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Fibers 2018, 6(2), 23;

Antifungal Composite Fibers Based on Cellulose and Betulin

A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 119991 Moscow, Russia
Department of Biotechnology, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia
Department of Chemistry and Chemical Technology, Atyrau State University named after Kh. Dosmukhamedov, Atyrau 060011, Kazakhstan
Gause Institute of New Antibiotics, 119021 Moscow, Russia
Author to whom correspondence should be addressed.
Received: 2 February 2018 / Revised: 23 February 2018 / Accepted: 15 March 2018 / Published: 18 April 2018
(This article belongs to the Special Issue Current Developments in Cellulose Based Nanomaterials)
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Composite fibers and films based on cellulose and betulin were spun for the first time from solutions in N-methylmorpholine-N-oxide using the dry–wet jet method. The rheological properties of the composite solutions did not reveal any fundamental difference from those of the cellulose solutions. Introduction of betulin into the cellulose matrix (up to 10%) led to a decrease in the mechanical properties of the obtained fibers. The structure of the composite fibers was analyzed using SEM and X-ray diffraction methods. It was shown that the introduction of an additive into the cellulose matrix led to a decrease in the structural ordering of the cellulose. Comparative studies of the antibacterial activity of the composite films on Escherichia coli (E. coli) were carried out. The antifungal activity of the composite films was estimated using the strain of the O-97 Trichoderma viride Pers ex Fr (Gause Institute of New Antibiotics, Moscow, Russia). View Full-Text
Keywords: cellulose; betulin; N-methylmorpholine-N-oxide; composite fibers; structure; tensile properties; antifungal characterization cellulose; betulin; N-methylmorpholine-N-oxide; composite fibers; structure; tensile properties; antifungal characterization

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Makarov, I.; Vinogradov, M.; Gromovykh, T.; Lutsenko, S.; Feldman, N.; Shambilova, G.; Sadykova, V. Antifungal Composite Fibers Based on Cellulose and Betulin. Fibers 2018, 6, 23.

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