Ti-SLActive and TiZr-SLActive Dental Implant Surfaces Promote Fast Osteoblast Differentiation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Cell Isolation and Culture
2.3. DAPI Staining of the Cells
2.4. Acridin Orange Staining—Microscopy
2.5. BSP, OC and Col-1 Expression
2.6. Acridin Orange Staining—Flow Cytometry
2.7. NO Production—Flow Cytometry
2.8. Reactive Oxygen Species/Reactive Nitrogen Species (ROS/RNS) Production—Flow Cytometry
2.9. Statistical Analysis
3. Results
3.1. Cell Proliferation
3.2. Cell Morphology
3.3. Cell Cluster Formation
3.4. Osteocalcin, Bone Sialoprotein and Collagen Type I
3.5. Production of NO and ROS/RNS in Large Granular Cells
3.6. Autophagy Induction
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Kaluđerović, M.R.; Krajnović, T.; Maksimović-Ivanić, D.; Graf, H.-L.; Mijatović, S. Ti-SLActive and TiZr-SLActive Dental Implant Surfaces Promote Fast Osteoblast Differentiation. Coatings 2017, 7, 102. https://doi.org/10.3390/coatings7070102
Kaluđerović MR, Krajnović T, Maksimović-Ivanić D, Graf H-L, Mijatović S. Ti-SLActive and TiZr-SLActive Dental Implant Surfaces Promote Fast Osteoblast Differentiation. Coatings. 2017; 7(7):102. https://doi.org/10.3390/coatings7070102
Chicago/Turabian StyleKaluđerović, Milena R., Tamara Krajnović, Danijela Maksimović-Ivanić, Hans-Ludwig Graf, and Sanja Mijatović. 2017. "Ti-SLActive and TiZr-SLActive Dental Implant Surfaces Promote Fast Osteoblast Differentiation" Coatings 7, no. 7: 102. https://doi.org/10.3390/coatings7070102