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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2011, 79(1), 175-180; (registering DOI)

Phenolics from Rhagadiolus stellatus (Asteraceae, Cichorieae)

Institut für Pharmazie, Universität Innsbruck, Josef-Moeller-Haus, Innrain 52, A-6020 Innsbruck, Austria
Institut für Lebensmitteluntersuchung Innsbruck, Österreichische Agentur für Gesundheit und Ernährungssicherheit, Technikerstraße 70, A-6020 Innsbruck, Austria
Institut für Organische Chemie, Universität Innsbruck, Innrain 52a, A-6020 Innsbruck, Austria
Author to whom correspondence should be addressed.
Received: 30 November 2010 / Accepted: 3 February 2011 / Published: 7 February 2011
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Rhagadiolus stellatus Gaertn., a Mediterranean member of the Cichorieae tribe of the Asteraceae family used as a food plant, was analyzed for its spectrum of phenolic compounds. Kaempferol 3-O-β-glucoside 1, kaempferol 3-O-β- rutinoside (nicotiflorin) 2, quercetin 3-O-β-glucoside 3, and luteolin 4 were isolated from the n-butanol layer of a methanolic extract of whole plants of Rh. stellatus of Spanish origin by repeated Sephadex LH-20 column chromatography. Structures were determined based on NMR and MS data as well as by comparison with literature data. Additionally, chlorogenic acid 5 and 3,5-dicaffeoylquinic acid 6 were detected by HPLC/DAD and HPLC/MS. Chemosystematic implications of the presented findings are discussed in comparison with other members of the Cichorieae tribe.
Keywords: Rhagadiolus stellatus Gaertn.; Asteraceae; Cichorieae; Flavonoids; Chemosystematics Rhagadiolus stellatus Gaertn.; Asteraceae; Cichorieae; Flavonoids; Chemosystematics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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KRIMPLSTÄTTER, R.; MA, B.; SPITALER, R.; ELLMERER, E.; ZIDORN, C. Phenolics from Rhagadiolus stellatus (Asteraceae, Cichorieae). Sci. Pharm. 2011, 79, 175-180.

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