Next Article in Journal
Investigation on the Surface Properties of 5A12 Aluminum Alloy after Nd: YAG Laser Cleaning
Previous Article in Journal
Influence of the Hamaker Constant on the Value of the Critical Thickness of Foam Films
Open AccessArticle

Large-Area Coating of Previtamin D3 Based on Roll-to-Roll Processing

1
Department of Mechanical Design and Production Engineering, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea
2
School of Mechanical Engineering, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Coatings 2019, 9(9), 577; https://doi.org/10.3390/coatings9090577
Received: 22 August 2019 / Revised: 5 September 2019 / Accepted: 9 September 2019 / Published: 11 September 2019
We propose a roll-to-roll process for vitamin D3 patch production. A solution of 7-dehydrocholesterol is applied to a plastic film by roll-to-roll slot-die coating and dried by a far-infrared lamp. Upon exposure to ultraviolet B irradiation, these films are converted to previtamin D3 films. After heat-treating the previtamin D3 film, high-performance liquid chromatography measurements are performed using commercial vitamin D3 as a standard sample. The results confirm that vitamin D3 can be produced by large-area coating and post-treatment processes. Specifically, 3.16 ± 0.746 mg of vitamin D3 is obtained through ultraviolet B irradiation and heat-treatment of 24.8 ± 1.44 mg of coated 7-dehydrocholesterol. View Full-Text
Keywords: slot-die coating; roll-to-roll (R2R); vitamin D3; ultraviolet B (UVB); high-performance liquid chromatography (HPLC) slot-die coating; roll-to-roll (R2R); vitamin D3; ultraviolet B (UVB); high-performance liquid chromatography (HPLC)
Show Figures

Graphical abstract

MDPI and ACS Style

Park, J.; Min, Y.; Lee, J.; Jeong, H.; Noh, Y.; Shin, K.-H.; Lee, D. Large-Area Coating of Previtamin D3 Based on Roll-to-Roll Processing. Coatings 2019, 9, 577.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

1
Back to TopTop