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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2010, 78(3), 556; (registering DOI)

Non-Invasive Oligonucleotide Delivery System Based on a Thiolated Polymer: Development and In Vitro Evaluation

Department of Pharmaceutics, Faculty of Pharmacy, Gadjah Mada University, Sekip Utara, 55281 Yogyakarta, Indonesia
Department of Pharmaceutical Technology, Institute of Pharmacy, Leopold-Franzens-University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
Author to whom correspondence should be addressed.
Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
PDF [129 KB, uploaded 29 September 2016]


It was the purpose of this study to develop an oral oligonucleotide delivery system based on thiolated polymer/ reduced glutathione (GSH) system providing protective effect towards nucleases, permeation enhancement and controlled drug release. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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MARTIEN, R.; HOYER, H.; PERERA, G.; BERNKOP-SCHNÜRCH, A. Non-Invasive Oligonucleotide Delivery System Based on a Thiolated Polymer: Development and In Vitro Evaluation. Sci. Pharm. 2010, 78, 556.

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