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Biosensors 2018, 8(4), 92; https://doi.org/10.3390/bios8040092

Metal-Organic Frameworks for the Development of Biosensors: A Current Overview

Department of Organic Chemistry, Stockholm University, SE-106 91 Stockholm, Sweden
Received: 23 September 2018 / Revised: 8 October 2018 / Accepted: 13 October 2018 / Published: 16 October 2018
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Abstract

This review focuses on the fabrication of biosensors using metal-organic frameworks (MOFs) as recognition and/or transducer elements. A brief introduction discussing the importance of the development of new biosensor schemes is presented, describing these coordination polymers, their properties, applications, and the main advantages and drawbacks for the final goal. The increasing number of publications regarding the characteristics of these materials and the new micro- and nanofabrication techniques allowing the preparation of more accurate, robust, and sensitive biosensors are also discussed. This work aims to offer a new perspective from the point of view of materials science compared to other reviews focusing on the transduction mechanism or the nature of the analyte. A few examples are discussed depending on the starting materials, the integration of the MOF as a part of the biosensor and, in a deep detail, the fabrication procedure. View Full-Text
Keywords: metal-organic frameworks; polymer-based biosensors; MOF-based fluorescence biosensors; MOF-based electrochemical biosensors; MOF micro/nanostructuring metal-organic frameworks; polymer-based biosensors; MOF-based fluorescence biosensors; MOF-based electrochemical biosensors; MOF micro/nanostructuring
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Carrasco, S. Metal-Organic Frameworks for the Development of Biosensors: A Current Overview. Biosensors 2018, 8, 92.

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