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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2010, 78(3), 483-492; (registering DOI)

Investigation of the Volatile Fraction of Rosemary Infusion Extracts

Institute of Pharmaceutical Sciences, University of Graz, Universitätsplatz 4/1, 8010, Graz, Austria
Author to whom correspondence should be addressed.
Received: 29 April 2010 / Accepted: 16 June 2010 / Published: 16 June 2010
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The relative proportions of chemical classes (hydrocarbons, oxides, alcohols, ketones, esters) in the essential oil of rosemary (Rosmarinus officinalis L., Lamicaeae) and in the volatile fraction of the infusion extracts were examined and showed remarkable differences. The volatile compounds of the infusion were isolated by two different methods, hydrodistillation and solid phase extraction (SPE). The main constituents of the volatile fraction of the infusion were (hydrodistillation/SPE): 1,8-cineole (42.4%/44.7%), camphor (31.4%/31.8%), α-terpineol (8.6%/8.1%) and borneol (8.3%/7.8%). The qualitative and quantitative composition of the volatile compounds of the infusion was compared to the essential oil isolated by hydrodistillation directly from the leaves. The major constituents of the essential oil of the leaves were 1,8-cineole (41.6%), camphor (17.0%), α-pinene (9.9%), α-terpineol (4.9%) and borneol (4.8%). Comparison of the total essential oil yield quantified by hydrodistillation of the infusion (0.36% v/w) with the essential oil yield of the leaves (1.84% v/w) revealed that only 19.6% of the initial oil could be extracted by infusion.
Keywords: Rosmarinus officinalis; Infusion; GC-MS; Essential oil; SPE Rosmarinus officinalis; Infusion; GC-MS; Essential oil; SPE
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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TSCHIGGERL, C.; BUCAR, F. Investigation of the Volatile Fraction of Rosemary Infusion Extracts. Sci. Pharm. 2010, 78, 483-492.

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