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Antitrypanosomal Activity of 4-Aminobicyclo[2.2.2]octane Derivatives
Institute of Pharmaceutical Sciences, Karl-Franzens-University of Graz, Universitätsplatz 1, 8010 Graz, Austria
Author to whom correspondence should be addressed.
Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Every year about half a million people are infected with Human African Trypanosomiasis (HAT) and more than 40.000 people die from this disease . Infections with Trypanosoma brucei rhodesiense
, which is the more virulent of the two causative organisms, can only be treated with two drugs, suramin and melarsoprol, which can cause severe side effects and which have to be administered by painful injections.[...]
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WEIS, R.; FAIST, J.; SEEBACHER, W. Antitrypanosomal Activity of 4-Aminobicyclo[2.2.2]octane Derivatives. Sci. Pharm. 2009, 77, 214.
WEIS R, FAIST J, SEEBACHER W. Antitrypanosomal Activity of 4-Aminobicyclo[2.2.2]octane Derivatives. Scientia Pharmaceutica. 2009; 77(Posters (PO)):214.
WEIS, R.; FAIST, J.; SEEBACHER, W. 2009. "Antitrypanosomal Activity of 4-Aminobicyclo[2.2.2]octane Derivatives." Sci. Pharm. 77, Posters (PO): 214.
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