as one view.