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Case Report

Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature

1
Independent Researcher, San Juan Capistrano, CA 92675, USA
2
School of Medicine, University College Dublin, D07 A8NN Dublin, Ireland
3
Infectious Diseases Department, Mater Misericordiae University Hospital, D07 K201 Dublin, Ireland
*
Author to whom correspondence should be addressed.
Antibiotics 2019, 8(4), 223; https://doi.org/10.3390/antibiotics8040223
Received: 28 October 2019 / Revised: 8 November 2019 / Accepted: 9 November 2019 / Published: 14 November 2019
(This article belongs to the Special Issue Antibiotics Resistance of Borrelia)
This report describes the case of an individual who was clinically diagnosed with Lyme borreliosis and initially responded to standard antibiotic therapy. Subsequent to treatment cessation, the patient experienced symptomatic rebound and failed to respond to a second course of the same antibiotic. The patient was eventually diagnosed with both Borrelia and Anaplasma infections by serological testing performed in a private laboratory. Following a two-month course of combination antibiotic therapy, the patient responded clinically, with a return to almost normal functioning. We discuss this case in the context of recent pre-clinical research examining potential Borrelial persistence despite antibiotic therapy. View Full-Text
Keywords: borreliosis; tick-borne infections; persistent infections; post-treatment lyme disease syndrome borreliosis; tick-borne infections; persistent infections; post-treatment lyme disease syndrome
MDPI and ACS Style

Moysa, C.; Murtagh, R.; Lambert, J.S. Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature. Antibiotics 2019, 8, 223. https://doi.org/10.3390/antibiotics8040223

AMA Style

Moysa C, Murtagh R, Lambert JS. Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature. Antibiotics. 2019; 8(4):223. https://doi.org/10.3390/antibiotics8040223

Chicago/Turabian Style

Moysa, Cozette, Ross Murtagh, and John S. Lambert. 2019. "Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature" Antibiotics 8, no. 4: 223. https://doi.org/10.3390/antibiotics8040223

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