Next Article in Journal
"Classics in Spectroscopy"
Previous Article in Journal
P-gp Inhibitory Potential of Phospholipids
Article Menu

Article Versions

Export Article

Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Open AccessConference Report
Sci. Pharm. 2010, 78(3), 727-728; (registering DOI)

Compartmental Modelling of the Pharmacokinetics of an Efflux Transporter

School of Engineering, Warwick University, Coventry, United Kingdom
AstraZeneca R&D, Alderley Park, Cheshire, United Kingdom
Author to whom correspondence should be addressed.
Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
PDF [129 KB, uploaded 11 October 2016]


A mathematical model has been developed describing the pharmacokinetics of Hoechst 33342 following administration into a culture medium containing a population of transfected cells (HEK293 hBCRP) with a potent inhibitor of the BCRP, Fumitremorgin C (FTC), present. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

GRANDJEAN, T.R.B.; YATES, J.T.W.; CHAPPELL, M.J. Compartmental Modelling of the Pharmacokinetics of an Efflux Transporter. Sci. Pharm. 2010, 78, 727-728.

Show more citation formats Show less citations formats

Article Metrics

Article Access Statistics



[Return to top]
Sci. Pharm. EISSN 2218-0532 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top