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Diseases 2015, 3(3), 122-135;

Diagnosis of Helicobacter pylori: Changes towards the Future

Institute of Medical Microbiology, Immunology and Hygiene, TU-Munich, Troger Str.30, 81675 Munich, Germany
ImevaX GmbH, Grillparzer Str.18, 81675 Munich, Germany
German Center for Infection Research (DZIF), Partner site Munich, Troger Str.30, 81675 Munich, Germany
Author to whom correspondence should be addressed.
Academic Editor: Marina de Bernard
Received: 12 March 2015 / Revised: 18 June 2015 / Accepted: 19 June 2015 / Published: 29 June 2015
(This article belongs to the Special Issue Helicobacter Pylori Infection)
Full-Text   |   PDF [661 KB, uploaded 29 June 2015]


Since the first evidence demonstrating the dramatically high incidence of H. pylori infection and the subsequent medical challenges it incurs, health management of H. pylori infection has been a high priority for health authorities worldwide. Despite a decreasing rate of infection in western countries, prevalence of H. pylori infection in developing and in some industrial countries is still very high. Whereas treatment and vaccination against H. pylori is a contemporary issue in medical communities, selective treatment and prior high-throughput screening of the subject population is a major concern of health organizations. So far, diagnostic tests are either elaborative and require relatively advanced medical care infrastructure or they do not fulfill the criteria recommended by the Maastricht IV/Florence consensus report. In this review, in light of recent scientific studies, we highlight current and possible future approaches for the diagnosis of H. pylori. We point out that novel non-invasive tests may not only cover the requirements of gold standard methods in H. pylori detection but also offer the potential for risk stratification of infection in a high throughput manner. View Full-Text
Keywords: Helicobacter pylori; diagnosis; invasive methods; non-invasive methods Helicobacter pylori; diagnosis; invasive methods; non-invasive methods
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Kalali, B.; Formichella, L.; Gerhard, M. Diagnosis of Helicobacter pylori: Changes towards the Future. Diseases 2015, 3, 122-135.

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