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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2008, 76(4), 599-604;

First Total Synthesis of Ergosta-5,8-dien-3β-ol Erste Totalsynthese von Ergosta-5,8-dien-3β-ol

Department Pharmazie – Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität München, Butenandtstr. 5–13, 81377 München, Germany
Author to whom correspondence should be addressed.
Received: 23 October 2008 / Accepted: 12 November 2008 / Published: 13 November 2008
PDF [222 KB, uploaded 28 December 2016]


The first total synthesis of ergosta-5,8-dien-3β-ol, an uncommon sterol previously isolated from an alga and several microorganisms, has been developed. For the first time, a full set of spectroscopic data of this sterol is presented.
Keywords: (3β)-Ergosta-5,8-dien-3-ol; Sterol; Hydrogenation; Birch reduction; Total synthesis (3β)-Ergosta-5,8-dien-3-ol; Sterol; Hydrogenation; Birch reduction; Total synthesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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GIERA, M.; BRACHER, F. First Total Synthesis of Ergosta-5,8-dien-3β-ol Erste Totalsynthese von Ergosta-5,8-dien-3β-ol. Sci. Pharm. 2008, 76, 599-604.

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