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Antibiotics 2014, 3(3), 450-460;

A Point Prevalence Survey of Antibiotic Use in 18 Hospitals in Egypt

Global Disease Detection and Response Center, US Naval Medical Research Unit, No.3, Cairo 11517, Egypt
Ministry of Health and Population, Cairo 11516, Egypt
Cairo University Hospitals, Giza 11562, Egypt
Alexandria University Hospitals, Alexandria 21111, Egypt
Minya University Hospitals, Minya 61519, Egypt
Ain Shams University Hospitals, Cairo 11591, Egypt
Azhar University Hospitals, Cairo 11517, Egypt
Weill Cornell Medical College, New York, NY 10065, USA
Author to whom correspondence should be addressed.
Received: 27 June 2014 / Revised: 22 July 2014 / Accepted: 1 September 2014 / Published: 10 September 2014
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Inappropriate antibiotic use leads to increased risk of antibiotic resistance and other adverse outcomes. The objectives of the study were to determine the prevalence and characteristics of antibiotic use in Egyptian hospitals to identify opportunities for quality improvement. A point prevalence survey was conducted in 18 hospitals in March 2011. A total of 3408 patients were included and 59% received at least one antibiotic, with the most significant use among persons <12 years and intensive care unit patients (p < 0.05). Third generation cephalosporin were the most commonly prescribed antibiotics (28.7% of prescriptions). Reasons for antibiotic use included treatment of community—(27%) and healthcare-associated infections (11%) and surgical (39%) and medical (23%) prophylaxis. Among surgical prophylaxis recipients, only 28% of evaluable cases received the first dose within two hours before incision and only 25% of cases received surgical prophylaxis for <24 h. The prevalence of antibiotic use in Egyptian hospitals was high with obvious targets for antimicrobial stewardship activities including provision of antibiotic prescription guidelines and optimization of surgical and medical prophylaxis practices. View Full-Text
Keywords: antibiotic use; prevalence survey; surgical prophylaxis; Egypt antibiotic use; prevalence survey; surgical prophylaxis; Egypt

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Talaat, M.; Saied, T.; Kandeel, A.; El-Ata, G.A.A.; El-Kholy, A.; Hafez, S.; Osman, A.; Razik, M.A.; Ismail, G.; El-Masry, S.; Galal, R.; Yehia, M.; Amer, A.; Calfee, D.P. A Point Prevalence Survey of Antibiotic Use in 18 Hospitals in Egypt. Antibiotics 2014, 3, 450-460.

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